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Session 98
Poster Abstracts Drug Resistance Testing: New Methods, Interpretations, and Reproducibility Monday, 1:30 - 3:30 pm Poster Hall |
| 695 | Single-genome Sequencing Is More Sensitive than Standard Genotype Analysis for Detection of HIV-1 Drug-resistance Mutations M Kearney*1, S Palmer1, F Maldarelli1, C Bixby2, H Bazmi2, D Rock3, J Falloon4, R Davey4, R Dewar3, J Metcalf3, J Mellors2, and J Coffin1 1HIV Drug Resistance Prgm., NCI, NIH, DHHS, Frederick, MD, USA; 2Univ. of Pittsburgh, PA, USA; 3NIAID/CCMD Clin., NIH, DHHS, Bethesda, MD, USA; and 4Lab. of Immunoregulation, NIAID, NIH, DHHS, Bethesda, MD, USA |
| 696 | A Novel Single-cell Level Phenotypic Assay for Residual Drug Susceptibility and Reduced Replication Capacity of Drug-resistant HIV-1 H Zhang*1, Y Zhou1, C Alcock1, T Kiefer1, D Monie1, J Siliciano1, Q Li2, P Pham1, J Cofrancesco1, D Persaud1, and R Siliciano1,3 1Johns Hopkins Univ. Sch. of Med., Baltimore, MD, USA; 2Univ. of Maryland Sch. of Pharmacy, Baltimore, USA; and 3Howard Hughes Med. Inst., Baltimore, MD, USA |
| 697 | Accuracy of Neural Network Models in Predicting HIV Treatment Response from Genotype May Depend More on Diversity than Size of Data Sets B Larder*1, D Wang1, A Revell2, R Harrigan3, J Montaner3, and C Lane4 1The HIV Resistance Response Database Initiative (RDI), Cambridge, UK; 2RDI Ltd., London, UK; 3British Columbia Ctr. for Excellence in HIV/AIDS Vancouver, Canada; and 4NIAID, NIH, DHHS, Bethesda, MD, USA |
| 698 | Predicting HIV Drug Resistance Using Supervised Machine Learning Methods J Ravela*, A Ben-Hur, and R W Shafer Stanford Univ., CA, USA |
| 699 | Performance of the Celera Diagnostics ViroSeq HIV-1 Genotyping System v2.0 for Sequence-based Analysis of Diverse HIV-1 Strains S H Eshleman*1, J Hackett Jr2, S P Cunningham1, B Drews3, P Swanson2, C Brennan2, S G Devare2, L Zekeng4, L Kaptue5, and N Marlowe3 1Johns Hopkins Med. Inst., Baltimore, MD, USA; 2Abbott Labs., Abbott Park, IL, USA; 3Celera Diagnostics, Alameda, CA, USA; 4Lab. de Santé Hygiène Mobile, Yaoundé, Cameroon; and 5Univ. of Yaoundé, Cameroon |
| 700 | A Multi-center Evaluation of Intra-laboratory Reproducibility of HIV-1 Genotyping D Brambilla*1, D Huang2, S Granger1, C Jennings2, and J Bremer2 1New England Res. Inst., Watertown, MA, USA and 2Rush Univ. Med. Coll., Chicago, IL, USA |
