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Session 21  Oral Abstracts
Pregnancy and Prevention of Perinatal HIV Transmission
Thursday, 10 am - 12:30 pm
302-304

Moderators:
  Robert Maupin
  Louisiana State Univ Hlth Sci Ctr, New Orleans, USA

  Elaine Abrams
  Harlem Hosp, Columbia Univ, New York, NY, USA
10:00 am         67 HAART in Pregnancy: Safety, Effectiveness, and Protection from Viral Resistance: Results from the DREAM Cohort
Leonardo Palombi*1, P Germano2, G Liotta1, C Perno1, P Narciso3, A da Cruz Gomes4, M Valls Blazquez5, S Loureiro5, S Ceffa6, M Magnano San Lio2, M Bartolo2, G Guidotti7, and M Marazzi8
1Univ of Rome 'Tor Vergata', Italy; 2Community of Sant'Egidio, Rome, Italy; 3INMI, DREAM Prgm, Rome, Italy; 4DREAM Prgm, Beira, Mozambique; 5DREAM Prgm, Maputo, Mozambique; 6Community of Sant'Egidio, Novara, Italy; 7DREAM Prgm, Natl Inst of Hlth, Rome, Italy; and 8Drug Resource Enhancement against AIDS and Malnutrition Prgm, LUMSA Univ, Rome, Italy
10:15 am         68 Gestational Diabetes and ART in Pregnant HIV-1-infected women
Maria Isabel Gonzalez-Tome*1, J Ramos1, I Solis1, E Muñoz1, S Guillen1, J Almeda2, I Bates3, P Miralles4, J Peña3, P del Barrio5, C Garaulet6, A Gonzalez-Espinola7, S Oñate8, N Salcedo9, P Segovia4, and For the Spanish Cohort of HIV infected mothers -infants pairs
1Hosp 12 de Octubre, Madrid, Spain; 2Ctr for Epidemiologcal Studies on HIV/AIDS, Barcelona, Spain; 3Hosp La Paz, Madrid, Spain; 4Hosp Gregorio Marañon, Madrid, Spain; 5Hosp de Getafe, Madrid, Spain; 6Hosp de Mostoles, Madrid, Spain; 7Hosp Alcorcón, Madrid, Spain; 8Hosp de Alcalá, Madrid, Spain; and 9Hosp Leganès, Madrid, Spain
10:30 am         69 Mode of Delivery and Postpartum Morbidity among HIV-1-infected Women in Latin America and the Caribbean: The NICHD International Site Development Initiative Perinatal Study
G Duarte1, Jennifer Read*2, R Gonin3, M Losso4, D Chang3, E Cardoso5, R Succi6, L Freimanis3, R de Souza7, M Ceriotto8, and J Korelitz3
1Univ of Sao Paulo Sch of Med, Ribeirao Preto, Brazil; 2NICHD, NIH, DHHS, Bethesda, MD, USA; 3Westat, Rockville, MD, USA; 4Hosp Gen de Agudos Jose Maria Ramos Mejia, Buenos Aires, Argentina; 5Hosp Conceição, Porto Alegre, Brazil; 6Federal Univ of Sao Paulo, Brazil; 7STD/HIV Clin, Caxias do Sul, Brazil; and 8Hosp de Agudos Cecilia Grierson, Buenos Aires, Argentina
10:45 am         70 No Increased Maternal Mortality Attributable to Prolonged Breastfeeding among HIV+ Women in Lusaka, Zambia
Louise Kuhn*1, P Kasonde2, M Sinkala3, C Kankasa2, K Semrau4, G Aldrovandi5, and D Thea4
1Columbia Univ, New York, NY, USA; 2Univ Teaching Hosp, Lusaka, Zambia; 3Lusaka District Hlth Management Team, Zambia; 4Boston Univ, MA, USA; and 5Univ of Southern California, Los Angeles, USA
11:00 am         71 Association of Cord Blood Nevirapine with Self-reported Timing of Dose and HIV-1 Transmission in the HIV NET 012 Study
