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Session 90   Poster Abstracts Evolution of Drug Resistance Wednesday, 1:30 - 3:30 pm Poster Hall

642	Giant Effect of Recombination on Accumulation Rate of Linked Advantageous Mutations I M Rouzine*, and J M Coffin Tufts Univ., Boston, MA, USA
643	High Conservation of the HIV-1 Reverse Transcriptase under Drug Pressure F Ceccherini-Silberstein*1, M Santoro1, V Svicher1, C Gori2, F Gago3, M Ciccozzi4, M Ruiz Alvarez4, R D'Arrigo2, A Bertoli1, S Giannella2, A Cenci2, M P Trotta2, A d'Arminio Monforte5, A Antinori2, and C F Perno1,2 1Univ. of Rome, Tor Vergata, Italy; 2INMI "L. Spallanzani" of Rome, Italy; 3Univ. of Alcala, Madrid, Spain; 4Inst. Superiore di Sanita, Rome, Italy; and 5Univ. of Milan, Italy
644	Natural Polymorphisms in HIV-1 Protease, Reverse Transcriptase, and Integrase are Maintained by Selection S L Kosakovsky Pond*1, D D Richman1,2, J A McCutchan1, A J Leigh Brown3, and S D W Frost1 1Univ. of California, San Diego, USA; 2VA San Diego Healthcare System, La Jolla, CA, USA; and 3Univ. of Edinburgh, Scotland
645	Competing Occurrence and Mutation Pathways of Nucleoside Reverse Transcriptase Inhibitor Associated Mutations P Flandre*1, N T Parkin2, C Petropoulos2, and C Chappey2 1INSERM U472, Villejuif, France and 2ViroLogic Inc., South San Francisco, CA, USA
646	Differential Evolution of Drug Resistance Mutations and Presence of M Tropism in Vaginal HIV-1 Despite Advanced HIV-1 Disease G l Tirado*, G R Jove, and Y Yamamura Ponce Sch. of Med., PR, USA
647	Persistent Viral Infection and Sequence Evolution in Semen and Blood Compartments in HIV-infected Patients following Long-term Potent Antiretroviral Therapy J K Craigo*1, B Patterson2, S Paranjpe1, K Kulka1, M Ding1, R C Montelaro1, J Mellors1, and P Gupta1 1Univ. of Pittsburgh, PA, USA and 2Northwestern Univ., Evanston, IL, USA
648	Different Evolution of Genotypic Patterns in Patients Failing HAART with Discordant Immunologic Response B C Ciancio, I Uccella, S Bonfigli, F Ceccherini Silberstein, G D'Offizi, F Forbici, M Zaccarelli, U Visco-Comandini, R D'Arrigo, E Boumis, C Gori, V Tozzi, P Narciso, C F Perno, and A Antinori* INMI Lazzaro Spallanzani, IRCCS, Rome, Italy
649	Lowering Drug Pressure to Stabilize Multidrug Resistant HIV Evolution and Pathogenicity (Vista ANRS 109) O Launay1, X Duval2, C Dalban3, D Descamps2, G Peytavin2, A Certain2, S Mouajjah3, D Costagliola3, and F Clavel*4 1Hosp. Cochin, Paris, France; 2Hosp. Bichat-Claude Bernard, Paris, France; 3Inserm E0214, Paris, France; and 4Inserm U552, Paris, France
650	Genotypic Analysis of HIV-1 Drug Resistance at the Limits of Detection: Virus Production without Evolution in Treated Adults with <50 Copies/mL of Plasma HIV-1 RNA T Kieffer*1, M Finucane1, R Nettles1, T Quinn1,2, K Broman3, S Ray1, D Persaud1, and R Siliciano1,4 1Johns Hopkins Univ. Sch. of Med., Baltimore, MD, USA; 2NIAID, NIH, DHHS, Bethesda, MD, USA; 3Johns Hopkins Univ. Sch. of Publ. Hlth., Baltimore, MD, USA; and 4Howard Hughes Med. Inst., Baltimore, MD, USA
651	Frequency, Magnitude, Duration, and Genotypic Characterization of Intermittent Viremia ("blips") in Patients with Sustained Suppression of Plasma HIV-1 RNA T Kieffer*1, R Nettles1, T Quinn1,2, B Jackson1, J Cofrancesco1, J Gallant1, D Persaud1, and R Siliciano1,3 1Johns Hopkins Univ. Sch. of Med., Baltimore, MD, USA; 2NIAID, NIH, DHHS, Bethesda, MD, USA; and 3Howard Hughes Med. Inst., Baltimore, MD, USA