Search Abstracts Program


Session 36   Poster Presentations
Accessory Genes
Tuesday 1:30 - 3:30 pm
Hall D
200HIV-1 Vif can Substitute Functionally for SIV Vif Replication in Human But Not in Rhesus Monkey Cells
S. Kar*, L. Alexander
Yale Univ, New Haven, CT
201An Alteration in HIV-1 Gag Relieves the Block at Reverse Transcription in Primate Cells
C. Muenk*, N. A. Kootstra, G. Lucero, S. M. Brandt, I. M. Verma, N.R. Landau
Salk Inst for Biological Studies, La Jolla, CA
202Enzymatic Activity of CEM15 is Essential for its Function to Suppress the Infectivity of deltaVif Virion
A. Takaori-Kondo*, K. Shindo, M. kobayashi, A. Arukin, T. Uchiyama
Grad Sch of Med, Kyoto Univ, Kyoto, Japan
203Enhanced CD4 Down-modulation Allows Efficient Replication of Late-stage HIV Strains
J Lama*, E Argañaraz
Univ of California at San Diego, La Jolla
204Co-receptor Dependent Stimulation of HIV-1 Replication in Primary T-cells by Nef
Christopher A. Lundquist*, Jing Zhou, Derya Unutmaz, Christopher Aiken
Vanderbilt Univ Sch of Med, Nashville, TN
205Disassembly of HIV-1 Cores In Vitro Reveals an Association of Nef with the Subviral Ribonucleoprotein Complex
Brett M. Forshey*, Christopher Aiken
Vanderbilt Univ, Nashville, TN
206The Association of HIV-1 Nef with Lipid Rafts is Functionally Important for CD4 and MHC Class I Down-modulation
Melissa Alexander Heaton*, Kodi S Ravichandran, Marie-Louise Hammarskjold, David Rekosh
Univ of Virginia, Charlottesville
207Vascular Endothelial Cells Induce Dramatically Higher Levels of HIV-1 Replication in a Nef-dependent Manner
J. Choi, J. Walker, J.S. Pober, L. Alexander*
Yale Univ, New Haven, CT
208Nef Expressed from Integrase Defective HIV-1 Down-regulates CD4 Expression
L. Gillim*, M. Klotman
Mt Sinai Sch of Med, New York, NY
209Evidence of a Novel Nef Activity Involved in nef-Mediated Thymocyte Depletion in the Thymus
R. D'Agostin*, L. Su
Univ of North Carolina, Chapel Hill
210HIV-1 Nef Impairs Generation of Thymic CD4+ T-cells
P. Chrobak*, M.C. Simard, T.M. Ndolo, Z. Hanna, P. Jolicoeur
Clin Res Inst of Montréal, Canada
211Characterization of CD4+ and CD8+ T-lymphocytes in CD4C/HIV nef Transgenic Mice: Their Presence is Dispensable for the Development of a Severe AIDS-like Disease
P. Chrobak*1, X. Weng1, E. Priceputu1, J. Poudrier1, D.G. Kay1, Z. Hanna1, T.W. Mak2, P. Jolicoeur1
1Clin Res Inst of Montréal, Canada and 2Ontario Cancer Inst, Univ of Toronto, Canada
212Identification of the Domain within the Subtype C Vpu that is Responsible for Efficient Transport to the Cell Surface
D K Singh, E Pacyniak, D Hout, E B Stephens*
Univ of Kansas Med Ctr, Kansas City
213Activation of the ATR-initiated DNA Damage Signaling Pathway by HIV-1 Vpr
V. Planelles1, S. Murala1, J. Walker1, M. Roshal*2
1Univ of Utah Sch of Med, Salt Lake City and 2Univ of Rochester, NY
214Glucocorticoid Receptor Modulates HIV-1 Replication Through Interaction with the Leucine Motifs in Helix I and III of Vpr
D Kumar*1, S Mahalingam2, M Wagner1, B Gray1, SP Singh3, A Srinivasan3, P Gupta1, V Ayyavoo1
1Univ of Pittsburgh, PA; 2Ctr For DNA Fingerprinting and Diagnostics, Hyderabad, India; and 3Thomas Jefferson Univ, Philadelphia, PA
215HIV-1 Vpr Alters the Phophorylation of hVIP/mov34
Michelle L Janket*1, Sundrasamy Mahalingam2, Velpandi Ayyavoo1
1Univ of Pittsburgh, PA and 2Ctr for DNA Fingerprinting and Diagnostics, Hyderabad, India
216Structure of Purified Intracellular HIV-1 Reverse Transcription Complexes
Ariberto Fassati*1, Milan V. Nermut2
1Univ Coll of London, UK and 2Natl Inst of Biological Standards and Controls, Potters Bar, UK
217Molecular Basis of Human Immunodeficiency Virus Type 1 Vpr-associated Cytopathicity in Human CD4+ T-cells
D. L. Bolton*1,2, M. J. Lenardo1
1Natl Inst of Allergy and Infectious Diseases, NIH, Bethesda, MD and 2Johns Hopkins Univ, Baltimore, MD
218Molecular Analysis of HIV-1 Induced CD4+ T-lymphocyte Cytopathicity
K. Sakai*1, J. Dimas1,2, M. J. Lenardo1
1Natl Inst of Allergy and Infectious Diseases, NIH, Bethesda, MD and 2Univ of Texas Hlth Sci Ctr, San Antonio
219Small Heat Shock Proteins Antagonize HIV-1 Vpr Activities through a MAPK-independent Mechanism
Zigmond Benko*1, Jason Hou1, Dong Liang1, Karen Chiu1, Paul G. Young2, Lorena Taricani2, Min Yu1, Scott Innis1, Patrick Reed1, Paola DiMarzio3, Michael Bukrinsky3, Yuqi Zhao1
1Northwestern Univ, Chicago, IL; 2Queen's Univ, Kingston, Canada; and 3George Washington Univ, Washington, DC