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Session 47
Poster Presentations Immunology: NK Cell, Cytokine, and Innate Immune Responses Thursday 1:30 - 3:30 pm Hall D |
| 374 | Increased Natural Killer Cell Activity in HIV-1 Exposed but Uninfected Vietnamese Intravascular Drug Users D. Scott-Algara*1, L. X. Truong2, P. Versmisse1, A. David1, L. T. Tram2, N. V. Ngai3, I. Theodorou4, F. Barré-Sinoussi1, G. Pancino1 1Inst Pasteur, Paris, France; 2Inst Pasteur, Ho Chi Minh City, Vietnam; 3Hosp Binh Trieu, Ho Chi Minh City, Vietnam; and 4Hosp Pitié-Salpêtrière, Paris, France |
| 375 | Innate Immunity in HIV Infection: Effect of HIV Envelope-NK Cell Interactions S Kottilil*, K Shin, A M Planta, J Arthos, A S Fauci Lab of Immunoregulation, NIAID, NIH, Bethesda, MD |
| 376 | Enhancement of Natural Killer Cell Number and Cytokine-driven Activation in HIV-1+ Patients Recieving Growth Hormone and HAART M. Goodier*1, N. Imami1, G. Moyle2, L. Rennalls1, B. Gazzard2, F. Gotch1 1Imperial Coll Faculty of Med, Chelsea and Westminster Hosp, London, UK and 2Chelsea and Westminster Hosp, London, UK |
| 377 | Critical Role of NKp44L, the Ligand of the Activated Natural Cytotoxicity Receptor NKp44 in the CD4+ T-cells Depletion During HIV Infection V. Viellard*1, J. L. Strominger2, P. Debré1 1INSERM U543, Hosp Pitié-Salpétrière, Paris, France and 2Harvard Univ, Cambridge, MA |
| 378 | Tight Regulation of Primary Cytotoxic Response by Innate Helper Cells and its Impairment by Persisting Viruses I. M. Rouzine*1, K. Murali-Krishna2, R. Ahmed3 1Tufts Univ, Boston, MA; 2Univ of Washington, Seattle; and 3Emory Univ, Atlanta, GA |
| 379 | HIV Infection is Associated with Expanded Mucosal gamma delta T-cells, which may Explain Changes in Peripheral gamma delta T-cell Counts M. A. Poles*1,2, S. Barsoum1,2, P. Sun1, D. Ho2, L. Zhang2 1New York Univ Sch of Med, New York and 2Aaron Diamond AIDS Res Ctr, New York, NY |
| 380 | Local Delivery of CpG ODN Induces a Mucosal Innate Antiviral State and Prevents Genital HSV-2 Infection A. A. Ashkar, K. L. Rosenthal* McMaster Univ Hlth Sci Ctr, Hamilton, Canada |
| 381 | The Role of Cytokines which Signal through the Common Gamma Chain Cytokine Receptor in the Reversal of HIV-1 Specific CD4+ and CD8+ T-cell Anergy J. Gu, C. Kovacs, M. Ostrowski* Univ of Toronto, Canada |
| 382 | Association of Mannose-binding Lectin B Allele with Slower Progression to AIDS in Perinatally HIV-1 Infected Children but Not with HIV-1 Vertical Transmission A. Mangano*, D. Mecikovsky, S. Lusso, R. Bologna, L. Sen Hosp Natl de Pediatría "Prof Dr Juan P Garrahan," Buenos Aires, Argentina |
| 383 | Reductions of Serum Melatonin Levels in HIV-1 Infected Individuals Parallel Disease Progression: Correlation with Serum Interleukin-12 Levels G. Nunnari*1,2, L. Nigro2, F. Palermo2, D. Leto2, R. J. Pomerantz1, B. Cacopardo2 1Thomas Jefferson Univ, Philadelphia, PA and 2Univ of Catania, Italy |
| 384 | Comparison of the Efficacy of gp120-based Immunogens in Transgenic Mice Producing Human IgGs Y. He*, W. Honnen, S. C. Kayman, A. Pinter Publ Hlth Res Inst, Newark, NJ |
