Search Abstracts Program


Session 46   Poster Presentations
DC-SIGN and Related Molecules
Thursday 1:30 - 3:30 pm
Hall D
356The Interaction of DC-SIGN with HIV-1 gp120
A. Lekkerkerker*, S. van Vliet, Y. van Kooyk, T. Geijtenbeek
Free Univ Med Ctr, Amsterdam, The Netherlands
357Transmission of Cell-surface Bound Human Immunodeficiency Virus Type 1: Interaction Between Cell-surface LFA-1 and Virus-bound ICAM-1 Take Over Interactions Between Cell-surface DC-SIGN and Virus-anchored gp120/ICAM-3
S Bounou*, J F Giguère, R Cantin, M J Tremblay
Infectious Diseases Res Ctr, CHUL, Faculty of Med, Laval Univ, Québec, Canada
358DC-SIGN Interactions with Feline Immunodeficiency Virus
Aymeric de Parseval 1, Stephen V. Su2, John Elder 1, Benhur Lee *2
1Scripps Res Inst, La Jolla, CA and 2Geffen Sch of Med at UCLA, Los Angeles, CA
359HIV Envelope (gp120) Binding to DC-SIGN and Primary Dendritic Cells is Carbohydrate Dependent but Does Not Involve 2G12 or Cyanovirin Binding Sites: Implications for Structural Analyses of gp120 DC-SIGN Binding
Patrick Won-Pyo Hong*1, Karen Flummerfelt1, Aymeric de Parseval2, Kevin Gurney1, John Elder2, Benhur Lee1
1Univ of California at Los Angeles and 2Scripps Res Inst, La Jolla, CA
360DC-SIGN Mediated Transmission of HIV-1 is Cell Type Restricted
Li Wu*, Thomas D. Martin, Yoon-Chi Han, Sabine K.J. Breun, Vineet N. KewalRamani
NCI-Frederick, MD
361Structure-function Studies of DC-SIGN Interactions with gp120, ICAM-2, and ICAM-3
Stephen V. Su*, Patrick Hong, Karen Flummerfelt, Oscar Negrete, Benhur Lee
Geffen Sch of Med at UCLA, Los Angeles, CA
362Mechanisms of HIV-1 Attachment to Immature Dendritic Cells
R. Gummuluru*1,2, M. E. Rogel1, M. Emerman1
1Fred Hutchinson Cancer Res Ctr, Seattle, WA and 2Boston Univ Sch of Med, MA
363Role of pH in the DC-SIGN/HIV Interaction
C. Davis*, S. Pöhlmann, G. Leslie, F. Baribaud, R. Doms
Univ of Pennsylvania Sch of Med, Philadelphia
364HIV-1 and Other Pathogens Target DC-SIGN to Affect Immune Responses
T. Geijtenbeek*, S. van Vliet, E. Koppel, M. Sanchez-Hernandez, B. Appelmelk, Y. van Kooyk
VU Med Ctr, Amsterdam, The Netherlands
365Variations of Dendritic Cells Subsets, NK Cells Proportions and Functions in the First Days of Rectal SIV Infection
K. Petitprez*1, S. Kahi1, A. Couedel-Courteille2, P. Lebon3, A. Hosmalin1, C. Butor1,2
1Cochin Inst, Paris, France; 2Paris 7 Univ, France; and 3St Vincent de Paul Hosp, Paris, France
366Development of Soluble DC-SIGN and Characterization of HIV Binding Activity
H. Jia*, J. Li, S. T. Butera
HIV and Retrovirology Branch, CDC, Atlanta, GA
367DC-SIGNR Oligomers Binding to gp120, Deglycosylated gp120 and ICAM-3
G. A. Snyder*1, M. Colonna2, P. D. Sun1
1Natl Inst of Allergy and Infectious Diseases, NIH, Rockville, MD and 2Washington Univ Sch of Med, St Louis, MO
368Characterization of DC-SIGNR Transcript Isoforms from Human Dendritic Cells and Rectum Biopsies
H. Liu*1, F. Hladik2, P. J. Nelson2, J. Lee2, L. Corey1,2, M. J. McElrath1,2, T. Zhu1
1Univ of Washington, Seattle and 2Fred Hutchinson Cancer Res Ctr, Seattle, WA
369Cytokine Regulation of DC-SIGN Expression in Human Monocytes and Effect on HIV-1 Transmission
J. Chehimi, L. Azzoni*, Q. Luo, L. Shawver, N. Ngoubilly, R. June, G. Jerandi, E. Papasavvas, L. Montaner
Wistar Inst, Philadelphia, PA
370Attempt to Localize the Binding of DC-SIGN on gp120
J. Ford*, D. Atibalentja, J. Arthos, P. Sun
Natl Inst of Allergy and Infectious Diseases, NIH, Rockville, MD
371Mutational Analysis of the DC-SIGN Cytoplasmic Tail in the Mechanism of HIV-1 Transmission
S. Breun*, J. Baumann, T. Martin, V. KewalRamani
NCI-Frederick, MD
372Study of the Role of Mannose Binding Lectine and DC-SIGN in Discordant Partners in a Haiti Cohort
H. Mohri*1, T. Sakai1, N. Mushtaq1, D. Fitzgerald2,3, J. W. Pape2, W. D. Johnson1, D. D. Ho1
1Aaron Diamond AIDS Res Ctr, New York, NY; 2Groupe Haitien D'Etude du Sarcome de Kaposi et des Infections; Opportunistes, Port au Prince, Haiti; and 3Cornell Univ Med Coll, New York, NY
373Genetic Polymorphisms in DC-SIGNR Repeat Region Affect HIV-1 Transmission
H. Liu*1, M. J. McElrath1,2, S. Holte2, C. Celum1, J. Lee2, L. Corey1,2, T. Zhu1
1Univ of Washington, Seattle and 2Fred Hutchinson Cancer Res Ctr, Seattle, WA