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Session 17   Oral Abstracts
Complications of HIV Infection and Antiretroviral Therapy
Tuesday, 10 am - 12:45 pm
Room 3000
Moderators Jens Lundgren
Copenhagen HIV Prgm, Hvidovre Univ Hosp, Denmark
Steve Grinspoon
Harvard Med Sch, Massachusetts Gen Hosp, Boston, MA, USA
10:00 am       72Population Prevalence of Hepatic Steatosis among Antiretroviral-experienced HCV/HIV Co-infected Adults with and without Stavudine Exposure
M Sulkowski*, S Mehta, R Moore, M Torbenson, R Chaisson, J Astemborski, and D Thomas
Johns Hopkins Univ., Baltimore, MD, USA
10:15 am       73Prevalence and Incidence of Pre-diabetes and Diabetes in the Multicenter AIDS Cohort Study
T T Brown*1, S R Cole1, X Li1, L A Kingsley2, F J Palella Jr3, S A Riddler2, B R Visscher4, J B Margolick1, and A S Dobs1
1Johns Hopkins Univ., Baltimore, MD, USA; 2Univ. of Pittsburgh, PA, USA; 3Northwestern Univ., Chicago, IL, USA; and 4Univ. of California, Los Angeles, USA
10:30 am       74Prospective Study of Glucose and Lipid Metabolism in Antiretroviral-Naive Subjects Randomized to Receive Nelfinavir, Efavirenz, or Both Combined with Zidovudine+Lamivudine (ZDV+3TC) or Didanosine+Stavudine: A5005s, a Substudy of ACTG 384
M Dubé*1, R Zackin2,3, R Parker2,3, Y Yang2,3, S Grinspoon3, P Tebas4, G Robbins3, R Shafer5, S Snyder6, K Mulligan7, and Adult AIDS Clinical Trials Group
1Indiana Univ, Indianapolis, IN, USA; 2Statistical and Data Analysis Ctr., Boston, MA, USA; 3Harvard Univ., Boston, MA, USA; 4Washington Univ., St. Louis, MO, USA; 5Stanford Univ., Palo Alto, CA, USA; 6ACTG Operations Ctr., Silver Spring, MD, USA; and 7Univ. of California, San Francisco, USA
10:45 am       75Predictors of Hypertension and Changes in Blood Pressure in HIV-infected Patients in the D:A:D Study
R Thiébaut*1, W El-Sadr2, G Chenuc1, N Friis-Moller3, M Rickenbach4, P Reiss5, A D’Arminio Monforte6, L Morfeldt7, C Pradier8, O Kirk9, S De Wit10, G Calvo11, M Law12, C Sabin13,14, J D Lundgren3, and D:A:D Study group
1Aquitaine Cohort, C.H.U. Bordeaux, INSERM U593, Bordeaux, France; 2CPCRA, Columbia Univ./Harlem Hosp., New York, NY, USA; 3Copenhagen HIV Prgm., Hvidovre Univ. Hosp., Denmark; 4SHCS, Ctr. Hosp. Univ. Vaudois, Lausanne, Switzerland; 5ATHENA, HIV Monitoring Fndn., Academic Med. Ctr., Amsterdam, The Netherlands; 6ICONA, L Sacco Hosp., Univ. of Milan, Milan, Italy; 7HivBivus, Karolinska Hosp., Stockholm, Sweden; 8Nice Cohort, CHU Nice Hosp. de l'Archet, France; 9EuroSIDA, CHIP, Hvidovre Univ. Hosp., Copenhagen, Denmark; 10Saint-Pierre Cohort, CHU Saint-Pierre Hosp., Brussels, Belgium; 11BASS, Autonomous Univ. of Barcelona, Spain; 12AHOD, Natl. Ctr. in HIV Epidemiology and Clin. Res., Sydney, Australia; 13Royal Free Ctr. for HIV Med., Royal Free and Univ. Coll., London, UK; and 14Univ. Coll. London, UK
11:00 am       76Nucleoside Reverse Transcriptase Inhibitors Decrease Mitochondrial and PPARgamma Gene Expression in Adipose Tissue after only 2 Weeks in HIV-uninfected Healthy Adults.
