Search Abstracts Program


Session 43   Poster Presentations
Mapping CTL Epitopes in Different Populations
Wednesday 1:30 - 3:30 pm
Hall D
321HIV-1 Regulatory Protein (nef, tat, rev, vif, vpu, vpr)-CTL Responses and Epitope Mapping in Subtype A/E-Infected Thais with CD4 >300 cells/mm3
S. Buranapraditkun*1, K. Ruxrungtham1, S. Sirivichayakul1, S. Kosonsiriluk1, S. Kerdsanti1, P. Hansasuta1, S. Rowland-Jones2, P. Phanuphak1
1Bangkok, Thailand and 2Oxford, UK
322A Novel HLA-Cw1-restricted gag A/E CTL Epitope, YSPVSILDI, Identified in HIV-1 Infected Thai Patients
K Ruxrungtham*1, S Buranapraditkun1, P Hansasuta1, S Rowland-Jones2, S Sirivichayakul1, M Honda3, P Warachit1, P Phanuphak1
1Bangkok, Thailand; 2Oxford, UK; and 3Tokyo, Japan
323Differences in the Expressed HLA Class I Alleles Determine the Differential Clustering of HIV-1-Specific T-cell Responses in Infected Chinese and Caucasians
X. G. Yu*1, B. Perkins1, M. M. Addo1, F. Wei2, A. Rathod1, M. Parta3, P. Lee1, C. Adams1, A. Wurcel1, N. Frahm1, E. S. Rosenberg1, C. Brander1, Y. Cao2, B. D. Walker1, M. Altfeld1
1Partners AIDS Res Ctr, Mass Gen Hosp /Div of AIDS, Harvard Med Sch, Boston, MA; 2Chinese Academy of Preventive Med, Beijing, China; and 3Belvue Hosp, New York, NY
324Cross-reactive HIV-1 Clade B CD8+ T-lymphocytes in Patients Infected with HIV-1 Subtype A/G (CRF02) Living in Ivory Coast (West Africa)
A. Inwoley*1, P. Recordon2, A. Minga3, J. Gaston4, M. Dupuis4, B. Masquelier2, H. Fleury2, F. Rouet1, J. G. Guillet4, M. Andrieu4, ANRS 1220 PRIMOCI group3
1CeDReS/PAC-CI, Abidjan, Côte d'Ivoire; 2Lab de Virologie, Univ de Bordeaux, France; 3PRIMO-CI/PAC-CI, Abidjan, Côte d'Ivoire; and 4Inst Cochin, Paris, France
325Nef-specific CD8+ T-cells in HIV-1 Subtype C Infected Individuals Target a Highly Conserved Epitope-rich Central Region Restricted by Novel and Unpredicted HLA Class I Alleles Common in Southern Africa
T. Mashishi*1, S. Nyoka1, P. Mohube1, G. Khoury1, M. Paximadis1, A. Puren1, R. Donovan2, C. Williamson3, H. Sheppard2, C. Gray1
1Natl Inst for Communicable Diseases, Johannesburg, South Africa; 2HIV Vaccine Trials Network Central Lab, Richmond, CA; and 3Univ of Cape Town, South Africa
326Tools for Searching Optimal CTL Epitopes in Reactive Regions
K. Yusim*1, C. Calef1, K. Kommander1, J. J. Szinger1, B. T. Korber1,2
1Los Alamos Natl Lab, NM and 2Santa Fe Inst, NM
327HIV Adaptation to HLA-restricted Immune Responses-Implications for Vaccine Design and Evaluation
S. A. Mallal*, C. B. Moore, F. Carvalho, A. Patterson, C. Liu, D. Goodridge, D. Sayer, I. James, M. John
Ctr Clin Immunology and BioMed Statistics, Perth, Australia
328Sequence Analysis and Identification of CTL Escape
Yi Liu*1, David C. Nickle1, Jianhong Cao2, Hong Zhao1, Indira Genowati1, John McNevin2, Katie Davis1, Lisa Rose1, M. Juliana McElrath2, James I. Mullins11
1Univ of Washington, Seattle and 2Fred Hutchinson Cancer Res Ctr, Seattle, WA
329Frequency of CD8 T-cell Responses to Novel HIV-1 Specific Epitopes Among Individuals of Different Racial Backgrounds
S. Sabbaj1, A. Bansal1, D. Ritter1, C. Perkins1, B. Edwards1, E. Gough1, J. Tang1, B. Korber2, C. Wilson1, R. Kaslow1, M. Mulligan1, P. Goepfert1
1Univ of Alabama at Birmingham and 2Los Alamos Natl Lab, NM