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Session 11  Poster Discussion
Poster Discussion: NK Cells in HIV Infection
Wednesday, 2:30 - 3:30 pm
311

Discussants:
  Yves Levy
  Henri Mondor Hosp, Créteil, France

  Antonio Valentin
  NCI-Frederick, NIH, DHHS, MD, USA
      414 Innate Immunity in HIV Infection: Enhanced Natural Killer Cell-death and Turnover Mediated by Altered Expression of Interferon-stimulated Genes (ISG)s
Shyam Kottilil*1, J Jackson1, T W Chun1, M O'Shea1, M McLaughlin1, J Yang2, R Lempicki2, and A Fauci1
1NIAID, Bethesda, MD, USA and 2SAIC-NCI, Frederick, MD, USA
      415 Investigation of Natural Killer Cell Function and Phenotype in HIV Long-term Non-progression
Geraldine O'Connor*1, A Holmes2, F Mulcahy2, and C Gardiner1
1Trinity Coll Dublin, Ireland and 2St James's Hosp, Dublin, Ireland
      416 Chronic HIV-1 Infection Leads to a Loss of NK Cells with a Preferential Depletion of CD56bright NK Cells
Galit Alter*, J Malenfant, N Teigen, and M Altfeld
Massachusetts Gen Hosp, Boston, USA
      417 Low NK Cell Numbers are Associated with Fast Progressive HIV-infection
B Castro Frenzel1, H Heiken1, U Moebius1, S Kovalczik1, S Corey2, K Ulbricht1, M Stoll1, R Schmidt1, S Kalams2, and Dirk Meyer-Olson*1
1Med Univ Hannover, Germany and 2Vanderbilt Univ Med Ctr, Nashville, TN, USA
      418 Disconnect between the Recovery of NK Cell-mediated Cytotoxicity to HIV-infected Targets and Restoration of NK Subsets in ART-suppressed HIV-1-infected Individuals
Livio Azzoni*1, J Chehimi1, M Farabaugh1, S Creer1, K Mounzer2, J Kostman3, C Gallo2, J Ondercin2, J Schull2, and L Montaner1
1Wistar Inst, Philadelphia, PA, USA; 2Jonathan Lax Clin, Philadelphia FIGHT, PA, USA; and 3Univ of Pennsylvania, Philadelphia, USA
      419 Natural Killer Cell NKG2A Expression is Unaffected by Short Term Increases in HIV-1 Viremia during Treatment Interruption
Christopher M Mela*1, M Goodier1, C Burton1, N Imami1, M Nelson2, B Gazzard2, and F Gotch1
1Imperial Coll, London, UK and 2Chelsea and Westminster Hosp, London, UK
      420 Longitudinal Analysis and Modeling Identifies Changes in Innate Immunity Parameters as Predictive Correlates of CD4 Reconstitution in ART-Treated HIV-1 Infection
Livio Azzoni*1, J Chehimi1, R June1, M Farabaugh1, B Thiel1, L Zhou2, and L Montaner1
1Wistar Inst, Philadelphia, PA, USA and 2Univ of Pennsylvania, Philadelphia, USA
      421 Retained NK and DC Subsets upon Viral Replication following Treatment Interruption in Chronically Suppressed HIV-1-infected Subjects
Emmanouil Papasavvas*1, L Azzoni1, J Chehimi1, B Thiel1, M Pistilli1, M Farabaugh1, A Mackiewicz1, S Creer1, C Gallo2, K Mounzer2, J Ondercin2, J Shull2, J Kostman3, and L Montaner1
1Wistar Inst, Philadelphia, PA, USA; 2Philadelphia FIGHT, PA, USA; and 3Philadelphia FIGHT, PA, USA
      422 Altered NK Cell Repertoire Is Detected by Real-time PCR and Phenotypic Analysis of Exposed Uninfected Vietnamese Intravascular Drug Users
S Ravet1, D Scott-Algara2, E Bonnet1, H Trang3, L Troung3, N Nguyen4, E Vivier5, F Barré-Sinoussi2, G Pancino2, and Pascale Paul*1
1Conception Hosp, Marseille, France; 2Pasteur Inst, Paris, France; 3Inst Pasteur, Ho Chi Minh City, Vietnam; 4Hosp Binh Trieu, Ho Chi Minh City, Vietnam; and 5Inst Natl Hlth and Res Med, Marseille, France