Search Abstracts
Program

Session 41   Poster Session
CD4 T-Helper Responses to HIV
4:30-6:30 pm
4E-F

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203-T. T Helper Cell Induction in Patients with Primary HIV-1 Infection and Long-Term Non-Progressive Disease
U. Malhotra*1,2, S. Holte1, S. Emery1, J. Lee1, J. Marenza1,2, L. Corey1,2, and M. J. McElrath1
1Fred Hutchinson Cancer Res. Ctr.and 2Univ. of Washington, Seattle
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204-T. Induction and Persistence of Envelope-Specific T Helper Cells Following Acute HIV-1 Infection
U. Malhotra*1,2, T. Zhu2, E. Delpit2, C. Huntsberry1, A. Sette3, R. Shankarappa4, and M. J. McElrath1
1Fred Hutchinson Cancer Res. Ctr., Seattle, WA; 2Univ. of Washington, Seattle; 3Epimmune, San Diego, CA; and 4Allegheny-Singer Res. Inst., Pittsburgh, PA
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205-T.
Optimum Peptide Length for Stimulating HIV-1-Specific T-Helper Cell Clones
P. Norris*, H. Moffett, L. Cosimi, B. Walker, and E. Rosenberg
Massachusetts Gen. Hosp. and Partners AIDS Res. Ctr., Boston
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206-T.
CD4+ T-Cell-Mediated Cytolytic Activity in HIV-1 Infection
P. Norris*1, M. Sumaroka2, H. Moffett1, Y. Sykulev2, B. Walker1, and E. Rosenberg1
1Massachusetts Gen. Hosp. and Partners AIDS Res. Ctr., Boston, and 2Thomas Jefferson Univ., Philadelphia, PA
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207-T.
HIV-1-Specific T-Helper Cell Responses in Long-Term Non-Progressors and Acute Seroconverters
L. Cosimi*, H. Truong, B. Wilkes, D. Strick, B. Walker,, and E. Rosenberg
Partners AIDS Res. Ctr. and Massachusetts Gen. Hosp., Boston
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208-T.
HIV-1 Replication in Vivo Is Associated with Suppression of HIV-1-Specific CD4+ T-Cell Proliferation but not with Loss of HIV-1-Specific IFN-gamma Producing CD4+ T Cells
B. Palmer*, E. Boritz, and C. C. Wilson
Univ. of Colorado Hlth. Sci. Ctr., Denver
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209-T.
Repertoire Diversity of HIV-1 p24-specific CD4+ T Cell Clones
E. Boritz*1, B. Palmer1, B. Livingston2, and C. C. Wilson1
1Univ. of Colorado Hlth. Sci. Ctr., Denver; and 2Epimmune, San Diego, CA
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210-T.
Large Oligoclonal CD4+ T-Cell Expansions in HIV-1-Infected Patients Persist with an Altered Surface Phenotype after 3 Years of Viral Suppression
S. Bennett*, L. Goodwin, B. Kotzin, E. Connick, and the ACTG 315/375 Team
Univ. of Colorado Hlth. Sci. Ctr., Denver
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211-T. Substantial Rate of Lymphoproliferative Response to HIV-1-Specific Antigens after Prolonged Suppression of Viral Replication with HAART
G. Breton*1, D. S. Algara2, X. Duval1, P. Longuet1, J. L. Ecobichon1, C. Leport1, and J. L. Vildé1
1Bichat Hosp.; and 2Pasteur Inst., Paris, France
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212-T.
Correlation between Frequencies of HIV-1-p24-Specific Th1 Cells (ELISPOT) and Plasma HIV-1 Viral Load in a Cohort of LT-NP and Slow Progressors
V. Martinez*1, N. Alatrakchi1, D. Costagliola2, O. Bonduelle1, H. Agut1, and B. Autran1 for the ALT Study Group
1Hosp. Pitié-Salpêtrière and 2Faculté de Méd. Saint-Antoine, Paris, France
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213-T.
Skewed Differentiation of HIV-Specific CD4 Memory Effector T Cells
A. Harari*, S. Petitpierre, G. P. Rizzardi, and G. Pantaleo
CHUV, Lausanne, Switzerland
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214-T.
Defects in CD4+ T-Cell-Mediated B Cell Help in HIV-Infected Patients
S. Moir*, K. Ogwaro, A. Malaspina, L. Ehler, S. Liu, M. McLaughlin, M. Dybul, T. W. Chun, and A. S. Fauci
NIAID, NIH, Bethesda, MD
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215-T.
Anergy State of HIV-Specific CD4+ T Cells Detected by Class II Tetramers but Suppressed by Several Stimuli
B. Yassine Diab*1, G. Breton1, S. Younes1, M. Connors2, M. Lainesse1, N. F. Bernard3, K. MacDonald4, M. Legault4, J. P. Routy4, and R. P. Sekaly1
1Univ. of Montreal, QC, Canada; 2NIAID, NIH, Bethesda, MD; 3McGill Univ. Med. Ctr., Montreal, QC, Canada; and 4Univ. of Toronto, ON, Canada
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216-T.
Complete Supression of Proliferation Despite Persistence of Virus Specific CD4+ T Cells during HIV Viremia
C. A. Iyasere*, J. C. Tilton, S. Migueles, A. Laborico, and M. Connors
NIAID, NIH, Bethesda, MD
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