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Session 38
Poster Presentations Virus Life Cycle: Transcriptional Regulation, Integration, RNA Packaging, and Reverse Transcription Wednesday 1:30 - 3:30 pm Hall D |
| 232 | Identification of a Potent Inhibitor of HIV-1 Rev Function Jodi Bubenik*, Alan Cochrane Univ of Toronto, Canada |
| 233 | DDX1, a Putative RNA Helicase, Is a Cellular Co-factor of the NIS Domain of HIV-1 REV jianhua fang*1, Satoshi Kubota1, Roseline Godbout2, Roger J Pomerantz1 1Thomas Jefferson Univ, Philadelphia, PA and 2Univ of Alberta, Canada |
| 234 | High Cell Type-dependent Rate of Recombination by HIV-1 But Not By Non-diversifying Retroviruses D. N. Levy*1, G. M. Shaw1,2 1Univ of Alabama at Birmingham and 2Howard Hughes Med Inst, Birmingham, AL |
| 235 | The High Frequency of HIV-1 Recombination Leads to the Efficient Generation of Mosaic HIV-1 Genome J. Zhuang*1, A. Jetzt1,2, Y. Ron1, B. Preston3, J. Dougherty1 1Univ of Med and Dentistry in New Jersey (UMDNJ), Robert Wood Johnson Med Sch, Piscataway, NJ; 2Rutgers Univ, New Brunswick, NJ; and 3Univ of Washington, Seattle |
| 236 | Identification and Characterization of a Simian Immunodeficiency Virus Reverse Transcriptase High-fidelity Mutation, V148I, Identified After Infection of a Macaque with a Low-fidelity Reverse Transcriptase-containing Virus T.L. Diamond*, G. Souroullas, K.K. Weiss, K.Y. Lee, R. A. Bambara, S. Dewhurst, B. Kim Univ of Rochester, NY |
| 237 | Identification of a Strong, Discrete Encapsidation Determinant in a 230 nt Segment of Feline Immunodeficiency Virus Gag Explains Preferential Encapsidation of Full-length Viral mRNA Iris Kemler, Ishara Azmi, Roman Barraza, Eric M. Poeschla* Mayo Med Sch, Rochester, MN |
| 238 | Novel Integrase Determinants Required for Efficient Initiation of HIV-1 DNA Synthesis M. Padow*1, L. Lai1, K. Zammit1, B. Weiss2, D. Dunn2, X. Wu1, J. C. Kappes1 1Univ of Alabama at Birmingham and 2Univ of Utah, Salt Lake City |
| 239 | Characterization of the Subcellular Distributions of FIV and HIV-1 Integrase M. Vanegas*, M. Llano, E. Poeschla Mayo Med Sch, Rochester, MN |
| 240 | Markedly Cell Cycle-dependent Expression Phenotypes of Class I Integrase Mutants of 2 Lentiviruses (FIV, HIV-1): Wild-type Expression Levels from Unintegrated Lentiviral Vector DNA in Non-dividing Cells Dyana T. Saenz*, Nils Loewen, David Leske, Margaret Good, Jonathan Holmes, Eric M. Poeschla Mayo Med Sch, Rochester, MN |
| 241 | SUMO-1, Ubc9, and HIV-1 Integrase Function L. Berthoux*1, C. Gurer1, D. Sayah1, Y-C. Han1, L. Mulder2, M. Muesing2, J. Luban1 1Columbia Univ, New York, NY and 2Aaron Diamond AIDS Res Ctr, Rockefeller Univ, New York, NY |
| 242 | HIV-1 DNA Content does not Correlate with Integration Frequency in Patient-derived PBMCs W Swiggard*, J Yu, D McGain, U O'Doherty Univ of Pennsylvania, Philadelphia |
| 243 | Identification of Key Cellular Factors Essential for HIV-1 Replication that Interact with HIV-1 Integrase, Protease, and Reverse Transcriptase: Novel Targets for Anti-HIV-1 Drug Discovery S. Emiliani1, J.C. Rain2, E. Segeral1, F. Moisant2, N. Heveker1, P. Legrain2, R. Benarous*1 1Inst Cochin, Paris, France and 2Hybrigenics S A, Paris, France |
