Search Abstracts
Program

Session 97   Poster Session
Neuropathogenesis
4:30-6:30 pm
4E-F

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731-W.
HIV-1 Replication Block in Microglial Infection as a Potential Model for Latency
R. Vos*, A. Albright, and F. González-Scarano
Univ. of Pennsylvania, Philadelphia
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732-W.
Primary Isolated Human Brain Microvascular Endothelial Cells (MVECs) Express Diverse HIV/SIV-Associated Chemokine Co-Receptors and DC-SIGN/L-SIGN
M. Mukhtar*1, S. Harley1, P. Chen2, M. BouHamdan1, C. Patel1, E. Acheampong1, and R. J. Pomerantz1
1Thomas Jefferson Univ., Philadelphia, PA and 2Univ. of Pennsylvania, Philadelphia
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733-W. Changes in Cell Adhesion Molecule and Chemokine Receptor Expression on HIV-Specific CTL Migrating to Cerebrospinal Fluid
R. W. Price*1, C. A. Cox2, D. T. Wilkens2, J. Neuenburg2, A. Nilsson1, D. F. Nixon2, and B. L. Shacklett2
1San Francisco Gen. Hosp. and 2Gladstone Inst. of Virology and Immunology, Univ. of California, San Francisco, CA
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734-W.
Intracellular HIV-1 p24 Expression in Cerebrospinal Fluid T Cells by Flow Cytometry
J. Neuenburg*1,2, M. Warmerdam1, A. Nilsson2, R. W. Price2, and R. M. Grant1
1Gladstone Inst. of Virology and Immunology, San Francisco, CA and 2Univ. of California, San Francisco
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735-W. Molecular Basis for Neurovirulence of CCR5 Tropic HIV-1 Isolates from Brain
P. Gorry*1, J. Taylor2, G. Holm1, A. Mehle1, J. Moore3, T. Morgan3, M. Cayabyab1, M. Farzan1, J. Bell4, S. Wolinsky2, and D. Gabuzda1
1Dana-Farber Cancer Inst., Boston, MA; 2Northwestern Univ., Chicago, IL; 3Weill Med. Coll. of Cornell Univ., New York, NY; and 4Univ. of Edinburgh, UK
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736-W.
Chemokine Regulation by HIV-1 and Pro-Inflammatory Cytokines in Human Astrocytes and Neurons
D. M. Lawrence*, L. C. Durham, T. W. Sanchez, and E. O. Major
NINDS, NIH, Bethesda, MD
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737-W.
HIV-1 gp120-Mediated Neuronal Death: The Direct and Indirect Neurotoxic Effects of Viral Sequence Diversity
K. Zhang* and C. Power
Univ. of Calgary, AB, Canada
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738-W. IL-1 beta-Activated Astrocytes Express Fas Ligand: Novel Pathways to Neuronal Injury in HIV-1-Associated Dementia
A. Ghorpade*, K. Borgmann, C. Schellpepper, S. Holter, R. Persidsky, J. Zheng, H. E. Gendelman, L. Wu, and R. Suryadevara
Univ. of Nebraska Med. Ctr., Omaha
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739-W.
Potential Links between Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) and Macrophage-Mediated Neuronal Injury in the Pathogenesis of HIV-1-Associated Dementia
L. A. Ryan*, A. L. Lopez, A. Ghorpade, H. E. Gendelman, and J. Zheng
Univ. of Nebraska Med. Ctr., Omaha
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740-W.
Apoptosis of Astroglial Cells Is Related to Oxidative Stress Induced by HIV-1-Infected Macrophages, and Counteracted by a SOD Mimetic Compound with a Potent Anti-HIV-1 Activity
S. Aquaro*1, D. Salvemini2, D. P. Riley2, C. Muscoli3, T. Granato4, A. Modesti1, D. Rotiroti3, R. Nisticň1, V. Mollace3, and C. F. Perno1
1Univ. of Rome "Tor Vergata", Italy; 2MetaPhore Pharmaceuticals, St. Louis, MO; 3Univ. of Catanzaro "Magna Graecia", Italy; 4IBAF Ctr. CNR, Catanzaro, Italy; and 5IRCCS "L. Spallanzani", Rome, Italy
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741-W.
Intracellularly Expressed HIV TAT in Astrocytes Promotes Astrocyte Survival but Induces Neurotoxicity
A. Chauhan*, S. Roth , J. Turchan , R. Reid, and A. Nath
Univ. of Kentucky, Lexington
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742-W. OTK18: A Transcriptional Suppressor Induced by HIV-1 Infection of Mononuclear Phagocytes and Its Relevance to HIV-1 Dementia
J. Limoges*1, K. A. Carlson1, G. Leisman1, E. Masliah2, H. E. Gendelman1, and T. Ikezu1
1Univ. of Nebraska Med. Ctr., Omaha and 2Univ. of California, San Diego
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743-W.
The Regulation of Neurotrophic Factor Activities Following HIV-1 Infection and Immune Activation of Mononuclear Phagocytes
A. L. Lopez, R. L. Cotter, D. A. Erichsen, H. Peng, L. Gendelman, A. Shibata, H. E. Gendelman, and J. Zheng*
Univ. of Nebraska Med. Ctr., Omaha
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