Brooks Jackson*1, T Parsons1, P Musoke2, C Nakabiito2, D Donnell3, T Fleming4, M Mirochnick5, L Mofenson6, M Fowler7, F MMiro2, L Guay1, and HIVNET 012
1Johns Hopkins Univ, Baltimore, MD, USA; 2Makerere Univ, Kampala, Uganda; 3Fred Hutchinson Cancer Research Center, Seattle, Washington, USA; 4University of Washington, Seattle, Washington, USA; 5Boston University, Boston, MA, USA; 6NICHD, NIH, DHHS, Bethesda, MD, USA; and 7CDC, Atlanta, GA, USA
11:15 am    72LB Addition of 3 Days of ZDV+3TC Postpartum to a Short Course of ZDV+3TC and Single-dose NVP Provides Low Rate of NVP Resistance Mutations and High Efficacy in Preventing Peri-partum HIV-1 Transmission: ANRS DITRAME Plus, Abidjan, Côte d’Ivoire
M L Chaix1, Francois Dabis*2, D Ekouevi2, F Rouet3, B Tonwe-Gold4, I Viho4, L Bequet4, G Peytavin5, H Toure4, H Menan3, V Leroy2, and C Rouzioux1
1Virologie,EA3620, Universite Rene Descartes, CHU Necker, Paris, France; 2INSERM U593, ISPED, Université Victor Segalen, Bordeaux, France; 3CeDReS, CHU de Treichville, Abidjan, Côte d'Ivoire; 4Projet ANRS DITRAME PLUS, Programme PACCI, CHU Treichville, Abidjan, Côte d'Ivoire; and 5Toxicologie, CHU Bichat-Claude Bernard, Paris, France
11:30 am    73LB Nevirapine Resistance and Survival of Women Receiving HAART Subsequent to Prevention of Mother-to-Child Transmission: A Population-based Stochastic Model
Daniel Westreich*, A Van Rie, F Behets, J Eron, and C Van Der Horst
Univ of North Carolina at Chapel Hill, USA
11:45 am    74LB Maternal Single-dose Nevirapine May Not Be Needed to Reduce Mother-to-Child HIV Transmission in the Setting of Maternal and Infant Zidovudine and Infant Single-dose Nevirapine: Results of a Randomized Clinical Trial in Botswana
Roger Shapiro*1, I Thior2, P Gilbert3, S Lockman4, C Wester2, L Smeaton5, L Stevens2, T Ndung'u2, V Novitsky5, E van Widenfelt2, P Mazonde6, T H Lee5, R Marlink5, S Lagakos5, M Essex5, and The Mashi Study Group
1Beth Israel Deaconess Med Ctr, Boston, MA, USA; 2Botswana-Harvard Sch of Publ Hlth AIDS Initiative Partnership, Gaborone; 3Univ of Washington, Seattle, USA; 4Brigham and Women's Hospital, Boston, MA, USA; 5Harvard Sch of Publ Hlth, Boston, MA, USA; and 6Botswana Ministry of Health, Gaborone, Botswana
12:00 pm    75LB Breast-feeding with 6 Months of Infant Zidovudine Prophylaxis vs Formula-feeding for Reducing Postnatal HIV Transmission and Infant Mortality: A Randomized Trial in Southern Africa
Ibou Thior*1, S Lockman2, L Smeaton3, R Shapiro4, C Wester1, J Heymann3, P Gilbert5, L Stevens1, T Peter1, S Kim1, J Makhema1, K McIntosh6, R Marlink3, S Lagakos3, M Essex3, and the Mashi Study Team
1Botswana-Harvard Sch of Publ Hlth AIDS Initiative Partnership, Gaborone; 2Brigham and Women's Hospital, Boston, MA, USA; 3Harvard Sch of Publ Hlth, Boston, MA, USA; 4Beth Israel Deaconess Med Ctr, Boston, MA, USA; 5Univ of Washington, Seattle, USA; and 6Children's Hospital, Boston, MA, USA