Search Abstracts Program


Session 59   Poster Presentations
Viral Genetic Diversity
Thursday 1:30 - 3:30 pm
Hall A
493Genetic Diversity of HIV-1 Populations in Infected Persons
S Palmer*1, F Maldarelli1, M Kearney1, S Kottilil2, D Lucey3, J Metcalf2, D Rock2, M VanHoutte4, L Michels4, K Hertogs4, J Mellors5, J Coffin1
1HIV Drug Resistance Prgm, NCI, NIH, Frederick, MD; 2Lab of Immunoregulation, NIAID, NIH, Bethesda, MD; 3Wash Hosp Ctr, Washington DC; 4VIRCO, Mechelen, Belgium; and 5Univ of Pittsburgh, PA
494HIV-1 Genetics of Intermittent Low-level Viremia
NH Tobin*1, Y Wang1, GH Learn1, JL McKernan1, GM Ellis1, KM Mohan1, SE Holte1, SM De Vange1, DM Pawluk1, AJ Melvin1, PL Lewis2, IA Beck1, M Mahalanabis1, JI Mullins1, LM Frenkel1
1Univ of Washington, Seattle and 2Oregon Hlth and Sci Univ, Portland
495Early HIV-1 Viral Diversity Associated with Rapid Disease Progression
Geoffrey S. Gottlieb*1, Mark A. Jensen1, David C. Nickle1, Kim G. Wong1, Fusheng Li1, Gerald H. Learn1, Joseph B. Margolick2, James I. Mullins1
1Univ of Washington, Seattle and 2Johns Hopkins Bloomberg Sch of Publ Hlth, Baltimore, MD
496Low Pretreatment Diversity of HIV-envelope Sequences in Chronically Infected Patients Predict Spontaneous Control of Plasma Viremia after Structured Treatment Interruptions
B. Joos*1, M. Fischer1, H. Kuster1, C. Leemann1, J. Böni2, A. Oxenius3, J. Wong4, D. Price5, R. Phillips5, B. Hirschel6, R. Weber1, A. Trkola1, H. Günthard for Swiss HIV Cohort Study
1Univ Hosp, Zurich, Switzerland; 2Natl Ctr Retroviruses, Zurich, Switzerland; 3Inst Microbiology ETH, Zurich, Switzerland; 4Univ of San Diego, CA; 5Univ of Oxford, UK; and 6Univ Hosp, Geneva, Switzerland
497Maintenance of the Complexity of the env Gene Populations during Fixation of a Drug Resistance Marker at High but Not Low HIV-1 RNA Load: A Potential Role for Recombination
K. M. Kitrinos*, J. A. E. Nelson, W. Resch, R. Swanstrom
Univ of North Carolina, Chapel Hill
498A Bioinformatic Predictor of Coreceptor Usage Correlates with Markers of Disease Progression and Supports the Gradual Evolution of X4 Virus via R5X4 Intermediates
M. Jensen*1, G. Gottlieb1, A. van 't Wout1, F.-S. Li2, D. Nickle1, D. Shriner1, K. Wong1, H.-X. He1, S. McLaughlin1, R. Shankarappa3, J. Margolick4, J. Mullins1
1Univ of Washington, Seattle; 2Primal Inc, Seattle, WA; 3Allegheny-Singer Res Inst, Pittsburgh, PA; and 4Johns Hopkins Sch of Hygiene and Publ Hlth, Baltimore, MD
499Compartment-specific Patterns Associated with CSF-derived V3 Sequences
Benjamin Good1, Satish Pillai*2, Jacques Corbeil2, Joseph Wong2
1Veterans Med Res Fndn, San Diego, CA and 2Univ of California at San Diego
500High Diversity of Cell-associated Reservoirs of HIV-1 May Contribute to Viral Genetic Shifts in the Plasma
T. Liegler*1, J. Harris2, M. Warmerdam1, J. Barbour1, L. J. Montaner3, J. M. McCune1, R. M. Grant1
1J D Gladstone Inst of Virology and Immunology, San Francisco, CA; 2Univ of California at San Francisco; and 3Wistar Inst, Philadelphia, PA
501SIVcpz Prevalence and Genetic Diversity in Wild Communities of Eastern Chimpanzees
M. Santiago*1, M. Lukasik 2, S. Kamenya 2, Y. Li 1, F. Bibollet-Ruche 1, D. Goldenberg3, M. Muller 4, M. Emery4, D. Watts 3, R. Wrangham 4, A. Pusey 5, D. Collins 2, J. Goodall 6, G. Shaw 7, B. Hahn 1
1Univ of Alabama at Birmingham; 2Gombe Stream Res Ctr, Kigoma, Tanzania; 3Yale Univ, New Haven, CT; 4Harvard Univ, Cambridge, MA; 5Univ of Minnesota, St Paul; 6Jane Goodall Inst, Silver Springs, MD; and 7Howard Hughes Med Inst, Univ of Alabama at Birmingham, AL