Search Abstracts Program


Session 94   Poster Presentations
Pathogenesis and Mechanisms of Lipodystrophy Syndromes
Thursday 1:30 - 3:30 pm
Hall B
753Mechanism of Dyslipidaemia in HIV-infected Adults
S. Das*1, M. Stolinski2, W. Jefferson2, N. Jackson2, G. Gilleran3, R. Cramb4, M. Umpleby5, M. Shahmanesh6
1Specialist Registrar, Birmingham, UK; 2Res Fellow, London, UK; 3Res Nurse, Birmingham, UK; 4Consultant Endocrinologist, Birmingham, UK; 5Reader, Human Metabolism, London, UK; and 6Consultant Physician, Birmingham, UK
754Serum Adipocytokines are Related to Lipodystrophy and Metabolic Alterations in HIV-infected Men Under PI-Based HAART
C. Vigouroux1,2, M. Maachi1,2, T-H. Nguyen1, C. Coussieu3, S. Gharakhanian1, T. Funahashi4, Y. Matsuzawa4, I. Shimomura4, W. Rozenbaum1, J. Capeau*1,2, J-P. Bastard1,2
1Tenon Hosp, Paris, France; 2INSERM U 402, Paris, France; 3Hôtel-Dieu Hosp, Paris, France; and 4Osaka Univ, Japan
755Effects of HAART on Expression (mRNA) of PPAR-gamma, UCP2, UCP1, Mitochondrial DNA Depletion and Proliferation
C. Pace1, A. Martin1, C. Mamotte2, E.Hammond*1, D. Nolan1, S. Mallal1
1Ctr for Clin Immunology and BioMed Statistics, Western Australia and 2Royal Perth Hosp, Australia
756Adipocytokine Levels in the Lipodystrophy Syndrome of HIV-infected Patients
W. L. Dinges*1, D. Chen1, I. Shimomura2, Y. Matsuzawa2, D. M. Peterson1, A. Garg1
1Univ of Texas Southwestern Med Ctr, Dallas and 2Osaka Univ, Japan
757Impaired Insulin Sensitivity in HIV-infected Individuals is Associated with Higher Hepatic Lipid Content and Visceral Adiposity
K. Yarasheski*, D. Reeds, J. Schulte, E. Zinna, S. Claxton, S. Mohammed, D. Yablonskiy, L. Bretthorst, W. Powderly, S. Klein
Washington Univ, St Louis, MO
758Impaired Gene Expression in Adipose Tissue of HIV Subjects Undergoing HAART, Affected by Severe Lipodystrophy
A. Napolitano*, I. Marchetti, R. Guttmann, P. Ferrari, J. L. Sadoul, P. Dellamonica, J. Durant
CHU Archet, Nice, France
759Evidence of Toxicity in Adipose Tissue of HIV-infected Patients Correlates with NRTI-associated mtDNA Depletion
E. Hammond*1, D. Nolan1, I. James1, E. McKinnon1, A. White2, S. Mallal1
1Ctr for Clin Immunology and BioMed Statistics, Western Australia and 2GlaxoSmithKline, UK
760Evaluation of the Oxidative Metabolism in Skeletal Muscle Using Carbon-11 Acetat PET in HIV-infected Patients with Lipodystrophy Syndrome
G. M. N. Behrens*1,2, A-R. Boerner1, K. Weber1, J. van den Hoff1, J. Ockenga1, G. Brabant1, R. E. Schmidt1
1Hannover Med Sch, Germany and 2Walter and Eliza Hall Inst, Melbourne, Australia
761Absence of Sustained Hyperlactatemia Among HIV-infected Patients with Risk Factors for Mitochondrial Toxicity
D. A. Wohl*1, C. D. Pilcher1, M. Revuelta2, G. McComsey 3, S. L. Koletar 4, S. Evans 5, Y. Yijun 5, R. Zackin 5, B. Alston 6, S. Welch 7, M. Basar8, A. Kashuba1, P. Kondo9, J. Quinn 10, H. Wingfield11
1Univ of North Carolina, Chapel Hill; 2Beth Israel Med Ctr, New York, NY; 3Case Western Reserve Univ, Cleveland, OH; 4Ohio State Univ, Columbus; 5Harvard Sch of Public Hlth, Boston, MA; 6Natl Inst of Hlth, Bethesda, MD; 7Social and Sci Sys, Silver Spring, MD; 8Frontier Sci and Tech Res Fndn, Amherst, NY; 9Univ of Hawaii, Honolulu; 10Univ of Pennsylvania, Philadelphia; and 11Univ of Alabama at Birmingham
762Mitochondrial Membrane Potential and HAART-associated Lactic Acidosis
P. V. Nerurkar*, L. Pearson, J. E. Frank, R. Yanagihara, V. R. Nerurkar
Univ of Hawaii, Honolulu
763Evidence Suggesting Mitochondrial Toxicity in HIV/HCV Co-infected Patients Receiving Ribavirin and Didanosine
R. Fleischer*1, D. Boxwell1, K. E. Sherman2
1FDA, Rockville, MD and 2Univ of Cincinnati, OH
764Bone Loss Is Closely Related to Fat Loss in HIV-infected Patients Receiving Antiretroviral Treatment
G. Tsekes*1, D. Paraskeva1, G. Douskas2, M. Chini1, N. Mangafas1, M. Boboli1, E. Georgiou3, M. C. Lazanas1
1Red Cross Hosp, Athens, Greece; 2Hygias Melathron, Athens, Greece; and 3Athens Univ Med Sch, Greece