Session 50 - 12th CROI

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Session 50 Poster Abstracts
Viral Replication: Early Events, Fusion, and Tropism
Wednesday, 1:30 - 3:30 pm
Hall D

200	CXCR4-tropic HIV-1 Envelope Glycoprotein Functions as a Viral Chemokine in Unstimulated Primary CD4+ T Lymphocytes K Balabanian, J Harriague, C Decrion, B Lagane, S Shorte, F Baleux, J L Virelizier, F Arenzana-Seisdedos, and Lisa Chakrabarti* Inst Pasteur, Paris, France
201	Cryo-electron Microscopy of HIV-1 and SIV Surfaces Ping Zhu*¹, E Chertova², J Bess², J Liu¹, K Taylor¹, J Lifson², L Arthur², and K Roux¹ ¹Florida State Univ, Tallahassee, USA and ²NCI-Frederick, NIH, DHHS, MD, USA
202	HIV-1 Exploits Host Sulfations to Facilitate Its Entry into Human Cells M Bobardt, A Parseval, J Elder, and Philippe Gallay* The Scripps Res Inst, La Jolla, CA, USA
203	Restricted Variable Residues in the Stem of HIV-1 V3 Loop Regulate Molecular Anatomy of CCR5 Utilization Q Hu*¹, K Napier², J Trent², Z Wang³, S Taylor⁴, G Griffin¹, S Peiper³, and R Shattock¹ ¹St George's Hosp Med Sch, London, UK; ²Brown Cancer Ctr, Univ of Louisville, KY, USA; ³Med Coll of Georgia, Augusta; and ⁴Univ of Birmingham, UK
205	Predicted Co-receptor Usage of HIV-1 in Low-level Viremias during HAART Nicole Tobin*, M Jensen, G Learn, J Mullins, and L Frenkel Univ of Washington, Seattle, USA
206	A Single Amino Acid Substitution in the HIV-1 gp41 Cytoplasmic Domain Affects Assembly of a Patient-Derived Envelope Glycoprotein Jayanta Bhattacharya*, J M Jacque, and P Clapham Univ of Massachusetts Med Sch, Worcester, USA
207	Generation of a Temperature Arrested Intermediate of HIV Virus-Cell Fusion Hamani Henderson* and T Hope Univ of Illinois, Chicago, USA
208	Characterization of HIV Receptor and Co-receptor Dynamics Using Photoactivatable GFP Andrea D Anderson*, C Steffens, and T Hope Univ of Illinois, Chicago, USA
209	sCD4 Induces Exposure of the HIV-1 gp41 Pre-hairpin Intermediate in the Absence of gp120 Dissociation Nicole Kilgore*, K Salzwedel, M Reddick, and C Wild Panacos Pharma, Inc, Gaithersburg, MD, USA
210	Selection of Peptides that Interfere with HIV-1 Infection and Isolation of Host Cellular Factors Involved Roland Wolkowicz*, G Jager, and G Nolan Stanford Univ Med Ctr, CA, USA
211	Replication Competent Variants of HIV-2 with Deletions of the V1/V2 and V3 Hypervariable Loops George Lin*^1,2, A Bertolotti-Ciarlet², M Biscone², B Haggarty², J Romano², J Reeves², J Miamidian², R Doms², and J Hoxie² ¹Biological Mimetics, Inc, Frederick, MD, USA and ²Univ of Pennsylvania, Philadelphia, USA
212	Stoichiometric Requirements of Envelope Glycoproteins in the Entry of HIV-I, Amphotropic Murine Leukemia Virus, and Influenza A Virus Xinzhen Yang*, S Kurteva, X Ren, S Lee, and J Sodroski Dana-Farber Cancer Inst, Boston, MA, USA
213	Preferential Use of CXCR4 by R5X4 HIV-1 Isolates for Infection of Primary Lymphocytes Yanjie Yi*, F Shaheen, and R Collman Univ of Pennsylvania, Philadelphia, USA
214	HIV-1 Envelope gp120 Determinants of CXCR4-Mediated Infection of Macrophages G Ghaffari¹, D Tuttle¹, Joshua Bunger*², J Sleasman³, and M Goodenow³ ¹Univ of Florida, Gainesville, USA; ²Univ of Florida, Gainesville, USA; and ³Univ of Florida, Gainesville, USA
215	A Reliable Co-receptor Usage Predictor for HIV-1 Subtype C Based on Env V3 Sequence Mia Coetzer*¹, M Jensen², A van 't Wout³, L Morris¹, and J Mullins³ ¹Natl Inst for Communicable Diseases, Johannesburg, South Africa; ²Emory Univ, Atlanta, GA, USA ; and ³Univ of Washington, Seattle, USA
216	Phenotypic Characterization of Human Immunodeficiency Virus Type I (HIV-1) Envelopes Derived from Kidney and Blood of Patients with Renal Diseases B Zerhouni-Layachi, P Klotman, and Mary E Klotman* Mt Sinai Sch of Med, New York, NY, USA
217	A HIV-1 Minimal Gag Protein Is Superior to NC at in vitro tRNALys3 Annealing and Exhibits Multimerization-induced Inhibition of Reverse Transcription Ariel Roldan*, B Spira, O Warren, R Russell, C Liang, and M Wainberg McGill Univ AIDS Ctr, Montreal, Canada
218	Intracytoplasmic Maturation of the HIV-1 Pre-integration Complexes Determines Their Capacity to Integrate into Chromatin Sergey Iordanskiy*, R Berro, F Kashanchi, and M Bukrinsky George Washington Univ, Washington, DC, USA
219	Specific Intersubunit Trp-motif Interactions Are Critical for HIV-1 RT Function in vivo Alok Mulky*¹, S Sarafianos², Y Jia¹, E Arnold², and J Kappes¹ ¹Univ of Alabama at Birmingham, USA and ²Rutgers Univ, Piscataway, NJ, USA