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Session 26
Oral Abstracts Retroviral Pathogenesis Wednesday, 10 am - 12:30 pm Room 2005 |
| Moderators | Malcolm Martin NIAID, NIH, DHHS, Bethesda, MD, USA Cheryl Stoddart Gladstone Inst of Virology and Immunology, Univ of California, San Francisco, USA |
| 10:00 am 121 | Mutations in p6 Gag Associated with Alterations in Replication Capacity in Drug Sensitive HIV-1 Are Implicated in the Budding Process Mediated by TSG101 and AIP1 M Bates*, C Chappey, and N Parkin ViroLogic Inc., South San Francisco, CA, USA |
| 10:15 am 122 | Identification of a Gene Product, Murr1, that Restricts HIV-1 Replication in Primary Resting CD4+ T-lymphocytes L Ganesh*1, E Burstein1, A Guha-Niyogi1, M K Louder1, J R Mascola1, L W J Klomp2, C Wijmenga2, C S Duckett3, and G Nabel1 1Vaccine Res. Ctr., NIAID, NIH, DHHS, Bethesda, MD, USA; 2Univ. Med. Ctr. Utrecht, Netherlands; and 3Univ. of Michigan, Ann Arbor, USA |
| 10:30 am 123LB | De Novo Latent Infection of Quiescent CD4+ T Cells in the Absence of Exogenous Stimuli U O'Doherty*, C Baytop, J Yu, and W Swiggard Univ. of Pennsylvania, Philadelphia, USA |
| 10:45 am 124LB | HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T Cells K Oswald-Richter, S M. Grill, N Shariat, M Leelawong, M S Sundrud, and D Unutmaz* Vanderbilt Univ. Med. Sch., Nashville, TN, USA |
| 11:00 am 125 | Sequence Determinants in the gp120 V1-V4 Region Modulate Susceptibility to Neutralization by Autologous and Pooled Plasma C Derdeyn*1, J Decker2, F Bibollet-Ruche1, J Mokili3, M Muldoon4, M Heil1, F Kasolo5, R Musonda6, S Allen1, B H Hahn1, G Shaw2, B T Korber3, and E Hunter1 1Univ. of Alabama at Birmingham, USA; 2Howard Hughes Med. Inst., Birmingham, AL, USA; 3Los Alamos Natl. Lab., Los Alamos, NM, USA; 4Univ. of Manchester Inst. of Sci. and Technology, UK; 5Univ. Teaching Hosp., Lusaka, Zambia; and 6Tropical Disease Res. Ctr., Ndola, Zambia |
| 11:15 am 126 | Decreased Survival of B Cells of HIV-Viremic Patients Mediated by Altered Expression of Receptors of the TNF Superfamily S Moir*1, A Malaspina1, E Donoghue1, J Vasquez1, T-W Chun1, M Planta1, O Pickeral2, C Birse2, and A S Fauci1 1NIAID, NIH, DHHS, Bethesda, MD, USA and 2Human Genome Sci. Inc., MD, USA |
| 11:30 am 127 | Mechanism(s) Responsible for the Immunodeficiency Induced by Highly Pathogenic SHIV and SIV Appear to Be Fundamentally Different T Igarashi*1, Y Endo1, Y Nishimura1, C Buckler1, R Sadjadpour1, O Donau1, M J Dumaurier2, R Plishka1, A Buckler-White1, and M Martin1 1NIAID, NIH, DHHS, Bethesda, MD, USA and 2Weill Med. Coll. of Cornell Univ., New York, NY, USA |
| 11:45 am 128 | Frequent Simian Retrovirus Infection in Persons Occupationally Exposed to Nonhuman Primates W M Switzer1, V Shanmugam1, V Bhullar1, J Yee2, N Lerche2, B Parekh1, M Cong1, R Boneva1, L E Chapman1, T M Folks1, and W Heneine*1 1CDC, Atlanta, GA, USA and 2Univ. of California, Davis, USA |
| 12:00 pm 129 | Modeling T-cell Labeling with BrdU in SIV-infected Sooty Mangabeys R M Ribeiro*1, M Di Mascio2, H M McClure3, R P Johnson4, A Kaur4, and A S Perelson5 1Univ. of Oxford, UK; 2NIAID, NIH, DHHS, Bethesda, MD, USA; 3Yerkes Natl. Primate Res. Ctr., Atlanta, GA, USA; 4New England Regional Primate Res. Ctr., Harvard Med. Sch., Southborough, MA, USA; and 5Los Alamos Natl. Lab., Los Alamos, NM |
| 12:15 pm 130 | Th1-type SIV-specific Cellular Immune Responses Targeting Structural Proteins Are Consistently Detected in Naturally SIV-infected Sooty Mangabeys Z C Wang*1, H M McClure2, and A Kaur1 1New England Regional Primate Res. Ctr., Harvard Med. Sch., Southborough, MA, USA and 2Yerkes Natl. Primate Res. Ctr., Emory Univ., Atlanta, GA, USA |