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Session 65
Poster Abstracts Viral Targets and Reservoirs Tuesday, 1:30 - 3:30 pm Poster Hall |
| 416 | Characterization of DC-SIGN and DC-SIGNR Transcript Isoforms in Human Vaginal and Rectal Mucosa H Liu*1, F Hladik2, T Andrus1, P Nelson2, P Sakchalathorn2, G Lentz1, L Corey1,2, M J McElrath1,2, and T Zhu1 1Univ. of Washington Sch. of Med., Seattle, USA and 2Fred Hutchinson Cancer Res. Ctr., Seattle, WA, USA |
| 417 | Lack of SIV Target Cells in African Non-human Primate: Host or Virus Adaptation? I Pandrea*, C Apetrei, J Dufour, M Mefford, R Bohm, P Marx, A Lackner, and R Veazey Tulane Natl. Primate Res. Ctr., Covington, LA, USA |
| 418 | Differences in Dendritic Cell Populations and Signaling May Account for Divergent SIV Infection Outcomes in Rhesus Macaques and Sooty Mangabeys A P Barry*, R Chavan, M Wernett, M McCausland, S Staprans, G Silvestri, and M B Feinberg Emory Univ., Atlanta, GA, USA |
| 419 | Parallel Rather Than Sequential Targeting of Intraepithelial Langerhans and T Cells during Vaginal HIV-1 Transmission F Hladik*1, P Sakchalathorn1, L Ballweber1, G Lentz2, D Eschenbach2, and M J McElrath1 1Fred Hutchinson Cancer Res. Ctr., Seattle, WA, USA and 2Univ. of Washington, Seattle, USA |
| 420 | The Distal Lower Genitourinary Tract as a Source of Seminal HIV R Coombs*, L Deutsch, S Ross, J Dragavon, S Harb, A Motoshige, L Stensland, K Diem, M Hooton, A Collier, and J Krieger Univ. of Washington, Seattle, USA |
| 421 | HIV-1 Cervicovaginal Reservoirs in the Era of HAART G Nunnari*1, J Kulkosky1, J Sullivan1, Y Xu1, W Cavert2, P Nyirjesy1, I Frank3, and R J Pomerantz1 1Ctr. for Human Virology and Biodefense, Thomas Jefferson Univ., Philadelphia, PA, USA; 2Univ. of Minnesota, Minneapolis, USA; and 3Univ. of Pennsylvania, Philadelphia, USA |
| 422 | The Presence of Extracellular Virion-associated HIV-RNA in Lymphoid Tissue Reflects Local Productive Infection: A Detailed Analysis of Lymphatic HIV Transcription Patterns in vivo M Fischer*1, B Joos1, J K Wong2, B Hirschel3, M Opravil1, R Weber1, H F Guenthard1, and The Swiss HIV Cohort Study 1Univ. Hosp. Zurich, Switzerland; 2Univ. of California, San Diego and VA Med. Ctr., La Jolla, CA, USA; and 3Univ. Hosp. Geneva, Switzerland |
| 423 | Expression of Latent HAART-persistent HIV-1 Induced by Novel Cellular Activating Agents: Molecularly Interrogating HIV-1 Reservoirs R Pomerantz*1, J Sullivan1, Y Xu1, E Souder1, D Hamer2, and J Kulkosky1 1Thomas Jefferson Univ., Philadelphia, PA, USA and 2NCI, NIH, DHHS, Bethesda, MD, USA |
| 424 | Purging HIV-1 Viral Reservoirs: The Role of IL-7 F X Wang*1, Y Xu1, J Sullivan 1, J Fisher1, E Souder1, E Acheampong1, E Argyris1, I Frank2, J Kulkosky1, R J Pomerantz1, and G Nunnari1 1Ctr. for Human Virology and Biodefense, Thomas Jefferson Univ., Philadelphia, PA, USA and 2Univ. of Pennsylvania, Philadelphia, USA |
| 425 | Actinomycin D and IL-6 Synergistically Stimulate HIV-1 Replication in a Latently Infected Cell Line U1 through Activating MRP8 Y Liu*1, R A Lempicki1, H C Lane2, and T Imamichi1 1SAIC-Frederick, Inc., MD, USA and 2NIAID, NIH, DHHS, Bethesda, MD, USA |
| 426 | CD14lo/CD16hi Monocytes are More Permissive to HIV-1 Infection in vitro and May Selectively Harbour HIV-1 in Patients on HAART P Ellery1,2, C Sonza1, G Paukovics1, P U Cameron3, A Solomom2,4, SR Lewin2,4, S M Crowe*1,2,4,5, and 1Macfarlane Burnet Inst. for Med. Res. and Publ. Hlth., Melbourne, Australia; 2Monash Univ., Melbourne, Australia; 3Univ. of Melbourne, Australia; 4Alfred Hosp., Melbourne, Australia; and 5Natl. Ctr. for HIV Virology Res., Melbourne, Australia |
| 427 | Quantitation of Rare HIV-1 Integration Events in PBMC from HIV-1-infected Individuals Using Repetitive Sampling Techniques J Yu1, W J Swiggard1, T Theodosopoulos2, and U O'Doherty*1 1Univ. of Pennsylvania, Philadelphia, USA and 2Drexel Univ., Philadelphia, PA, USA |
| 427b | An Anti-CD45RO Immunotoxin Kills Latently Infected, Replication-competent, CD4+ T Cells Purified from HIV+ Individuals on HAART with Viremia below the Limit of Detection J Saavedra-Lozano*1, Y Cao1, J Callison1, R Sarodi1, D Peterson1, L Picker2, O Ramilo1, and E Vitetta1 1Univ. of Texas Southwestern Med. Ctr., Dallas, USA and 2Oregon Hlth. and Sci. Univ., Portland, USA |
| 427c | Coaxing HIV-1 from Resting CD4+ T Cells: Valproic Acid Induces Latent Viral Expression D M Margolis*1,2, G Lehrman1, N M Archin1, L Ylisastigui1, M B Kvanli2, D Turner2, J Wagner2, H Wise2, and R J Bosch3 1Univ. of Texas Southwestern Med. Ctr., Dallas, USA; 2North Texas Veterans Hlth. Care Systems, Dallas, USA; and 3Harvard Sch. of Publ. Hlth., Boston, MA, USA |
