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Session 79   Poster Abstracts
New Antiretroviral Agents: Novel Approaches
Wednesday, 1:30 - 3:30 pm
Poster Hall
542Selective Ablation of HIV-infected Lymphocytes by Inhibitors of Hypusine Formation: The Mature Eukaryotic Translation Initiation Factor 5A Is Pivotal for Retroviral Suppression of Apoptosis
H M Hanauske-Abel*1, P Palumbo1, M H Park2, E C Wolff2, A Fernadez1, Z Garcia1, N Hardegen2, A M Popowicz3, B M Cracchiolo1, and G L McLendon4
1New Jersey Med. Sch.-UMDNJ, Newark, USA; 2NIH, DHHS, Bethesda, MD, USA; 3Rockefeller Univ., New York, NY, USA; 4Princeton Univ., NJ, USA; and 5Hamburg Univ., Germany
543Anti-HIV Effects of Chloroquine: Inhibition of Viral Particle Glycosylation and Synergism with Protease Inhibitors
A Savarino*1, M B Lucia1, E Rastrelli1, S Rutella1, C Golotta1, E Morra2, E Tamburrini1, J R Boelaert3, K Sperber4, and R Cauda1
1Catholic Univ. of S. Cuore, Rome, Italy; 2Univ. of Turin, Italy; 3AZ Sint-Jan, Brugge, Belgium; and 4Mount Sinai Sch. of Med., New York, NY, USA
544Antiviral Effects of Mifepristone and its Analogs on HIV-1 Vpr-Induced Virus Replication
E Schafer*, M Wagner, and V Ayyavoo
Univ. of Pittsburgh, PA, USA
545Determinants of Activity, in vitro Metabolism and in vivo Disposition of the Novel Maturation Inhibitor PA-457
D E Martin*1, P Smith2,3, R Goila-Gaur1,2, K Salzwedel1, F Li1, N Kilgore1, M Reddick1, C Matallana1, A Castillo1, D Zoumplis1, G Allaway1,2, E Freed1,2, and C Wild1
1Panacos Pharm., Gaithersburg, MD, USA; 2NCI, NIH, DHHS, Frederick, MD, USA; and 3Univ. of North Carolina at Chapel Hill, USA
546
Selective Killing of HIV Infected Cells by Small Molecule Cyclin Dependent Kinase Inhibitors
J Hesselgesser*, C S Gibbs, and R Shibata
Gilead Sci., Inc., Foster City, CA, USA