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Session 53
Poster Presentations DNA Vaccines Thursday 1:30 - 3:30 pm Hall D |
| 447 | Enhanced DNA Prime-protein Boost Vaccines Induce Potent and Protective Immune Responses Against HIV-1 S. Barnett*1, I. Srivastava1, L. Stamatatos2, J. zur Megede1, Y. Lian1, G. Otten1, D. Montefiori3, M. Lewis4, S. Engelbrecht5, E Janse van Rensburg5, G Widera6, D O'Hagan1, J Polo1, J Ulmer1, J Donnelly1 1Chiron Corp, Emeryville, CA; 2Seattle BioMed Res Inst, WA; 3Duke Univ, Durham, NC; 4Southern Res Inst, Gaithersburg, MD; 5Univ of Stellenbosch, Tygerberg, South Africa; and 6Genetronics, Inc, San Diego, CA |
| 448 | Novel Forms of DNA Vaccines Decrease Viremia Upon SIVmac251 Challenge M. R. Rosati1, P. Carney1, A. von Gegerfelt1, A. Valentin1, E. Tryniszewska2, G. Franchini2, P. Markham3, D. Venzon2, N. Miller4, B. K. Felber1, G. N. Pavlakis*1 1Natl Cancer Inst, Frederick, MD; 2Natl Cancer Inst, Bethesda, MD; 3Advanced BioSci Labs, Inc, Kensington, MD; and 4Natl Inst of Allergy and Infectious Diseases, Bethesda, MD |
| 449 | Specific, Efficient, and Short-lived DNA Expression in Lymph Node Dendritic Cells Mediates DermaVir’s Immunotherapeutic Effects F Lori*1, J Trocio1, L Galluzzi1, P Markham2, C Fox3, J Lisziewicz1 1Res Inst for Genetic and Human Therapy, Washington, DC; 2Advanced BioSci Labs, Rockville, MD; and 3Univ of Arkansas, Little Rock |
| 450 | Vector Components and Intracellular Process that May Influence the Expression and Immunogenicity of Codon-optimized HIV-1 Env DNA Vaccines S. Wang*, D. Farfan, S. Shen, A. Hirsch, Y. Xing, F. He, T. Giehl, S. Lu Univ of Massachusetts, Worcester |
| 451 | Design, Purification, and Immunological Testing of DNA Vaccines against HIV-1 B.V. Murashev*, A. E. Masharsky, I. V. Murasheva, A. E. Romanovich, I. V. Dukhovlinov, M. S. Pavlova, Y. N. Dukhovlinova, Y. S. Dorofeyeva, Y. P. Galatchiants, N. A. Klimov, A. P. Kozlov BioMed Ctr, St Petersburg, Russia |
| 452 | The Effect of Single-site versus Multiple-site DNA vaccination on Immune Responses in Mice D. Gardiner*1,2,3, Y. Huang1,2, Z. Chen1,2, D. Gurner1,2, L. Leung1,2, Y. Song1,2, M. Tsuji1,2,4, D. Ho1,2 1Aaron Diamond AIDS Res Ctr, New York, NY; 2The Rockefeller Univ, New York, NY; 3Cornell Med Coll, New York, NY; and 4New York Univ |
| 453 | Effective Induction of Virus-specific Immunity Induced by Rectal or Nasal DNA-MVA Vaccination and its Effect on SHIV Challenge F. M. N. Bertley1, S. W. Wang1, P. Kozlowski1, A. Carville2, K. G. Mansfield2, R. P. Johnson2, J. Lifson3, A. Aldovini*1 1Children's Hosp, Harvard Med Sch, Boston, MA; 2New England Reg Primate Res Ctr, Southborough, MA; and 3Natl Cancer Inst, Frederick Cancer Res and Development Ctr, MD |
| 453a | Magnitude and Diversity of Cytotoxic T-lymphocyte Responses Elicited by Multiepitope DNA Vaccination in Rhesus Monkeys R A Subbramanian*, M J Kuroda, W A Charini, D H Barouch, C Costantino, S Santra, J E Schmitz, J W Shiver, N L Letvin Harvard Medical School, Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Boston, Massachusetts |