Session 73 - 12th CROI

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Session 73 Poster Abstracts
Neuropathogenesis: Virology
Thursday, 1:30 - 3:30 pm
Hall D

374	A Rare and Extreme Etiology of HIV-1 in the Cerebrospinal Fluid and Blood in an HIV-infected Non-progressor Bin Wang*¹, M Mikhail¹, W Dyer², J Zaunders³, D Cooper³, A Kelleher³, B Brew⁴, and N Saksena¹ ¹Westmead Millennium Inst, Westmead Hosp, Univ of, Sydney, Australia; ²Australian Red Cross, Sydney; ³St Vincent's Hosp, Darlinghurst, Australia; and ⁴St Vincent's Hosp, Sydney, Australia
375	Phylodynamic Analysis of HIV-1 in the Brain M Salemi¹, S Lamers², S Yu³, T de Oliveira⁴, W Fitch⁵, and Michael McGrath*³ ¹Univ of Florida, Gainesville, USA; ²Gene Johnson Inc, St Augustine, FL, USA; ³Univ of California, San Francisco, USA; ⁴Univ of California, Irvine, USA; and ⁵Africa Ctr for Hlth and Population Studies and Nelson Mandela Sch of Med, Durban, South Africa
376	A Genetic Variant of HIV with Reduced CD4 Dependence Is Associated with Brain Infection and HIV-associated Dementia Rebecca Dunfee*^1,2, E Thomas^1,2, P Gorry^1,2, J Taylor³, K Kunstman³, J Bell⁴, S Wolinsky³, and D Gabuzda^1,2 ¹Dana-Farber Cancer Inst, Boston, MA, USA; ²Harvard Med Sch, Boston, MA, USA; ³Northwestern Univ, Feinberg Sch of Med, Chicago, IL, USA; and ⁴Univ of Edinburgh, Scotland
378	Astrocytes Constitute a Unique Central Nervous System HIV Reservoir in Persons with Suppressed Plasma Virus and Elevated CD4+ Cell Counts Nikilyn Kinzel*¹ and W Cavert² ¹Mayo Grad Sch, Rochester, MN, USA and ²Univ of Minnesota, Minneapolis, USA
379	Establishment of Persistent Inducible Latent HIV Infection in Astrocytes: Relevance to the HIV Reservoir in Brain Ashok Chauhan*, S Gartner, and A Nath Johns Hopkins Univ, Baltimore, MD, USA and Johns Hopkins Univ, Baltimore, MD, USA
380	Regulation of HIV-1 Transcription by NF-kB, SP-1, and Histone Acytelation in Primary Human Astrocytes Elena Paskaleva*, D Avram, and M Canki Albany Med Coll, NY, USA and Albany Med Coll, NY, USA
381	Molecular Mechanisms for HIV-1 Restriction in Human Astroglia Roger Pomerantz*, J Fang, E Acheampong, and M Mukhtar Thomas Jefferson Univ, Philadelphia, PA, USA
382	HIV-1 Nef Potently Induces Apoptosis at the Blood-Brain Barrier Roger Pomerantz*, E Acheampong, Z Parveen, L Muthoga, M Kalayeh, and M Mukhtar Thomas Jefferson Univ, Philadelphia, PA, USA
383	Potently Targeting Neurotropic HIV-1 Strains with RNA Interference in Human Macrophages Rajnish S Dave* and R Pomerantz Thomas Jefferson Univ, Philadelphia, PA, USA
384	Enhanced Replication of Human Polyomavirus JC Type 2B in Primary Glial Cells Vivek Nerurkar*¹, R Frisque², T Bui¹, and S Tyagarajan² ¹Univ of Hawaii, Honolulu, USA and ²Pennsylvania State Univ, University Park, USA