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Session 38
Poster Discussion
Poster Discussion: Emerging Issues in Monkey Pathogenesis Models
Friday, 2:30 - 3:30 pm
311
322
AIDS-Defining CD4
+
T-Cell Levels in the Absence of Clinical Symptoms Induced by SIVsmm Inoculation of Sooty Mangabeys
J Milush
1
, D Zhou
1
, A Muthukumar
1
, E Chacko
1
, K Cole
2
, A Barry
3
, L Demma
3
, S Staprans
3
, G Silvestri
3
, and Donald Sodora*
1
1
Univ of Texas Southwestern Med Ctr, Dallas, USA;
2
Univ of Pittsburgh, PA, USA; and
3
Emory Univ, Atlanta, GA, USA
323
Genes That May Be Involved in the Protection of SIV-infected Sooty Mangabeys from SIV Pathogenesis Revealed by Microarray Analysis
Sara Klucking*
1
, D Powell
2
, H Wu
3
, M Paiardini
1
, B Cervasi
1
, M Halloran
3
, G Silvestri
1
, S Staprans
1
, and M Feinberg
1
1
Emory Univ Vaccine Res Ctr, Atlanta, GA, USA;
2
Antigen Express Inc, Worcester, MA, USA; and
3
Emory Univ, Atlanta, GA, USA
324
Correlation of CD4+
T-Cell Depletion with Increased Levels of T-cell Activation in Naturally SIV-infected Sooty Mangabeys
B Sumpter
1
, S Gordon
1
, R Dunham
1
, P Pagliardini
1
, C Ibegbu
1
, J Engram
1
, H McClure
1
, A Muthukumar
2
, D Sodora
2
, M Feinberg
1
, S Staprans
1
, and Guido Silvestri*
1
1
Emory Univ, Atlanta, GA, USA and
2
Univ of Texas Southwestern, Dallas, USA
325
New Model for the Study of SIV Pathogenesis in Natural Host Species: Infection of Carribean African Green Monkeys with SIVagm.sab
I Pandrea
1
, C Apetrei
1
, J Dufour
1
, N Dillon
1
, B Poonia
1
, O Diop
2
, M Muller-Trutwin
3
, R Bohm
1
, P Marx
1
, A Lackner
1
, and Ronald Veazey*
1
1
Tulane Natl Primate Res Ctr, Tulane Univ, Covington, LA, USA;
2
Inst Pasteur, Dakar, Senegal; and
3
Inst Pasteur, Paris, France
326
AIDS in African Nonhuman Primate Species: Pathological Findings
I Pandrea, X Alvarez, B Gormus, C Apetrei, V Traina-Dorge, P Marx, G Baskin, A Lackner, and Ronald Veazey*
Tulane Natl Primate Res Ctr, Tulane Univ, Covington, LA, USA
327
SIV Adaptation to a New Host Involves the Preferential Amplification of a Discrete Subset of Envelope Genotypes from within the Diverse Viral Quasi-species
L Demma
1
, J Logsdon
2
, Thomas Vanderford*
3
, M Feinberg
4
, and S Staprans
5
1
CDC, Atlanta, GA, USA;
2
Univ of Iowa, Iowa City, USA;
3
Emory Univ, Atlanta, GA, USA ;
4
Merck & Co, West Point, PA, USA; and
5
Emory Univ, Atlanta, GA, USA
328
Howerton
Binhua Ling*, R Veazey, L Martin, and P Marx
Tulane Natl Primate Res Ctr, Tulane Univ, Covington, LA, USA