Search Abstracts Program


Session 65   Poster Presentations
Pharmacology of Novel Antiretroviral Agents
Wednesday 1:30 - 3:30 pm
Hall A
546-AThe Preclinical Pharmacokinetics and Safety Pharmacology of the Anti-HIV CCR5 Antagonist, UK-427, 857
C. Napier*1, P. Dorr1, R. Gladue2, R. Halliday1, D. Leishman1, I. Machin1, R. Mitchell1, A. Nedderman1, M. Perros1, S. Roffey1, D. Walker1, R. Webster1
1Pfizer Global R&D, Sandwich Labs, Kent, UK and 2Pfizer Global R&D, Groton Labs, CT
547Pharmacokinetics of Single and Multiple Oral Doses of UK-427,857-A Novel CCR5 Antagonist in Healthy Volunteers
S. Abel*, E. Van der Ryst, G. J. Muirhead, M. Rosario, A. Edgington, G. Weissgerber
Pfizer Global Research and Dev, Sandwich Labs, Kent, UK
549TMC114, A Next Generation HIV Protease Inhibitor: Pharmacokinetics and Safety Following Oral Administration of Multiple Doses With and Without Low Doses of Ritonavir in Healthy Volunteers
R. Hoetelmans*1, I. Van der Sandt2, M. De Pauw1, K. Struble3, M. Peeters1, R. Van der Geest1
1Tibotec, Mechelen, Belgium; 2Kinesis, Breda, The Netherlands; and 3Tibotec-Virco, Durham, NC
549aQuality-Control Analysis of Generic Nevirapine Formulations in the Developing World: An Initial Report
S Penzak1, J Tavel*2, E Acosta3, M Turner3, H Masur1
1Clin Ctr, NIH, Bethesda, MD; 2NIAID, NIH, Bethesda, MD; and 3Div Clin Pharmacol, UAB, Birmingham, AL