Session: Neuropathogenesis: Viral Co-Factors

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Session 71 Poster Abstracts
Neuropathogenesis: Viral Co-Factors
Wednesday, 1:30 - 3:30 pm
Poster Hall


459	*Comparison of HIV-1 pol* and env Sequences of Blood, CSF, Brain, and Spleen Isolates, a Longitudinal Study** E-C Caragounis, B Svennerholm, C Nordborg, S Westergren, M Lindh, L Hagberg, and M Gisslén Göteborg Univ., Sweden*
460	Phenotype Analysis of HIV-1 Envelopes Amplified from Brain and Lymph Node Tissue of AIDS Patients with Neuropathology Identifies Envelopes with an Enhanced Tropism and Fusigenicity for Macrophages P Peters*¹, J Bhattacharya¹, S Hibbitts², M Dittmar³, G Simmons⁴, J Bell⁵, P Simmonds⁶, and P Clapham¹ ¹Univ. of Massachusetts Med. Sch., Worcester, USA; ²Univ. of Wales Coll. of Med., Cardiff, UK; ³Hygiene-Inst, Heidelberg, Germany; ⁴Univ. of Pennsylvania, Philadelphia, USA; ⁵Western Gen. Hosp., Edinburgh, Scotland; and ⁶Univ. of Edinburgh, Scotland
461	HIV-1 Nef Sequence Diversity Is Associated with Reduced Neural Stem Cell Survival G van Marle¹, J McArthur², S Rourke³, and C Power¹ ¹Univ. of Calgary, Alberta, Canada; ²Johns Hopkins Univ., Baltimore, MD, USA; and ³Univ. of Toronto, Ontario, Canada*
462	Role of HIV-1 Vpr-binding Brain Protein (VBP) in Neuropathogenesis of HIV-1-associated Dementia M Miles, M Janket, B Majumder, E Schafer, C Achim, and V Ayyavoo Univ. of Pittsburgh, PA, USA*
463	Nociceptive Neruons Are Particularly Vulnerable to gp120 Neurotoxicity S Keswani, M Polley, and A Hoke Johns Hopkins Hosp., Baltimore, MD, USA*
464	Induction of Neuron Death by HIV-1 Tat Expression in Astrocytes B Zhou, and J He Indiana Univ. Sch. of Med., Walther Cancer Inst., Indianapolis, USA*
465	Peripheral Nerve-derived HIV-1 is Both CXCR4 and CCR5 Dependent and Reduces Neurite Outgrowth in Dorsal Root Ganglia Cultures G Jones¹, Y Zhu¹, J C McArthur², C Pardo², C Silva¹, O Keppler³, and C Power¹ ¹Univ. of Calgary, Alberta, Canada; ²Johns Hopkins Univ., Baltimore, MD, USA; and ³Univ. of Heidelberg, Germany*
466	HIV-1 Gag Host Cell Interactions During Budding and Assembly in Macrophages/Microglia R Vos, A Albright, E Ryzhova, and F Gonzalez-Scarano Univ. of Pennsylvania, Philadelphia, USA*
467	Antiviral Effect of HIV-1-specific siRNA against Targets Conserved in Select Neurotropic Strain R Dave, and R Pomerantz Ctr. for Human Virology and Biodefense, Thomas Jefferson Univ., Philadelphia, PA, USA*
468	Sustained Antiretroviral Activity of Indinavir Nanosuspensions in Primary Monocyte-derived Macrophages J Limoges¹, I Kadiu¹, D Morin¹, M Chaubal², J Werling², B Rabinow², and H E Gendelman¹ ¹Univ. of Nebraska Med. Ctr., Omaha, USA and ²Baxter Healthcare Corp., Round Lake, IL, USA*
469	HIV, Hepatitis C, and Methamphetamine Dependence Independently Worsen Neuropsychological Performance S Letendre, M Cherner, J Marquie-Beck, R Ellis, R Heaton, T Marcotte, K Harrington, B Gragg, J McCutchan, I Grant, and The HNRC Group Univ. of California, San Diego, USA*