| 385 | Morphine Enhances HIV Infection of Human Blood Mononuclear Phagocytes through Modulation of C. J. Guo*, Y. Li, S. Tian, X. Wang, S. D. Douglas, W. Z. Ho Children's Hosp of Philadelphia, PA |
| 386 | Differential Regulation of IL-7 Receptor (CD127) by TNF A. Komsic*, C. D. Young, J. B. Angel Ottawa Hlth Res Inst, Ottawa, Canada |
| 387 | A Non-secreted Variant of Interleukin-4 is Associated with Apoptosis-Implication for Th2 Polarization in HIV Infection E. Ledru, M. Fevrier, H. Lecoeur, S. Garcia, S. Boullier , M.-L. Gougeon* Inst Pasteur, Paris, France |
| 388 | HIV Inhibition of IL-12 Synthesis is Mediated by Altering MAPK Activity and Nuclear Factor Binding to the IL-12p40 Promoter F. M. Frappier*, K. A. Chambers, J. B. Angel Ottawa Hlth Res Inst Univ of Ottawa, Canada |
| 389 | HIV gp120 and CD4 Binding Induces Activation of STAT1, STAT3, and STAT5 in Promonocytes and Macrophages J. Kohler*1, C. Gavegnano2, J. Sleasman1, M. Goodenow1 1Univ of Florida, Coll of Med, Gainesville and 2Univ of Florida, Gainesville |
| 390 | Increased Sensitivity of Peripheral Lymphocytes from HIV-1 Infected Individuals to CD4- and CXCR4-mediated Apoptosis E. Ritsou*1,2, R. Breitkreutz3, A. Benner2, T. Bohler4, M. A. Weigand5, H. Walczak2, M. L. Gougeon1, P. H. Krammer2 1Inst Pasteur, Paris, France; 2Div Med and Biological Informatics at the German Cancer Res Ctr, Heidelberg, Germany; 3Frankfurt Univ Hosp, Germany; 4MDK BW, Heidelberg, Germany; and 5Univ of Heidelberg, Germany |
| 391 | Increased hEKLF Levels in HIV-1 Infected Macrophages: A Differential Role for hEKLF in Regulating IL-12 p40 Promoter through Newly Identified CACCC Region and Modulation of the NFkB Pathway Q. Luo*1, X. Ma2, N. Ngoubilly1, S. Wahl3, J. Bieker4, M. Crossley5, L. J. Montaner1 1Wistar Inst, Philadelphia, PA; 2Weill Med Coll of Cornell Univ, New York, NY; 3Natl Inst of Hlth, Bethesda, MD; 4Mt Sinai Sch of Med, New York, NY; and 5Univ of Sydney, Australia |
| 392 | No Changes in Immune Activation Phenotypes, Response to Antigen, or CD8+ T-cell Mediated HIV Suppression in Transplant Recipients Receiving Immunosuppression M. Roland*1, D. Stablein2, B. Bredt1, B. Munoz-Marino1, L. Carlson1, J. McCune1, J. Levy1, R. Rogers1, P. Stock1 1Univ of California at San Francisco and 2EMMES Corp, Rockville, MD |
| 393 | Promoter Analysis of Early Response Genes Induced by Chemokine Receptor Signaling A. B. van 't Wout*, D. J. Westreich, H. He, D. C. Nickle, J. I. Mullins Univ of Washington, Seattle |
| 394 | Prostratin Induces Internalization and Degradation of HIV-specific Receptor and Co-receptor through Activation of Novel PKCs M. Hezareh*1, P. Dudognon2, M. Pondarzewski2, S. J. Brown1, J.-L. Carpentier2, M. Foti2 1AIDS Res Alliance, West Hollywood, CA and 2Ctr Med Univ, Geneva, Switzerland |
| 395 | HIV-1 Tat Reprograms Immature Dendritic Cells to Express Chemoattractants for Activated T-cells and Macrophages E. Izmailova1, F. Bertley1, Q. Huang2, N. Makori3,4, C. J. Miller3,4, R. A. Young2, A. Aldovini*1 1Children's Hosp, Harvard Med Sch, Boston, MA; 2Whitehead Inst for BioMed Res, Cambridge, MA; 3California Natl Primate Res Ctr, Davis, CA; and 4Univ of California at Davis |