P Mallon*1,2, P Unemori1, M Bowen2, J Miller3, M Winterbotham1, A Kelleher1,2, K Williams2, D Cooper1,2, and A Carr2
1Natl. Ctr. in HIV Epidemiology and Clin. Res., Univ. of New South Wales, Sydney, Australia; 2St. Vincent’s Hosp., Sydney, Australia; and 3Garvan Inst. of Med. Res., Sydney, Australia
11:15 am       77 Effects of Pravastatin on Lipoproteins and Endothelial Function in Patients Receiving HIV Protease Inhibitors
J Sosman*, M Merwood, J Bellehumeur, S Aeschlimann, C Korcarz, G Underbakke, M Mays, and J Stein
Univ. of Wisconsin Med. Sch., Madison, USA
11:30 am       78Metabolic Changes in Patients Switching from a Protease Inhibitor-Containing Regimen to Abacavir, Efavirenz,) or Nevirapine: 24-Month Results of a Randomized Study
C Fisac*1, E Fumero1, M Crespo3, B Roson1, N Virgili1, E Ribera3, E Ferrer1, J M Gatell4, and D Podzamczer1
1Hosp. Univ. de Bellvitge, L'Hospitalet, Barcelona, Spain; 3Hosp. Vall d'Hebron, Barcelona, Spain; and 4Hosp. Clin., Barcelona, Spain
11:45 am       79Rosiglitazone for the Treatment of HIV Lipoatrophy: A Double-blind, Placebo-controlled, 48-week Trial
A Carr*1, C Workman2, G Rogers3, A Martin4, D Carey4, D Baker5, H Wand4, M Law4, K Samaras1,6, S Emery4, D Cooper4, and ROSEY study group
1St. Vincent's Hosp., Sydney, Australia; 2AIDS Res. Initiative, Sydney, Australia; 3Care and Prevention Gen. Practice, Adelaide, Australia; 4Natl. Ctr. in HIV Epidemiology and Clin. Res., Univ. of New South Wales, Sydney, Australia; 5407 Doctors, Sydney, Australia; and 6Garvan Inst. of Med. Res., Sydney, Australia
12:00 pm       80Low-dose Maintenance Therapy with Recombinant Human Growth Hormone Sustains Effects of Previous r-hGH Treatment in HIV+ Patients with Excess Center Fat: Treatment Results at 60 Weeks
D P Kotler*1, C Grunfeld2, N Muurahainen3, C Wanke4, M Thompson5, D Bock3, J Gertner3, and Serostim in the Treatment of Adipose Redistribution Syndrome (STARS) Trial Investigator Group
1Columbia Univ. and St. Lukes Hosp. Ctr., New York, NY, USA; 2Univ. of California, San Francisco, VA Med. Ctr., USA; 3Serono, Inc., Rockland, MA, USA; 4Tufts Univ. Sch. of Med., Boston, MA, USA; and 5AIDS Res. Consortium of Atlanta, GA, USA
12:15 pm       81Incidence of Non-AIDS-defining Malignancies in the HIV Outpatient Study
P Patel*1, R M Novak2, T Tong1, P Behari2, A Moorman1, F J Palella Jr2, S D Holmberg1, and HIV Outpatient Study (HOPS)
1Atlanta, GA, USA and 2Chicago, IL, USA
12:30 pm       82Surgical Outcomes of HIV+ Patients in the Era of HAART
M Horberg*1, L Hurley2, D Klein3, S Follansbee4, J Flamm5, and G Green6
1Kaiser-Santa Clara, CA, USA; 2Kaiser Permanente, Oakland, CA, USA; 3Kaiser Permanente, Hayward, CA, USA; 4Kaiser-San Francisco, CA, USA; 5Kaiser-Sacramento, CA, USA; and 6Kaiser-Santa Rosa, CA, USA