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Program

Session 40   Poster Session
Chemokines and Chemokine Receptors
4:30-6:30 pm
4E-F

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195-M. Direct Receptor Cross-Talk between CD4 and CCR5
R. Staudinger*1, S. Phogat2, X. Wang1, D. S. Dimitrov2, and S. Zolla-Pazner1
1New York Univ. Sch. of Med. and VA Med. Ctr., New York and 2NCI, NIH, Frederick, MD
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196-M.
Amino Acid Residues Critical for LD78beta (a Major Variant of Human MIP-1alpha) Binding to CCR5 and Inhibition of R5 HIV-1 Replication
T. Miyakawa*1 , K. Obaru1, K. Maeda1, S. Harada1, H. Mitsuya1, and 2
1Kumamoto Univ. Sch. of Med., Kumamoto, Japan and 2NCI, NIH, Bethesda, MD
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197-M.
Implication of beta-Chemokines MIP-1alpha, RANTES and MIP-1beta on the Protection From the HIV-1 Infection and Disease Progression
C. Martínez*1, M. Plana1, A. Soriano1, F. García1, M. J. Maleno1, A. García1, J. Aróstegui1, J. Miró1, J. Del Romero2, C. Rodriguez1, J. I. Lorenzo3, J. M. Gatell1, and T. Gallart1
1Univ. of Barcelona; 2Ctr. Médico Sandoval, Madrid; and 3Hosp. La Fe, Valencia, Spain
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198-M.
Expression of CCR5 on Dendritic Cells Is a Surrogate Marker for HIV Disease Progression
B.-J. Zheng1, S.-K. Leung1, K.-H. Wong2, and S.-S. Lee2
1The Univ. of Hong Kong and 2Integrated Treatment Ctr., Hong Kong
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199-M.
Plasma SDF-1 Levels, SDF1-3A Genotype and CXCR4 Expression on T Lymphocytes and Their Impact on Resistance to HIV-1 Infection and Its Progression
A. Soriano1, C. Martinez1, F. García1, M. Plana1, E. Palou1, J. Aróstegui, M. Leujeune1, J. Joseph1, J. Miró1, J. del Romero2, C. Rodriguez2, A. Barrasa2, J. I. Lorenzo3, J. M. Gatell*1, and T. Gallart1
1Univ. of Barcelona; 2Ctr. Med. Sandoval, Madrid; and 3Hosp. La Fe, Valencia, Spain
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200-M.
SDF-1alpha Protection of HIV-1 Envelope Glycoprotein-Induced Apoptosis in Human B Lymphocytes via Mitochondrial Integrity
C. Patke* and W. Shearer
Texas Children's Hosp. and Baylor Coll. of Med., Houston
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201-M.
Leukocyte Elastase Cleaves Stromal Cell-Derived Factor-1 (SDF-1) and CXCR4 HIV-1 Co-Receptor: Control of the Anti-VIH Activity of SDF-1
A. Valenzuela-Fernández*1, T. Planchenault1, I. Staropoli1, F. Baleux1, D. Leduc1, K. Le Barillec1, M. Chignard1, T. Delaunay2, J-L. Virelizier1, D. Pidard1, and F. Arenzana-Seisdedos1
1Pasteur Inst., Paris; and 2INRA, Villeneuve d’Ornon, France
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202-M.
CXCR4-Triggered CD4 and CD8 T-Cell Apoptosis by HIV env Is Mediated by p38 MAP Kinase
A. Villasis-Keever*, G. Bou, M. Vanegas, T. Gomez, S. Vlahakis, and C. V. Paya
Mayo Clin., Rochester, MN
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