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Session 39
Poster Session
Envelope-Receptor Interactions 4:30-6:30 pm 4E-F |
to view the poster for an abstract.| 180-M. | Involvement of the Bridging Sheet of HIV-1 Envelope in Co-Receptor Interactions M. Biscone*, J. Reeves, F. Baribaud, S. Baik, and R. W. Doms Univ. of Pennsylvania, Philadelphia
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| 181-M. | Gp41-Mediated Apoptosis is Independent of HIV Co-Receptor Use but Requires Proper Presentation by gp120 J. Blanco*, J. Barretina, B. Clotet, and J. A. Esté Fndn. irsiCaixa, Barcelona, Spain
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| 182-M. | Early SIVsm Re-Isolates Show Broad Co-Receptor Use in Comparison with Late Re-Isolates Obtained from Experimentally Infected Cynomolgus Macaques D. Vödrös*1, 2, 3, R. Thorstensson4, G. Biberfeld4, D. Schols5, E. De Clercq5, E. M. Fenyö1, and 2 1Karolinska Inst., Stockholm, Sweden; 2Lund Univ., Sweden; 3 Natl. Ctr. for Epidemiology, Budapest, Hungary; 4Swedish Inst. for Infectious Disease Control, Stockholm, Sweden; and 5Rega Inst. for Med. Res., Leuven, Belgium
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| 183-M. | Contrasting Dependence on CCR5 Determinants by R5 and R5X4 Quasi-Species within 89.6 Primary Isolate A. Singh* and R. G. Collman Univ. of Pennsylvania, Philadelphia
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| 184-M. | Examination of HIV-1 Resistance to RANTES Derivatives through the Use of a Unique Recombinant Envelope Pseudo-Typing Method A. Marozsan*, A. Abraha, H. Baird, and E. Arts Case Western Reserve Univ., Cleveland, OH
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| 185-M. | The Cytoplasmic Domain of CCR5 Is Dispensable for Receptor Expression and for Function as HIV-1 Co-Receptor C. Pastore*1, G. Picchio1, F. Galimi2, O. Hartley 3, R. Offord3, and D. Mosier1 1Scripps Res. Inst., La Jolla, CA; 2Salk Inst., La Jolla, CA; and 3Ctr. Med. Univ., Geneva, Switzerland
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| 186-M. | HIV-1 Env Signaling in Primary Human Macrophages through CCR5 and CXCR4: Role in HIV-1 Pathogenesis M. Del Corno*, C. H. Lee, M. Chen, Q. H. Liu, B. Freedman, and R. G. Collman Univ. of Pennsylvania, Philadelphia
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| 187-M. | Mechanisms of HIV-1 Env-Activated Chemokine Receptor-Mediated Signal Transduction in Primary Human Macrophages C. H. Lee*, M. Del Corno, Q. H. Liu, B. Freedman, and R. G. Collman Univ. of Pennsylvania, Philadelphia
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| 188-M. | Induction of Syncitia and CD4-Independent Infection of B Cells by Primary HIV-1 Isolates B. Zerhouni*, J. Zhang, and K. Saha Children's Res. Inst., Ohio State Univ., Columbus
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| 189-M. | Structural and Functional Characterization of Human CXCR4 as a Chemokine Receptor and HIV-1 Co-Receptor by Mutagenesis and Molecular Modeling Studies N. Zhou*1, 2, Z. Luo1, J. Luo1, D. Liu1, 3, J. W. Hall1, R. J. Pomerantz2, Z. Huang1, and 3 1Kimmel Cancer Ctr., Philadelphia, PA; 2Jefferson Med. Coll., Thomas Jefferson Univ., Philadelphia, PA; and 3Univ. of Illinois, Urbana-Champaign
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| 190-M. | An Unusual Syncytia-Inducing HIV-1 Primary Isolate from the CNS that is Restricted to CXCR4, Replicates Efficiently in Macrophages, and Induces Neuronal Apoptosis Y. Yi*, I. Frank, J. Sulcove, D. L. Kolson, and R. G. Collman Univ. of Pennsylvania Sch. of Med., Philadelphia
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| 191-M. | Lipid Rafts and HIV Pathogenesis: Particle Cholesterol Is Required for Fusion and Entry into Host Cells Z. Liao and J. E. K. Hildreth* Johns Hopkins Sch. of Med., Baltimore, MD
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| 192-M. | R5-AIDS HIV-1 Clone Exhibits Higher CCR5 Binding Affinity than R5-Pre-AIDS Clones from the Same Patient A. Matthews*, R. Scoggins, K. Olivieri, J. Taylor Jr., D. Chernauskas, and D. Camerini Univ. of Virginia, Charlottesville
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| 193-M. | Pattern-Recognition Analysis of V3 Loop Sequences Suggests Single Amino Acid Changes Affect Co-Receptor Usage Only in a Complex Genetic Context F. Li*, D. Nickle, M. Jensen, A. van't Wout, H. He, and J. Mullins Univ. of Washington, Seattle
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| 194-M. | Changes in the V2 Region of gp120 during the Course of SHIVDH12R Infection Lead to CD4-Independent Virus Entry H. Imamichi*1, T. Imamichi1, H. C. Lane2, M. A. Martin2, and T. Igarashi2 1SAIC, Frederick, MD and 2NIAID, NIH, Bethesda, MD
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