Search Abstracts Program


Session 58   Poster Presentations
Viral Replication and Pathogenicity
Thursday 1:30 - 3:30 pm
Hall A
476HIV-1 Infection Is Associated with Changes in Drug Transporter Gene Expression In Vivo
MP De Pasquale*, T. Hulgan, L. Sutton, W.F Carlisle, H. Erdem, M. Rueff, C. McGowan, R. Kim, J.P. Donahue, D. W. Haas, R.T. D’Aquila
Vanderbilt Univ Med Ctr, Nashville, TN
477Non-Replicating HIV-1 Virions Induce Increased Expression of Activation Markers in Primary T-cells in a Strain-dependent Manner
G. Holm*1,2, D. Gabuzda1,2
1Dana-Farber Cancer Inst, Boston, MA and 2Harvard Med Sch, Boston, MA
478HHV-7 Enhancement of HIV Replication in Human Lymphoid Explants
K.M. Duus*, Y. Zhang, L. Su, J. Webster-Cyriaque
Univ of North Carolina, Chapel Hill
479Influence of MDR1 on CD4+ Cell Permissiveness to HIV-1 Infection
G. Bleiber*, C. Suarez, R. Martinez, J. Fellay., C. Marzolini, A. Telenti
CHUV Lausanne, Switzerland
480SDF-1 Production by Dendritic Cells
M Bermejo*1, J L Pablos2, L Sanchez1, J Alcami1
1Inst de Salud Carlos III, Madrid, Spain and 2Hosp 12 de Oct Madrid, Spain
481EBV Infection can Enhance IL-7 Production and Up-regulate the Replication of HIV
Y. Okamoto*1, D. Douek1, G.B. Di Russo2, R.A. Koup1
1Vaccine Res Ctr NIH, Bethesda, MD and 2Children's Natl Med Ctr, Washington, DC
482The Two Predominant HIV-1 Variants in Africa, CRF02-AG and Subtype C, Have Different Biological Characteristics
Anke Bourgeois1, Eitel Mpoudi2, Florian Liegeois2, Rose Mognoutou2, Christian Laurent1, Eric Delaporte*1, Martine Peeters1
1UR36, IRD and Univ of Montpellier, France and 2Projet Prevention du Sida au Cameroun, Yaounde, Cameroon
483Early Extensive Viremia During SIVmnd-2 Infection in mandrillus sphinx is Associated with Transient Activation of Peripheral and Lymphnode T-cells
R Onanga*1, S Souquière1, M Makuwa1, F Simon2, F Barré-Sinoussi3, M C Müller-Trutwin3, P Roques1
1Ctr Intl de Res Med de Franceville, Gabon; 2Univ de Rouen, France; and 3Inst Pasteur, Paris, France
484Dysregulation of Chemokine and Dendritic Cell Networks in Lymphoid Tissues during Simian Immunodeficiency Virus Infection In Vivo: Mechanisms of Immunopathogenesis
Todd A. Reinhart*1, Beth A. Fallert1, Yang Kyu Choi1,2, Todd M Schaefer1, Sonali Sanghavi1, Michael A. Murphey-Corb1, Shrabani Basu1
1Univ of Pittsburgh, PA and 2Korea Res Inst of BioMed and Biotechnology, Yusong, Teajon, Korea
485HIV Superinfection in HIV+ Persons
T. Wong*1, S. Kravcik2, J. Angel2, T. Gleeson3, M. Montpetit3
1Hlth Canada and Univ Ottawa, Canada; 2Univ of Ottawa, Canada; and 3Canadian Molecular Res Services, Ottawa
486HIV-1 Superinfection with a CRF01_AE Strain: Cell-free RNA Levels are Significantly Lower than the Primary Infecting Subtype B Strain
S.Subbarao*1, A.Ramos1, P.Srinivasan1, D.Hu1, S.Vanichseni2, K.Choopanya2, T.Chaowanachan3, J.Tappero1,3, T.Mastro1, T.Folks1
1CDC, Atlanta, GA; 2Bangkok Metropolitan Admin, Thailand; and 3Thai Ministry of Publ Hlth -U S CDC Collaboration, Nonthaburi, Thailand
487Env is a Cytopathic Determinant of R5-AIDS HIV-1 in SCID-hu Mice
K. Olivieri*, R. Scoggins, A. Matthews, B. Brodick, J. Taylot, D. Chernauskas, D. Camerini
Univ of Virginia, Charlottesville
488Lymphocytes Isolated from Naturally SIV-infected Sooty Mangabeys Do Not Show Signs of Cell-cycle Perturbations or Increased Susceptibility to Apoptosis
B Cervasi*1, M Paiardini1, G Costantino2, B Sumpter1, H Radziewicz1, H McClure1, M Magnani3, G Piedimonte2, S O'Neill4, S Staprans1, MB Feinberg1, G Silvestri1
1Emory Univ, Atlanta, GA; 2Univ of Messina, Italy; 3Univ of Urbino, Italy; and 4New England Primate Ctr, Harvard Univ, Boston, MA
489The Second Exon of SIVmac239 Tat Contributes to Chronic Viral Replication and Disease
Stephen M. Smith*1,2, Zachary Klase1, Sara Pentlicky1, Christine Neuveut3, Preston Marx4, K.T. Jeang3
1St Michael's Med Ctr, Newark, NJ; 2New Jersey Med Sch, Newark, NJ; 3Natl Inst of Allergy and Infectious Diseases, NIH, Bethesda, MD; and 4Tulane Univ Sch of Med, Covington, LA
490The Intrinsic Difference in Susceptibility to AIDS-like Disease Induced by Simian Immunodeficiency Virus: Infection of Rhesus Macaques Is Associated with the Ability of Primary CD4+ Lymphocytes to Differentially Control Viral Reverse Transcription
A. Hartman*, P. Rajakumar, M. Murphey-Corb
Univ of Pittsburgh Sch of Med, PA
491Pathogenesis of R5 HIV-1 in Fetal Thymic Organ Culture
S Choudhary*1, K Kimbrell1, J Colasanti1, D Chernauskas 1, D Kwa2, H Schuitemaker2, D Camerini1
1Univ of Virginia, Charlottesville and 2Central Lab of the Red Cross Blood Transfusion Service (CLB), Amsterdam, The Netherlands
492Immunological and Virological Failure following Antiretroviral Therapy is Associated with Enhanced Thymic and Peripheral T-cell Pathogenicity
A Solomon1, P Cameron1, M Bailey2, A Dunne3, S Crowe3, J Hoy4, S Lewin*1
1Univ of Melbourne, Australia; 2Monash Univ, Melbourne, Australia; 3The Burnet Inst, Melbourne, Australia; and 4The Alfred Hosp, Melbourne, Australia