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Session 100   Poster Abstracts
Dyslipidemias and Body Fat Abnormalities: Incidence, Risk Factors, Response to Therapy
Monday, 1:30 - 3:30 pm
Poster Hall
712
Predictors of Low HDL in HIV+ Patients: Effect of Class of Antiretroviral Therapy and Traditional Risk Factors (CPCRA 065)
F Drummond*1, C Mullin2, M Poehlman2, and SMART Protocol Team and the Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA 065)
1Univ. of New South Wales, Sydney, Australia and 2Univ. of Minnesota, Minneapolis, USA
713
Determinants of Hyperlipidemia in ART-naive Subjects Treated with Trizivir, Combivir/Nelfinavir, or Stavudine/Lamivudine
P Kumar*1, V Williams2, K Tahima3, A Rodriquez-French4, M Thompson5, P Wannamaker2, J Hernandez2, and K Pappa2
1Georgetown Univ. Med. Ctr., Washington DC, USA; 2GlaxoSmithKline, Research Triangle Park, NC, USA; 3The Miriam Hosp., Providence, RI, USA; 4San Fernando Hosp., Panama City, Panama; and 5ARCA, Atlanta, GA, USA
714
Predictive Factors of Hyperlipidemia in HIV-infected Subjects Receiving Lopinavar/Ritonavir
M Bongiovanni1, P Cicconi1, S Landonio2, P Meraviglia2, L Testa3, A Di Biagio4, M Volpi1, E Chiesa1, M Schiavini2, S Melzi1, F Tordato1, M Moroni1, T Bini1, and A d'Arminio Monforte*1
1Inst. of Infectious Diseases and Tropical Med., Univ. of Milan, Italy; 2L. Sacco Hosp., Milan, Italy; 3Busto Arsizio Hosp., Varese, Italy; and 4Clin. Infectious Diseases, Univ. of Genoa, Italy
715
The Effects of Enfuvirtide Therapy on Body Composition and Serum Lipids through 48 Weeks in the TORO Trials
D A Cooper*1, P Reiss2, K Henry3, M Nelson4, M O'Hearn5, P Piliero6, J Reynes7, K Arasteh8, J Chung9, D Guimaraes9, T Kinchelow9, A Bertasso9, and the TORO 1 and TORO 2 study groups
1Natl. Ctr. in HIV Epidemiology and Clin. Res., Univ. of New South Wales, Sydney, Australia; 2Academic Med. Ctr., Amsterdam, The Netherlands; 3Hennepin County Med. Ctr., Minneapolis, MN, USA; 4Chelsea and Westminster Hosp., London, UK; 5Oregon Hlth. and Sci. Univ., Portland, USA; 6Albany Med. Coll., NY, USA; 7Hosp. Gui de Chauliac, Montpellier, France; 8EPIMED c/o Vivantes Auguste-Viktoria-Klinikum, Berlin, Germany; and 9Roche, Nutley, NJ, USA
716Toxicity and Efficacy of 3TC/EFV Associated with Stavudine or Abacavir in Antiretroviral-naive Patients: 48-week Results of a Randomized Open and Multicenter Trial (ABCDE Study)
D Podzamczer*1, E Ferrer1, P Sanchez1, J M Gatell2, M Crespo3, M Lonca2, J Sanz4, J Niubo1, S Veloso5, J M Llibre6, P Barrufet7, A Salas8, E Merino9, J Martinez-Lacasa10, L del Rio11, and ABCDE Study Team
1Hosp. Univ. de Bellvitge. L'Hospitalet, Barcelona, Spain; 2Hosp. Clin., Barcelona, Spain; 3Hosp. Vall d'Hebron. Barcelona.; 4Hosp. Principe de Asturias. Alcala de Henares. Madrid; 5Hosp. Joan XIII. Tarragona; 6Hosp. Sant Jaume de Calella. Calella; 7Hosp. de Mataro. Mataro; 8Hosp. Son Dureta. Palma de Mallorca; 9Hosp. Gen. de Alicante; 10Hosp. Mutua de Terrassa. Terrassa; and 11CETIR, Barcelona, Spain
717
Lipid Abnormalities and Body Habitus in a Double-blind, Randomized, Controlled Trial Comparing Emtricitabine to Stavudine in HIV+ ART-naive Patients
W Powderly*1, P Cahn2, F Raffi3, M Saag4, A Shaw5, J Hinkle5, E Mondou5, J B Quinn5, and F Rousseau on behalf of the FTC-301A Study Team5
1Washington Univ. Sch. of Med., St. Louis, MO, USA; 2Fndn. Huesped, Buenos Aires, Argentina; 3CHU Nantes, France; 4Univ. of Alabama at Birmingham, USA; and 5Gilead Sci., Inc., Durham, NC, USA
718Fat Redistribution and Metabolic Study (FRAMS) in Patients Receiving a Nucleoside Reverse Transcriptase Inhibitor, non-NRTI, or Protease Inhibitor-based Regimen over 4 Years: FRAMS II Substudy of the Atlantic Study
R Murphy*1, C Katlama2, G-J Weverling3, F Hoff1, R Roubenoff4, B Berzins1, J Gatell5, A Horban6, A van Eeden7, F Antunes8, E Bijleveld3, B Clotet9, S Staszewski10, R van Leeuwen3, J Lange3, and Atlantic Study Team