| 244 | Temporal Modulation of Monocyte-Derived Macrophage Gene Expression during HIV-1 Infection C. H. Woelk*, F. Ottones, C. D. Royer, C. R. Plotkin, S. E. Rought, J. Lozach, R. Sasik, J. Corbeil,, 1Univ of California at San Diego, La Jolla; Veterans Med Res Fndn, San Diego, CA; and San Diego Veterans Affairs Med Ctr, La Jolla, CA |
| 245 | Differential Gene Expression in Chronically HIV-1 Infected Monocyte-derived Macrophages A. Meehan*, M. Llano, M. Peretz, S. Raghavakaimal, M. Charleton, E. Poeschla Mayo Med Sch, Rochester, MN |
| 246 | Towards to Depletion of Resting CD4 Cell Reservoir of HIV-1 David M. Margolis1,2, Loyda Ylisastigui1, Holly Johnson*1 1Univ of Texas Southwestern Med Ctr, Dallas and 2North Texas Veterans Hlth Care Sys, Dallas |
| 247 | Reactivation of Latent HIV-1 Infection by Activating Antibodies and Recombinant Proteins Targeting Costimulatory Molecules Olaf Kutsch*, David N. Levy, George M. Shaw, Etty N. Benveniste Univ of Alabama at Birmingham |
| 248 | Analysis of Gene Expression from HIV 2-LTR Circles in Primary Human Antigen Presenting Cells T Cunningham*1, L Smith1, M Pope2, M A Muesing1 1Aaron Diamond AIDS Res Ctr, Rockefeller Univ, New York, NY and 2Pop Council, Ctr for BioMed Res, New York, NY |
| 249 | Caveolin-1 Blocks HIV-1 Expression Post-transcriptionally Manuel Llano*, Mary Peretz, Maria Vanegas, Eric Poeschla Mayo Clin Rochester, MN |
| 250 | OTK18 Binds to Regulatory Elements of HIV-1 LTR and Regulates Transcriptional Activity M. Horiba *, J. Limoges, J. Buescher , G. Pohlman , H.E. Gendelman , T. Ikezu Ctr for Neurovirology, UNMC, Omaha, NE |
| 251 | Role of Structured Regions within the R-U5 Intron of Simian Immunodeficiency Virus in RNA Packaging and Dimerization J. B. Whitney*, B. Spira, M. A. Wainberg McGill AIDS Ctr, Montreal, Canada |
| 252 | Recovery of Fitness of an Attenuated Simian Immunodeficiency Virus through Compensation in Coding and Non-coding regions. James B. Whitney*, Bonnie Spira, Mark A. Wainberg McGill AIDS Ctr, Montreal, Canada |
| 253 | RNA Incorporation is Critical for Retroviral Particle Stability after Release but Not for Particle Assembly S.W. Wang*,1, A. Aldovini,1 1 and 1Children's Hosp and Harvard Med Sch, MA |
| 254 | The Involvement of RNA Sequences Downstream of the Major Splice Donor Site in HIV-1 RNA Dimerization and Packaging R.S. Russell*, J. Hu, B. Spira, M.A. Wainberg, C. Liang McGill AIDS Ctr, Lady Davis Inst, Jewish Gen Hosp, Montreal, Canada |
| 255 | RNA:RNA Junctions in Dimeric RNAs Isolated from Immature and Mature Murine Leukemia Virus Particles C. Hibbert*, J. Mirro, A. Rein Natl Cancer Inst, Frederick, MD |
| 255b | Molecular Characterization, Reactivation and Depletion of Latent HIV D H Hamer*1, D G Brooks2, P A Arlen2, L Gao2, G Bristol2, E A Berger3, J A Zack2 1NCI, Bethesda, MD; 2UCLA, Los Angeles, CA; and 3NIAID, Bethesda, MD |