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Program

Session 36   Poster Session
Vpr
4:30-6:30 pm
4E-F

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139-M.
Assessment of the Contributions of Vpr-Mediated G2/M Arrest and Nuclear Import to HIV-1 Replication in Culture
P. V. Sanchez*1 and M. H. Malim2
1Univ. of Pennsylvania, Philadelphia and 2King's Coll., London, UK
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140-M.
Cytoplasmic-Nuclear Shuffling of HIV-1 Vpr and Its Effect on Integrity of the Nuclear Envelope
R. T. Elder1, M. Yu1, J. Hou1, M. Chen1, S. Priet2, A. Sheerer1, K. Chiu1, J. Sire2, and Y. Zhao*1
1Northwestern Univ. Med. Sch., Chicago, IL and 2INSERM, Marseille, France
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141-M.
Involvement of HIV Vpr Protein in G2/M Arrest through Interaction with 14-3-3
M. Tsopanomichalou*1, T. Kino2, A. Gragerov1, G. Ilyina-Gragerova1, G. P. Chrousos2, and G. N. Pavlakis1
1NCI, NIH, Frederick, MD and 2NICHD, NIH, Bethesda, MD
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142-M.
Multicopy Suppressors and Enhancers of Cell Cycle G2 Arrest Induced by HIV-1 Viral Protein R (Vpr) in Fission Yeast (Schizosaccharomyces Pombe)
Z. Benko*, R. T. Elder, S. Innis, M. Yu, M. Chen, and Y. Zhao
Northwestern Univ. Med. Sch., Chicago, IL
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143-M.
Functional Significance of Naturally Occurring Mutants in HIV-1 Vpr
P. K. Tungaturthi*1, S. P. Singh1, M. Cartas1, B. Tomkowicz1, V. Ayyavoo2, S. Mahalingam3, R. Murali4, and A. Srinivasan1
1Thomas Jefferson Univ., Philadelphia, PA; 2Univ. of Pittsburgh, PA; 3Ctr. for DNA Fingerprinting and Diagnostics, Hyderabad, India; and 4Univ. of Pennsylvania, Philadelphia
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144-M. Physical and Functional Interaction between Viral Protein R and p21WAFI
B. E. Sawaya1, S. P. Singh*2, K. Khalili1, A. Clavo1, A. Srinivasan2, and S. Amini1
1Temple Univ. and 2Thomas Jefferson Univ., Philadelphia, PA
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145-M.
HIV-1 Vpr Causes Cell Cycle Arrest via a Pathway Involving p38 MAP Kinase and ATR
M. Roshal*, Y. Zhu, and V. Planelles
Univ. of Rochester, NY
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146-M.
Vpr Mutation R77Q Is Associated with Long-Term Non-Progressive HIV-Infection and an Impaired Ability to Induce T-Cell Depletion in Vivo
J. Lum*1, O. J. Cohen2, D. H. Lynch4, A. A. Pilon1, J. E. Kim2, Z. Chen3, M. Montpetit3, J. Sanchez-Dardon1, N. Hawley-Foss1, G. Garber1, and A. D. Badley1
1Ottawa Hlth. Res. Inst., Ontario, Canada; 2NIAID, NIH, Bethesda, MD; 3Hlth. Ottawa, ON, Canada; and 4Immunex Corp., Seattle, WA
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