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Session 64   Poster Abstracts Viral Tropism and Coreceptor Use Tuesday, 1:30 - 3:30 pm Poster Hall

409	Intrinsic Obstacles to HIV Co-receptor Switching D E Mosier*, C Pastore, A Ramos, and D Geerdes Scripps Res. Inst., La Jolla, CA, USA
410	Tissue-derived SHIV from Late Stage Animals Are Macrophage Tropic and Use CXCR4 for Infections of both Rhesus Macaque PBMC and Alveolar Macrophage H Imamichi*1, O K Donau2, T Igarashi2, M-J Dumaurier3, R Sadjadpour2, R J Plishka2, A Buckler-White2, C Buckler2, A F Suffredini4, H C Lane2, J P Moore3, and M A Martin2 1SAIC-Frederick, Inc., MD, USA; 2NIAID, NIH, DHHS, Bethesda, MD, USA; 3Cornell Univ., New York, NY, USA; and 4Clin. Ctr., NIH, Bethesda, MD, USA
411	Macrophage Tropism of SIVsm Is Maintained in Progressive Disease, but Decreases in Infected Macaques that Do Not Progress to Disease A Nordqvist*1, H Fredlund2, D Vödrös1, R Thorstensson2, and E-M Fenyö1 1Lund Univ., Sweden and 2Swedish Inst. for Infectious Disease Control, Stockholm, Sweden
412	Molecular Determinants for Decreasing Sensitivity to Coreceptor Antagonists of Evolving R5 and X4 Virus Variants in Natural Course of Infection H Schuitemaker*, F Koning, E Stalmeijer, M Navis, J Dekker, B Boeser-Nunnink, and R van Rij Sanquin Res. and Univ. of Amsterdam, The Netherlands
413	CD4 Signaling in Primary Human Macrophages is Through the ERK-1/2 MAP Kinase Pathway B Tomkowicz*, C-H Lee, Y Yi, and R G Collman Univ. of Pennsylvania, Philadelphia, USA
414	HIV-1-mediated Apoptosis Occurs in Macrophages Infected by X4, but Not by R5 Viruses S Aquaro*1, A Ranazzi1, M Bellocchi1, T Guenci1, P Saccomandi1, S Giannella1, D Schols2, E Garaci1, R Caliò1, and C F Perno1 1Univ. of Rome Tor Vergata, Italy and 2Rega Inst. for Med. Res., Leuven, Belgium
415	Genotypic Potential for Syncytium Induction Characterizes Early V3 Loop Evolution in Singly and Dually-infected Individuals with Rapid HIV Disease Progression M A Jensen*1, G S Gottlieb1, A B van 't Wout1, K G Wong1, J B Margolick2, and J I Mullins1 1Univ. of Washington, Seattle, USA and 2Johns Hopkins Sch. of Hygiene and Publ. Hlth., Baltimore, MD, USA