Session 58 - 12th CROI

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Session 58 Poster Abstracts
Virus-Macrophage Interactions
Thursday, 1:30 - 3:30 pm
Hall D

278	CCR5 Signaling-induced ERK1/2 Activation Boosts R5 HIV-1 Replication in Primary Mononuclear Cells G Y L Lin¹, C Mettling¹, B Réant¹, J Clot², and Pierre Corbeau*¹ ¹Inst de Génétique Humaine, CNRS UPR1142, Montpellier, France and ²Hosp St Eloi, Montpellier, France
279	gp120 Stimulation of TNF-aalpha Production by Human Macrophages Is Mediated by CCR5 through a PI-3 Kinase and MAPK Kinase-Dependent Pathway Brian E Tomkowicz*, C Lee, and R Collman Univ of Pennsylvania, Philadelphia, USA
280	HIV-1 Induces Changes in Genetic Networks Involved in Immune Function, Signal Transduction, and a Th2-type Shift in Cytokine Secretion in Human Macrophages James Kohler*¹, J Brown¹, C Coberley¹, J Sleasman², and M Goodenow¹ ¹Univ of Florida, Gainesville, USA and ²Univ of South Florida, St Petersburg, USA
281	Selective Removal of Superoxide Anions Is Crucial for HIV Replication in Human Primary Macrophages and Prevents Peroxynitrite-Mediated Apoptosis in Neurons Stefano Aquaro*¹, C Muscoli², M Pollicita¹, A Ranazzi¹, T Granato³, M C Bellocchi¹, A Modesti¹, D Salvemini⁴, V Mollace², and C F Perno^5,6 ¹Univ of Rome 'Tor Vergata', Italy; ²Univ of Catanzaro Magna Grecia, Roccelletta di Borgia, Italy; ³Inst of Molecular Bio and Pathology, Natl Res Council, Rome, Italy; ⁴Metaphore Pharma, St Louis, MO, USA; ⁵INMI L Spallanzani, Rome, Italy; and ⁶Univ of Rome 'Tor Vergata', Italy
282	HIV-1 Nef Protein Interferes with M-CSF Receptor Signallng through Hck Activation and Inhibits M-CSF Bioactivities Shinya Suzu*, H Harada, and S Okada Kumamoto Univ Sch of Med, Japan
283	Activation of Toll-like Receptor-3-induced anti-HIV Activity in Primary Human Macrophages Xinyan Liu*¹, A Mosoian¹, T Chang¹, C Vogel¹, G Jarvis², and M Klotman¹ ¹Mt Sinai Sch of Med, New York, NY, USA and ²Univ of California, San Francisco, USA
284	Independent Evolution of HIV-1 between Blood Monocytes and CD4+ T Cells during the Course of the Infection with and without Antiretroviral Therapy Rafael Zioni*, Y Hwangbo, H Zhu, J Fulcher, X Lin, L Corey, and T Zhu Univ of Washington, Seattle, USA