| 10:00 am 146 |
CCL3L1 Gene-containing Duplications Significantly Influence Vertical Transmission
Andrea Mangano*1, E Gonzalez2, H Kulkarni2, H Bolivar2, M Dolan3,4, R Bologna1, L Sen1, and S Ahuja2
1Hosp de Pediatrķa "JP Garrahan", Buenos Aires, Argentina; 2Univ of Texas, Hlth Sci Ctr at San Antonio, USA; 3Willford Hall Med Ctr, Lackland, AFB, TX, USA; and 4Defense Inst for Med Operations, Brooks City Base, TX, USA |
| 10:15 am 147 |
HIV Co-receptor Usage Dictates Target-cics of CD4+ T-cell Depletion
Siu-hong Ho*1, L Shek1, A Gettie1, J Blanchard2, and C Cheng-Mayer1
1Aaron Diamond AIDS Res Ctr, Rockefeller Univ, New York, NY, USA and 2Tulane Natl Primate Res Ctr, Tulane Univ, Covington, LA, USA |
| 10:30 am 148 |
CD16+ Monocytes Transmit HIV-1 to CD4+ T Cells Following Cell-to-Cell Contact and Render Resting T Cells Permissive to Productive Infection by Producing Eotaxin-2 and MCP-1
Petronela Ancuta* and D Gabuzda
Dana-Farber Cancer Inst, Boston, MA, USA |
| 10:45 am 149 |
Macrophages Drive B Lymphocyte Dysfunction in HIV-1 Infection
Simon Swingler*, J Zhou, T Greenough, and M Stevenson
Univ of Massachusetts Med Sch, Worcester, USA |
| 11:00 am 150 |
Visualizing Virus Capture and Transmission by Dendritic-Cell Interference with a Fusion Inhibitor
Ines Frank*1, H Stoessel2, N Romani2, B Crise3, D Morcock3, D Ott3, E Chertova3, J Lifson3, and M Pope1
1Population Council, New York, NY, USA; 2Innsbruck Med Univ, Austria; and 3SAIC-Frederick, MD, USA |
| 11:15 am 151LB |
Polymorphism in Rhesus Macaque TRIM5 Associated with an Innate Susceptibility to SIV Infection and Disease Progression
Toshiaki Kodama*, T Kawahara, B Wahlberg, A Hartman, P Rajakumar, and M Murphy-Corb
Univ of Pittsburgh, PA, USA |
11:30 am 152
 |
Functional Differences in Dendritic-cell Populations Provide Clues to the Determinants of Divergent Disease Outcomes Following SIV Infection of Natural and Non-natural Host Species
Silvija Staprans*1, A Barry1, S Klucking1, R Chavan1, K Dalbey1, M Wernett1, H McClure2, G Silvestri1, and M Feinberg1
1Emory Univ, Atlanta, GA, USA and 2Yerkes Natl Primate Res Ctr, Emory Univ, Atlanta, GA, USA |
| 11:45 am 153 |
Effector Memory CD4+CCR5+ T Cells Are Markedly Reduced in Normal, Non-progressing Primate Host Species
Ronald Veazey*, P Marx, J Dufour, C Apetrei, A Lackner, and I Pandrea
Tulane Natl Primate Res Ctr, Tulane Univ, Covington, LA, USA |
| 12:00 pm 154 |
Relationship between Cellular Immune Responses and Viral Load in Naturally SIV-Infected Sooty Mangabeys
Zichun Wang*1, B Metcalf1, D Lee2, S Staprans2, H McClure2, and A Kaur1
1Harvard Univ, Boston, MA, USA and 2Emory Univ, Atlanta, GA, USA |
| 12:15 pm 155 |
SIV-Specific CD8 T Cell Responses are Limited in the Majority of Naturally SIV-Infected Sooty Mangabeys and their Magnitude does not Correlate with Plasma Viremia or CD4 T Cell Count
Shari Gordon*1, P Pagliardini1, B Sumpter1, J Engram1, R Dunham1, D Sodora2, M Feinberg1, S Staprans1, C Ibegbu1, and G Silvestri1
1Emory Univ, Atlanta, GA, USA and 2Univ of Texas Southwestern, Dallas, USA |
| 12:30 pm 155LB |
Discovery of New Human T-lymphotropic Viruses Reveals Frequent and Ongoing Zoonotic Retrovirus Introductions
Nathan Wolfe*1, W Heneine2, J Carr3, A Garcia2, V Shanmugam2, U Tamoufe4, J Torimiro4, A Prosser2, M LeBreton4, E Mpoudi-Ngole4, F McCutchan3, D Birx3, T Folks2, D Burke1, and W Switzer2
1Johns Hopkins Univ, Bloomberg Sch of Publ Hlth, Baltimore, MD, USA; 2CDC, Atlanta, GA, USA; 3US Military HIV Research Program, Rockville, MD, USA; and 4Johns Hopkins Walter Reed Cameroon Program, Yaounde, Cameroon |
