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Session 25
Oral Abstract Presentations Viral Pathogenesis Thursday 10 am - 12:30 pm Ballroom A |
| Moderators: | Amitinder Kaur New England Regional Primate Res Ctr, Harvard Med Sch, Southborough, MA and Richard Koup NIAID Vaccine Res Ctr, NIH, Bethesda, MD |
| 10:00 120 | Limited Role of Cellular Immune Responses in SIV-infected Sooty Mangabeys A P Barry*, B Sumpter, G Silvestri, S I Staprans, M B Feinberg Emory Univ, Atlanta, GA |
| 10:15 121 | Increased SIV Viremia Following In Vivo CD8+ T-lymphocyte Depletion in Sooty Mangabeys with Natural SIV Infection Z. Wang1, N. Kassis1, S. Staprans2, M. Elliott1, S. O’Neil1, J E Schmitz3, K. A. Reimann3, H. M. McClure2, R. P. Johnson1, A. Kaur*1 1New England Regional Primate Res Ctr, Southborough, MA; 2Yerkes Natl Primate Res Ctr, Emory Univ, Atlanta, GA; and 3Beth Israel Deaconess Med Ctr, Boston, MA |
| 10:30 122 | T-cell Subsets that Harbor HIV In Vivo: Implications in HIV Pathogenesis J. Brenchley*, D. Ambrozak, B. Hill, M. Betts, M. Roederer, D. Douek, R. Koup Natl Inst of Hlth, Bethesda, MD |
| 10:45 123 | Systematic Analysis of Host Factors Modifying CD4+ Cell Permissiveness to HIV-1 A. Ciuffi*, G. Bleiber, R. Martinez, C. Suarez, A. Telenti CHUV Lausanne, Switzerland |
| 11:00 124 | Viral Kinetics of SIV mac251 in Acute Infection: Estimation of the "Basic Reproductive Ratio" Hiroshi Mohri*1, Naureen Mushtaq1, Rudolph Bohm2, Agegnehu Gettie2, Ruy Ribeiro3, Alan S. Perelson3, David D. Ho1 1Aaron Diamond AIDS Res Ctr, New York, NY; 2Tulane Reg Primate Res Ctr, Convington, LA; and 3Los Alamos Natl Lab, NM |
| 11:30 126 | Dual HIV-1 Infection Associated with Rapid Disease Progression Geoffrey S. Gottlieb*1, David C. Nickle1, Mark A. Jensen1, Kim G. Wong1, Fusheng Li1, Shan-Lu Liu1, Cecilia Rademeyer2, Gerald H. Learn1, Salim S. Abdool Karim3, Carolyn Williamson2, Lawrence Corey1, Joseph B. Margolick4, James I. Mullins1 1Univ of Washington,Seattle; 2Univ of Cape Town, South Africa; 3Univ of Natal, Durban, South Africa; and 4Johns Hopkins Bloomberg Sch of Publ Hlth, Baltimore, MD |
| 11:45 127 | Selective Heterosexual Transmission of Envelope-constrained, Neutralization-sensitive HIV-1 C.A. Derdeyn*1, J.M. Decker1,2, F. Bibollet-Ruche1, M.L. Heil1, S.A. Trask3, D.T. Chen1, F. Kasolo4, R. Musonda5, B.H. Hahn1, G.M. Shaw1,2, S. Allen1, E. Hunter1 1Univ of Alabama at Birmingham; 2Howard Hughes Med Inst, Birmingham, AL; 3Affymetrix, Santa Clara, CA; 4Univ Teaching Hosp, Lusaka, Zambia; and 5Tropical Disease Res Ctr, Ndola, Zambia |
| 12:00 128 | HIV-infected Patients Have a Defect in B-cell-CD4+ T-cell Interactions That Is Dependent on the Presence of Viremia A. Malaspina*, S. Moir, L. Ehler, S. Liu, M. Mclaughlin, A. Marie Planta, M. Dybul, T-W. Chun, A. Fauci Natl Inst of Allergy and Infectious Diseases, NIH, Bethesda, MD |
| 12:15 129 | Pharmacological Cellular Sanctuaries in T- and NK-cells Resistant to Protease Inhibitors A. Valentin*, R.H. Poirier, M. Morrow, K. Aleman, R. Yarchoan, R. Little, G.N. Pavlakis Natl Cancer Inst, Frederick, MD |
| 11:15 125lb | Mechansim of CCR5 viral dominace in macaques coinfected with CXCR4- and CCR5- SHIV J.M. Harouse*1, C. Buckner1, A. Gettie1, R. Fuller1, R. Bohm2, J. Blanchard2, C. Cheng-Mayer1 1Aaron Diamond AIDS Reseacrh Center, The Rockefeller University, New York, New York and 2Tulane National Primate Research Center, Tulane University Medical Center, Covington, LA |