1Northwestern Univ., Chicago, IL, USA; 2Hosp. Pitie-Salpetriere, Paris, France; 3Intl. Antiviral Therapy Evaluation Ctr., Amsterdam, The Netherlands; 4Tufts Univ., Boston, MA, USA; 5Hosp. Clin., Barcelona, Spain; 6Wojewodzki Szpital Zakazny, Warsaw, Poland; 7Jan van Goyenkliniek, Amsterdam, The Netherlands; 8Hosp. Santa Maria, Lisbon, Portugal; 9Hosp. Univ. Germans Trias I Pujol, Barcelona, Spain; and 10Klinikum der Johann Wolfgang Goethe Univ., Frankfurt, Germany
719
Lipodystrophy and Dyslipidemia among Patients Taking HAART: First Study from India
S Pujari*1,2, A Patel3, A Dravid1,4, N Gupte4, S Bhagat1, E Naik2, A Mane1, and K Patel3
1Ruby Hall Clin., Pune, India; 2Univ. of South Florida, Tampa, USA; 3Sterling Hosp., Ahmedabad, India; and 4Pune, India
720
Lipid Profiles of Patients Enrolled in the MaxCmin 2 Trial: A Randomized, Open-label Multi-center Comparative Trial Evaluating the Safety and Efficacy of Lopinavir/Ritonavir (400/100 mg Twice Daily) vs Saquinavir/Ritonavir SQV/r (1000/100 mg Twice Daily)
S L Walmsley*1, J Benetucci2, A Brutus3, N Clumek4, U B Dragsted5, B Gazzard6, N Obel7, P Vernazza8, Z Fox5, J D Lundgren5, and on behalf of the MaxCmin 2 Trial Group
1Univ. of Toronto, Canada; 2FUNDAI, Buenos Aires, Argentina; 3Brookdale Univ. Hosp., Brooklyn, NY, USA; 4Ctr. Hosp. Univ. Sainte-Pierre, Brussels, Belgium; 5Hvidovre Univ. Hosp., Copenhagen, Denmark; 6Chelsea and Westminster Healthcare Trust, London, UK; 7Odense Univ. Hosp., Denmark; and 8Kantonsspital, St Gallen, Switzerland
721
Risk of Lipoatrophy in Antiretroviral-naive HIV-infected Adults: A Prospective Cohort Study with Objective Measurements of Limb Fat
E Martinez*1, A Milinkovic1, P Domingo2, M C Gomila2, S Vidal1, R Casamitjana1, M Larrouse1, J L Blanco1, J Mallolas1, F Garcia1, J M Miro1, and J M Gatell1
1Hosp. Clin., Barcelona, Spain and 2Hosp. de Sant Pau, Barcelona, Spain
722Baseline Triglyceride Levels Predict Development of Lipoatrophy in Patients Treated with Stavudine Extended-release/Prolonged-release Capsules or Stavudine Immediate-release
M Noor1, C Dezii*1, C McLaren2, V Wirtz2, J Maa1, L Bessen3, and S Hodder1
1Bristol-Myers Squibb, Virology Med. Affairs, Plainsboro, NJ, USA; 2Bristol-Myers Squibb Pharm. Res. Inst., Wallingford, CT, NJ, USA; and 3Bristol-Myers Squibb Pharm. Res. Inst., Princeton, NJ, USA
723A Prospective, Multi-center, Randomized Trial Comparing the Efficacy and Safety of Fenofibrate vs Pravastatin in HIV-infected Subjects with Lipid Abnormalities: Final Results of ACTG 5087
J A Aberg1, R A Zackin*2, S R Evans2, Y Yang2, B L Alston3, W K Henry4, M J Glesby5, SW Brobst3, S I Owens6, C J Fichtenbaum7, and ACTG 5087 Team
1Washington Univ., St. Louis, MO, USA; 2Harvard Sch. of Publ. Hlth., Boston, MA, USA; 3NIAID, NIH, DHHS, Bethesda, MD, USA; 4Univ. of Minnesota, Minneapolis, USA; 5Cornell Univ., New York, NY, USA; 6Frontier Sci. and Technology Res. Fndn., Amherst, NY, USA; and 7Univ. of Cincinnati, OH, USA
724
A Randomized, Open-label Clinical Trial of Omega-3-Fatty Acid (Fish Oil) Supplementation along with Diet and Exercise in HIV-infected Patients with Hypertriglyceridemia
D A Wohl*, C Cunningham, H-C Tien, B McIntosh, K Donovan, S-Y Leu, and R J Simpson Jr
Univ. of North Carolina at Chapel Hill, USA
725
Oxymetholone for the Treatment of HIV Wasting: A Double-blind, Randomized, Placebo-controlled Phase 3 Trial in Eugonadal Men and Women
U R Hengge*1, K Stocks2, S Faulkner3, H Wiehler2, C Lorenz4, W Jentzen5, A Mirmohammadsadegh6, D Hengge7, and G Ringham3
1Univ. of Düsseldorf, Germany; 2Univ. of Essen STD Unit, Germany; 3Unimed Pharm. Inc., Deerfield, IL, USA; 4Hosp. Pharmacy, Univ. of Essen, Essen, Germany; 5Univ. of Essen, Germany; 6Joachim Kuhlmann AIDS Fndn., Essen, Germany; and 7Univ. of Bonn, Germany
726
Treatment of Facial Lipoatrophy with Injections of Polylactic Acid in HIV-infected Patients: Results from a Cohort of 94 Patients
M Lafaurie, M Dolivo, D Boulu, H Finel, R Porcher, I Madelaine, A Furco, J Pavie, N Decastro, and J M Molina*
Saint Louis Hosp., Paris, France
727
Evaluation of Ultrasound for Assessing Facial Lipoatrophy in a Randomized, Placebo-controlled Trial
D Carey*1, H Wand1, A Martin1, S Emery1, A Carr2, D Cooper1,2, and the ROSEY Study Group
1Univ. of New South Wales, Sydney, Australia and 2St. Vincent's Hosp., Sydney, Australia