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Session 55   Poster Abstracts
Virus Replication: Uncoating, RT, and Integration
Monday, 1:30 - 3:30 pm
Poster Hall
324
Role of HIV-1 Matrix Phosphorylation in an Early Post-entry Step of Virus Replication
R Kaushik*, and L Ratner
Washington Univ. Sch. of Med., St Louis, MO, USA
325The MA Protein as a Regulator of HIV-1 Core Stability
M R Davis*, and C Aiken
Vanderbilt Univ. Sch. of Med., Nashville, TN, USA
326The Dimer Interface of the HIV Protease Is a Key Specificity Determinant of GagPol Processing
A H Kaplan*, L Everitt, S Choudhury, and S C Pettit
Univ. of North Carolina at Chapel Hill, USA
327
Structural Variability of the Initiation Complex of HIV-1 Reverse Transcription
V Goldschmidt1, J-C Paillart1, M Rigourd1, C Beyer2, A-M Aubertin2, B Ehresmann1, C Ehresmann1, and R Marquet*1
1CNRS, Strasbourg, France and 2INSERM, Strasbourg, France
328The Infectivity Enhancement of HIV-1 Nef Involves the Actin Cytoskeleton
E M Campbell*, and T J Hope
Univ. of Illinois at Chicago, USA
329Evidence that Cell Cycle Arrest in G2 Can Promote the Early Steps of HIV Infection
B Groschel*, and F D Bushman
Salk Inst. for Biological Studies, La Jolla, CA, USA
330The Carboxyl Terminus of HIV-1 Integrase Facilitates Viral Nuclear Import
T Cunningham, D Kaufman, M Topper*, M Muesing, and Y Luo
Aaron Diamond AIDS Res. Ctr., Rockefeller Univ., New York, NY, USA
331Kinetics of the 3' Processing Reaction of HIV-1 Integrase as Determined by Fluorescence Cross Correlation Spectroscopy
J Vercammen*1, M Witvrouw2, E De Clercq2, Z Debyser2, and Y Engelborghs1
1Lab. for Biomolecular Dynamics, Katholieke Univ. Leuven, Belgium and 2Rega Inst. for Med. Res., Katholieke Univ. Leuven, Belgium and The European TRIoH Consortium
332The Relationship Between Retroviral Integration and Host Cell Transcription
L Maxfield*, N Bell, C Fraize, and J Coffin
Tufts Univ., Boston, MA, USA
333Targeting of Lentiviral and Retroviral Integration
R Mitchell*1, B Beitzel1, A Schroder2, P Shinn1, H Chen1, C Berry3, J Ecker1, and F Bushman1
1Salk Inst. for Biological Studies, La Jolla, CA, USA; 2GenProbe, San Diego, CA, USA; and 3Univ. of California, San Diego, Sch. of Med., USA
334Mutation of alpha-Helix 6 of the HIV-1 IN Central Domain Causes Loss of DNA Synthesis and Disrupts the Quaternary Structure of Integrase
M Padow*, and J Kappes
Univ. of Alabama at Birmingham, USA
335
Integration Sites of HTLV-I Provirus in Adult T-cell Leukemia Cells
K Doi, E-I Kodama, Y Satou, J-I Yasunaga, Y Taniguchi, and M Matsuoka*
Inst. for Virus Res., Kyoto Univ., Japan
336
Structure of the 5'-Untranslated Region of HIV-1 Genomic RNA in Infected Cells and in Viral Particles
J-C Paillart*1, M Dettenhofer2, X-F Yu2, B Ehresmann1, C Ehresmann1, and R Marquet1
1CNRS, Strasbourg, France and 2Johns Hopkins Sch. of Hygiene and Publ. Hlth., Baltimore, MD, USA
337Communication between the Spatially Separate Active Site and Dimer Interface of KSHV Protease Revealed by Small Molecule Inhibition
A Marnett*, A Nomura, N Shimba, S Mahrus, P Ortiz de Montellano, and C Craik
Univ. of California, San Francisco, USA
337bLEDGF/p75 Determines Cellular Trafficking of Diverse Lentiviral but not Murine Oncoretroviral Integrase Proteins and Is a Component of Functional Lentiviral Pre-integration Complexes
E Poeschla*, M Llano, M Vanegas, O Fregoso, D Saenz, S Chung, and M Peretz
Mayo Clin. Coll. of Med., Rochester, MN, USA