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Program

Session 14   Oral Abstract Session
Molecular Virology
Tuesday, 10 am - 12:30 pm
6C

ModeratorsMichael Emerman, Fred Hutchinson Cancer Res. Ctr., Seattle, WA and Jaisri Lingappa, Univ. of Washington, Seattle

10:00 51. Recruitment of Tsg101 to Sites of Particle Assembly, Mediated by Short Peptide Motifs Is Required for Efficient HIV-1 and Ebola Virus Particle Budding
J. Martin-Serrano*, T. Zang, and P. D. Bieniasz
Aaron Diamond AIDS Res. Ctr., Rockefeller Univ., New York, NY
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10:15 52. Overexpressing the E2-Like Domain of Tsg 101 Supresses HIV-1 Budding by Blocking p6 Late Domain Activity
D. Demirov*, A. Ono, and E. Freed
NIH, Bethesda, MD
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10:30 53. Formation of an HIV-1 Core of Optimal Stability Is Crucial for Viral Replication
B. M. Forshey*1, U. von Schwedler2, W. I. Sundquist2, and C. Aiken1
1Vanderbilt Univ. Sch. of Med., Nashville, TN; and 2Univ. of Utah, Salt Lake City
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10:45 54. HIV-1 Vif Is Associated with HP68, a Host Protein that Appears to Be Essential for Immature Capsid Formation
K. Klein and J. Lingappa*
Univ. of Washington, Seattle
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11:00 55. The Identification of Cellular Host Factors Important for the HIV-1 Vif Phenotype
A. M. Sheehy*1 and M. H. Malim2
1Univ. of Pennsylvania, Philadelphia and 2King's Coll., London, UK
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11:15 56. A C-Terminal Nuclear Localization Signal in HIV-1 Integrase Mediates Viral Nuclear Import
D. R. Kaufman, B. Chai, J. Chang, N. Genoud, A. Steed, and M. Muesing*
Aaron Diamond AIDS Res. Ctr., Rockefeller Univ., New York, NY
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11:30 57. Interaction of HIV-1 Vpr with Cdc25C: Implications for G2 Arrest
W. C. Goh, N. Manel, and M. Emerman*
Fred Hutchinson Cancer Res. Ctr., Seattle, WA
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11:45 58. HIV Infection Results in G2 Cell Cycle Arrest In Vivo
M. P. Sherman*1, J. A. Neidleman1, S. Williams1, C. de Noronha1, D. Eckstein1, J. Kahn2, R. Hecht2, M. Warmerdam1, and W. C. Greene1
1Gladstone Inst. of Virology and Immunology; 2Positive Hlth. Prgm. at San Francisco Gen. Hosp., Univ. of California, San Francisco
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12:00 59. CD4-Bound Conformation of HIV-1 gp120 Improved by Introduced Disulfide Bonds
S.-H. Xiang*1, P. Kwong2, J. Vainshtein1, and J. Sodroski1
1Dana-Farber Cancer Inst., Boston, MA and 2NIAID Vaccine Res. Ctr., NIH, Bethesda, MD
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12:15 60. Effects of Compartmentalization on HIV-1 Nef Evolution
S. Pillai*1, J. Guatelli1,2, C. Spina1,2, S. Letendre1, R. J. Ellis1, J. K. Wong1,2, and D. D. Richman1
1Univ. of California, San Diego; and 2VA San Diego Healthcare System, CA
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