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Session 62
Poster Abstracts
Viral Reservoir Characterization
Thursday, 1:30 - 3:30 pm
Hall D
297
Modeling T-cell Receptor Excision Circles and 5-bromo-2'-deoxyuridine Labeled Naive T Cells during Highly Active Antiretroviral Therapy
Michele Di Mascio*
1
, I Sereti
1
, L Matthews
1
, V Natarajan
2
, C Yoder
1
, E Jones
3
, C Chow
3
, J Metcalf
1
, M Polis
1
, I Sidorov
4
, D Dimitrov
4
, and J Kovacs
3
1
NIAID, Bethesda, MD, USA;
2
SAIC-Frederick, MD, USA;
3
Clin Ctr, Natl Inst of Hlth, Bethesda, MD, USA; and
4
NCI-Frederick, NIH, DHHS, MD, USA
298
Persistence of Archived Viruses with a Unique Tropism in Antiretroviral-Treated Individuals with Drug-Resistant HIV
Wei Huang*
1
, T Neilands
2
, J Whitcomb
1
, T Wrin
1
, J Toma
1
, S Fransen
1
, J Martin
2
, C Petropoulos
1
, and S Deeks
2
1
ViroLogic, Inc, South San Francisco, CA, USA and
2
Univ of California, San Francisco, USA
299
IL-7 as a Potent Inducer of Viral Strain-specific HIV-1 Reservoirs
Roger Pomerantz*
1
, F X Wang
1
, Y Xu
1
, J Sullivan
1
, E Sounder
1
, E Argyris
1
, E Acheampong
1
, J Fisher
1
, M Sierra
2
, R Najera
2
, J Kulkosky
1
, and G Nunnari
1
1
Thomas Jefferson Univ, Philadelphia, PA, USA and
2
Inst de Salud Carlos III, Majadahonda, Spain
300
Blood Monocytes Harbor Viruses Utilizing Multiple Coreceptors
Younong Xu*
1
, H Zhu
1
, A Van't Wout
1
, J Lee
2
, C Dai
1
, M Jenkins
1
, T Andrus
1
, N Llewellyn
1
, R Zioni
1
, L Stamatatos
1
, J Mullins
1
, M McElrath
2
, L Corey
3,4
, and T Zhu
3,4
1
Univ of Washington, Seattle, USA;
2
Fred Hutchinson Cancer Res Ctr, Seattle, WA, USA;
3
Univ of Washington, Seattle, USA; and
4
Fred Hutchinson Cancer Res Ctr, Seattle, WA, USA
301
In Vivo
Evidence for Instability of Episomal HIV-1 cDNA
Mark Sharkey*
1
, K Triques
1
, D Kuritzkes
2
, and M Stevenson
1
1
UMass Medical Center, Worcester, MA USA and
2
Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA USA
302
Decay Kinetics of PBMC with Different HIV-RNA Expression Patterns Measured at the Single-cell Level Using Limiting Dilution Combined with Patient Matched Real-time PCR
Marek Fischer*
1
, P Kaiser
1
, D Baumann
1
, R Hafner
1
, C Schneider
1
, S Bonhoeffer
2
, R Weber
1
, and H Guenthard
1
1
Zurich Univ Hosp, Switzerland and
2
ETH Zurich, Switzerland
303
A Novel Culture System that Allows HIV-infected Activated Primary CD4
+
T-lymphocytes to Become Latently-infected Quiescent Cells
Gautam Sahu*, J Ji, and M Cloyd
Univ of Texas Med Branch, Galveston, USA
304
Defining Functionally Significant Reservoirs for HIV-1 in Patients on HAART
T Kieffer, R Nettles, H Zhang, Y Han, Y Liu, J Bailey, C Haggerty, M Wind-Rotolo, D Persaud, T Quinn, J Siliciano, and S Ray
Johns Hopkins Univ, Baltimore, MD, USA