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Session 31
Oral Abstracts
Hepatitis Virus Co-Infection
Thursday, 4 - 6 pm
Auditorium
4:00 pm 118
Comparison of Hepatitis C Virus-specific T-cell Responses in Peripheral Blood of Subjects with Chronic HCV Infection with versus without HIV Co-infection When Blocking the Cytokines Involved in Suppressor Activity
Nadia Alatrakchi*
1
, C S Graham
1
, K E Sherman
2
, and M J Koziel
1
1
Boston, MA, USA and
2
Cincinnati, OH, USA
4:15 pm 119
Evidence for a Defect in the HCV-specific CD4
+
T-cell Response in HIV/HCV Co-infected Individuals Occurring at Early Stage of HIV Infection
Valerie Dutoit*, D Ciuffreda, J J Gonvers, and G Pantaleo
Univ Hosp, Lausanne, Switzerland
4:30 pm 120
Can Routine Non-invasive Tests Predict Liver Histology in HIV/HCV Co-infection? Analysis of Patients Entering the AIDS PEGASYS Ribavirin International Co-infection Trial (APRICOT)
Richard Sterling*
1
, E Lissen
2
, N Clumeck
3
, R Sola
4
, M Correa
5
, J Montaner
6
, M Sulkowski
7
, F Torriani
8
, D Dieterich
9
, D Thomas
7
, D Messinger
10
, and M Nelson
11
1
Virginia Commonwealth Univ Hlth System, Richmond, USA;
2
Virgen del Rocío Univ Hosp, Seville, Spain;
3
Ctr Hosp Univ St-Pierre, Brussels, Belgium;
4
Hosp del Mar, Univ Autónoma de Barcelona, Spain;
5
HCFMUSP, Casa da AIDS, Sao Paulo, Brazil;
6
Univ of British Columbia, Vancouver, Canada;
7
Johns Hopkins Univ Sch of Med, Baltimore, MD, USA;
8
Univ of California, San Diego, Treatment Ctr, USA;
9
Mt Sinai Sch of Med, New York, NY, USA;
10
IST GmbH, Mannheim, Germany; and
11
Chelsea and Westminster Hosp, London, UK
4:45 pm 121
Unexpected Significant Liver Disease among HIV/HCV-coi-nfected Persons with Minimal Fibrosis on Initial Liver Biopsy
Mark Sulkowski*, S Mehta, M Torbenson, R Moore, and D Thomas
Johns Hopkins Univ, Baltimore, MD, USA
5:00 pm 122
Homosexually Transmitted HCV Acute Infection Related to a Clustered Genotype 4 HCV in HIV-1-infected Men and Inefficacy of Early Antiviral Therapy
Marie-Laure Chaix*
1
, J Serpaggi
2
, D Batisse
3
, C Dupont
4
, A Vallet-Pichard
2
, H Fontaine
2
, J P Viard
5
, C Piketty
3
, E Rouveix
4
, C Rouzioux
1
, L Weiss
3
, and S Pol
2
1
Univ Rene Descartes, Ctr Hosp Univ Necker, Paris, France;
2
INSERM U370, Ctr Hosp Univ Necker, Paris, France;
3
Ctr Hosp Univ Georges Pompidou, Paris, France;
4
Ctr Hosp Univ Ambroise Paré, Boulogne, France; and
5
Ctr Hosp Univ Necker, Paris, France
5:15 pm 123
Entecavir in HIV/HBV-co-infected Patients: Safety and Efficacy in a Phase II Study (ETV-038)
W Pessoa
1
, B Gazzard
2
, A Huang
3
, C Brandao-Mello
4
, L Cassetti
5
, M Correa
6
, V Soriano
7
, P Phiri
8
, A Hall
8
, E Ledesma
8
, and R Wilber
8
1
Inst of Infectologia 'Emilio Ribas', Sao Paulo, Brazil;
2
Chelsea and Westminster Hosp, London, UK;
3
Univ of Louisville, KY, USA;
4
Hosp Gaffrée e Guinle, Rio de Janeiro, Brazil;
5
Fndn del Centro de Estudios Infectológicos, Buenos Aires, Argentina;
6
Univ of São Paulo Med Sch, Brazil;
7
Inst de Salud Carlos III, Madrid, Spain; and
8
Bristol-Myers Squibb, Wallingford, CT, USA
5:30 pm 124
Tenofovir Disoproxil Fumarate Is Not Inferior to Adefovir Dipivoxil for the Treatment of Hepatitis B Virus in Subjects Who Are Co-infected with HIV: Results of ACTG A5127
Marion Peters*
1
, J Anderson
2
, P Lynch
3
, J Jacobson
4
, K Sherman
5
, B Alston Smith
6
, S Swindells
7
, T Liu
2
, V Johnson
8
, R Pollard
9
, J Rooney
10
, B polsky
4
, and AACTG 5127 team
1
San Francisco, CA, USA;
2
Boston, MA, USA;
3
Chicago, IL, USA;
4
New York, NY, USA;
5
Cincinnati, OH, USA;
6
Bethesda, MD, USA;
7
Omaha, NE, USA;
8
Birmingham, AL, USA;
9
Univ of California, Davis, USA; and
10
Foster City, CA, USA