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Session 31  Oral Abstracts
Hepatitis Virus Co-Infection
Thursday, 4 - 6 pm
Auditorium
4:00 pm      118 Comparison of Hepatitis C Virus-specific T-cell Responses in Peripheral Blood of Subjects with Chronic HCV Infection with versus without HIV Co-infection When Blocking the Cytokines Involved in Suppressor Activity
Nadia Alatrakchi*1, C S Graham1, K E Sherman2, and M J Koziel1
1Boston, MA, USA and 2Cincinnati, OH, USA
4:15 pm      119 Evidence for a Defect in the HCV-specific CD4+ T-cell Response in HIV/HCV Co-infected Individuals Occurring at Early Stage of HIV Infection
Valerie Dutoit*, D Ciuffreda, J J Gonvers, and G Pantaleo
Univ Hosp, Lausanne, Switzerland
4:30 pm      120 Can Routine Non-invasive Tests Predict Liver Histology in HIV/HCV Co-infection? Analysis of Patients Entering the AIDS PEGASYS Ribavirin International Co-infection Trial (APRICOT)
Richard Sterling*1, E Lissen2, N Clumeck3, R Sola4, M Correa5, J Montaner6, M Sulkowski7, F Torriani8, D Dieterich9, D Thomas7, D Messinger10, and M Nelson11
1Virginia Commonwealth Univ Hlth System, Richmond, USA; 2Virgen del Rocío Univ Hosp, Seville, Spain; 3Ctr Hosp Univ St-Pierre, Brussels, Belgium; 4Hosp del Mar, Univ Autónoma de Barcelona, Spain; 5HCFMUSP, Casa da AIDS, Sao Paulo, Brazil; 6Univ of British Columbia, Vancouver, Canada; 7Johns Hopkins Univ Sch of Med, Baltimore, MD, USA; 8Univ of California, San Diego, Treatment Ctr, USA; 9Mt Sinai Sch of Med, New York, NY, USA; 10IST GmbH, Mannheim, Germany; and 11Chelsea and Westminster Hosp, London, UK
4:45 pm      121 Unexpected Significant Liver Disease among HIV/HCV-coi-nfected Persons with Minimal Fibrosis on Initial Liver Biopsy
Mark Sulkowski*, S Mehta, M Torbenson, R Moore, and D Thomas
Johns Hopkins Univ, Baltimore, MD, USA
5:00 pm      122 Homosexually Transmitted HCV Acute Infection Related to a Clustered Genotype 4 HCV in HIV-1-infected Men and Inefficacy of Early Antiviral Therapy
Marie-Laure Chaix*1, J Serpaggi2, D Batisse3, C Dupont4, A Vallet-Pichard2, H Fontaine2, J P Viard5, C Piketty3, E Rouveix4, C Rouzioux1, L Weiss3, and S Pol2
1Univ Rene Descartes, Ctr Hosp Univ Necker, Paris, France; 2INSERM U370, Ctr Hosp Univ Necker, Paris, France; 3Ctr Hosp Univ Georges Pompidou, Paris, France; 4Ctr Hosp Univ Ambroise Paré, Boulogne, France; and 5Ctr Hosp Univ Necker, Paris, France
5:15 pm      123 Entecavir in HIV/HBV-co-infected Patients: Safety and Efficacy in a Phase II Study (ETV-038)
W Pessoa1, B Gazzard2, A Huang3, C Brandao-Mello4, L Cassetti5, M Correa6, V Soriano7, P Phiri8, A Hall8, E Ledesma8, and R Wilber8
1Inst of Infectologia 'Emilio Ribas', Sao Paulo, Brazil; 2Chelsea and Westminster Hosp, London, UK; 3Univ of Louisville, KY, USA; 4Hosp Gaffrée e Guinle, Rio de Janeiro, Brazil; 5Fndn del Centro de Estudios Infectológicos, Buenos Aires, Argentina; 6Univ of São Paulo Med Sch, Brazil; 7Inst de Salud Carlos III, Madrid, Spain; and 8Bristol-Myers Squibb, Wallingford, CT, USA
5:30 pm      124 Tenofovir Disoproxil Fumarate Is Not Inferior to Adefovir Dipivoxil for the Treatment of Hepatitis B Virus in Subjects Who Are Co-infected with HIV: Results of ACTG A5127
Marion Peters*1, J Anderson2, P Lynch3, J Jacobson4, K Sherman5, B Alston Smith6, S Swindells7, T Liu2, V Johnson8, R Pollard9, J Rooney10, B polsky4, and AACTG 5127 team
1San Francisco, CA, USA; 2Boston, MA, USA; 3Chicago, IL, USA; 4New York, NY, USA; 5Cincinnati, OH, USA; 6Bethesda, MD, USA; 7Omaha, NE, USA; 8Birmingham, AL, USA; 9Univ of California, Davis, USA; and 10Foster City, CA, USA