Search Abstracts
Program

Session 54   Poster Session
Pathogenesis of Acute HIV Infection
4:30-6:30 pm
4E-F

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347-M.
Early Development of Neutralizing IgA Antibodies in Serum of Primary HIV-1-Infected Patients
J. Söderlund1, K. Broliden*1, V. Mallet2, H. Maseruka2, L. Goh2, and J. Andersson1
1Karolinska Inst., Stockholm, Sweden and 2GlaxoSmithKline, London, UK
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348-M. Impact of Primary CMV Infection or Reactivation on HIV and Immunological Parameters in Patients With Primary HIV Infection (PHI)
L. Goh*1, M. C. Bernard2, F. Lampe3, G. Janossy3, D. A. Cooper4, P. Cunningham4, J. Andersson5, A. Capt6, S. Kinloch3, H. McDade1, S. Turkish1, and L. Perrin2
1GlaxoSmithKline, Greenford, UK; 2Hosp. Cantonal, Geneva, Switzerland; 3Royal Free and Univ. Coll. Med. Sch., London, UK; 4NCHECR, Univ. of New South Wales, Sydney, Australia; 5Karolinska Inst., Huddinge, Sweden; and 6Roche Molecular Systems, Somerville, NJ
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349-M.
Analysis of HIV- and CMV-Specific Memory CD4 T-Cell Responses during Primary and Chronic Infections
A. Harari*1, K. Ellefsen1, G. P. Rizzardi1, D. Ciuffreda1, P. A. Bart1, P. Champagne1, S. Yerly2, L. Kaiser2, L. Perrin2, and G. Pantaleo1
1CHW, Lausanne and 2HCUGE, Geneva, Switzerland
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350-M.
Reduced CD4+ T-Cell Responses to Mitogen and Decreased Circulating CD123+ Dendritic Cells during Primary HIV-1 Infection
J. Zaunders*1, D. Smith2, P. Grey2, M. Bloch3, R. Finlayson4, L. Goh5, A. D. Kelleher2, and D. A. Cooper2
1St. Vincent’s Hosp., Darlinghurst, Australia; 2Natl. Ctr. in HIV Epidemiology and Clin. Res., Sydney, Australia; 3Univ. of New South Wales, Holdsworth House Gen. Practice, Sydney, Australia; 4Taylor Square Private Clin., Sydney, Australia; and 5GlaxoSmithKline, London, UK
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351-M. Activated CD8 Subsets and HIV-1 Viral Kinetics in Acute HIV-1 Infection
W. A. Blattner*1, K. A. Oursler1, F. Cleghorn1, M. Charurat1, A. Sill1 , C. Bartholomew2, N. Jack2, M. Greenberg3, G. Tomaras3, C. LaBranche3, and K. Weinhold3
1Inst. of Human Virology, Baltimore, MD; 2Med. Res. Fndn. of Trinidad and Tobago, Port of Spain; and 3Duke Univ., Durham, NC
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352-M. Preferential and Persistent Depletion of CCR5+ Th Lymphocytes with Non-Lymphoid Homing Potential in Primary HIV Infection
R. Krzysiek*1, A. Rudent 2, A. Lafeuillade4, D. Ingrand2 , D. Sereni3, P. Galanaud1, L. Grangeot-Keros2, and D. Emilie1 for the ANRS O86 PRIMOFERON A Study group
1INSERM U131 2Hosp. Antoine Béclère, Inst. Paris-Sud sur les Cytokines, Clamart; 3Hosp. Saint-Louis, Paris; 4Hosp. Chalucet, Toulon, France
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353-M.
HIV-1 Variants in Body Fluids during Primary HIV Infection: Findings from the Duke-UNC-Emory Acute HIV Consortium
D. C. Shugars*1, S. Freel1, K. Ritola1, C. Pilcher1, S. A. Fiscus1, J. Giner2, P. Menezes1, B. Dean3, E. Patrick3, K. Robertson3, C. E. Hart3, R. Swanstrom1, J. L. Lennox3, C. Hicks2, and J. J. Eron Jr.1
1Univ. of North Carolina, Chapel Hill; 2Duke Univ., Durham, NC; and 3Emory Univ., Atlanta, GA
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354-M. During Primary HIV Infection, HIV Replicates in HLA-DR- CD4+ T Lymphocytes as Actively as in HLA-DR + Fraction
N. Ngo-Giang-Huong*1, J. Van-Grevenynghe1, J. M. Doisne2, C. Deveau3 , M. Sinet2, A. Venet2, and C. Rouzioux1 for the PRIMO Cohort Study Group
1CHU Necker-Enfants Malades, Paris; 2INSERM EO 109, Paris; and 3INSERM U292, Kremlin-Bicetre, France
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355-M.
Distinct Patterns of HIV-1 Evolution in CD14+ Monocytes and CD4+ T Lymphocytes between Patients with and without HAART
J. Fulcher, Y. Hwangbo, J. Mullins, L. Corey, and T. Zhu*
Univ. of Washington Sch. of Med., Seattle
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356-M.
HIV-1 Evolutionary Dynamics in a Dually Infected HIV-1 Patient
F. Li*, R. Shankarappa, X. He, H. He, D. Nickle, M. Jensen, J. Mittler, J. B. Margolick, and J. Mullins
Univ. of Washington, Seattle
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357-M.
Genetic Variation in p6gag in Primary HIV Infection
D. Smith*1, S. J. Little1, E. S. Daar2, R. Koup3, N. S. Hellmann4, K. Dawson4, J. K. Wong1, D. D. Richman1, and A. J. Leigh Brown1
1Univ. of California, San Diego; 2Univ. of California, Los Angeles; 3Univ. of Texas Southwestern Med. Ctr., Dallas; 4ViroLogic, Inc., South San Francisco, CA; and 5Univ. of Edinburgh, UK
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358-M.

Quasi-Species Expansion without Adaptive Evolution in Seronegative S-HIV-Infected Macaques
S. Shapiro*1, M. Hsu1, J. Harouse1, C. Cheng- Mayer1, and P. Balfe2
1Aaron Diamond AIDS Res. Ctr., Rockefeller Univ., New York, NY and 2Windeyer Inst. for Molecular Med., Royal Free and Univ. Coll. Med. Sch., London, UK
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