Session 74 - 12th CROI

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Session 74 Poster Abstracts
Neuropathogenesis: Host Co-Factors
Thursday, 1:30 - 3:30 pm
Hall D

385	Promyelocytic Leukemia Protein Contributes to the Non-permissive Astrocytic Infection by HIV David Galey*, A Chauhan, G Hayward, and A Nath Johns Hopkins Univ, Baltimore, MD, USA
386	A Quantitative and Topographic Analysis of Neuroglial Reactions in HIV Dementia Adrea Lee*¹, D Vargas¹, C Nascimbene^1,2, L Guo¹, J Williams³, and C Pardo¹ ¹Johns Hopkins Univ Sch of Med, Baltimore, MD, USA; ²Univ of Milan, Italy; and ³Johns Hopkins Univ, Bloomberg Sch of Publ Hlth, Baltimore, MD, USA
387	Effect of HIV-1 Primary Isolates on Monocyte Proteome and Neurovirulence from Hispanic women with Cognitive Impairment Dianedis Toro*¹, E Anderson¹, M Plaud¹, E Rodríguez¹, V Wojna¹, P Ciborowski², H Gendelman², and L Meléndez¹ ¹Univ of Puerto Rico, Med Sci Campus, San Juan and ²Univ of Nebraska Med Ctr, Omaha, USA
388	Mechanisms of HIV-induced Neurodegeneration: Role of NMDA Receptor Subtypes in Communicating Neuronal Cell Death Lauren A O'Donnell*¹, A Agrawal¹, D Lynch^2,3, M Dichter¹, and D Kolson¹ ¹Univ of Pennsylvania, Philadelphia, USA; ²Univ of Pennsylvania, Philadelphia, USA; and ³Children's Hosp of Philadelphia, PA, USA
389	TRAIL Conditionally Induces Apoptosis in Human Neural Progenitor Cells: Linkage to the Pathogenesis of HIV-1-associated Dementia Hui Peng*, Y Huang, A Lopez, D Xu, A Ghorpade, and J Zheng Univ of Nebraska Med Ctr, Omaha, USA
390	Exogenous IL-7 Induces Neuronal Apoptosis: Molecular Mechanisms During HIV-1 Infection Yan Xu*, E Acheampong, R Daniel, J Fang, C Zhang, M Mukhtar, G Nunnari, and R Pomerantz Thomas Jefferson Univ, Philadelphia, PA, USA
391	Statins Block Enhanced Transvascular Migration of HIV-1-infected Cells: A Novel Therapeutic Approach for HIV-1 Neuroinvasion Muhammad Mukhtar*¹, A Mengistu², E Acheampong¹, J Sullivan¹, G Nunnari¹, E Argyris¹, M Kalayeh¹, K Williams¹, and R Pomerantz¹ ¹Thomas Jefferson Univ, Philadelphia, PA, USA and ²Johns Hopkins Univ, Baltimore, MD, USA
392	Gene Expression in Cerebral Endothelial Cells Treated with the HIV Protease Inhibitor Indinavir Aline Grigorian*, R Hurford, Y Chao, C Patrick, and D Langford Univ of California, San Diego, USA
393	HIV-1-infected Macrophages Cause Mitochondrial Impairment in Human Dorsal Root Ganglia Neuronal Cultures Katrin Hahn*, B Robinson, C Anderson, D Galey, S Gartner, and A Nath Johns Hopkins Univ Sch of Med, Baltimore, MD, USA
394	Neuropathogenic Effects of HIV-1 on Dorsal Root Ganglion Neurons: Pro-inflammatory Cytokine Induction and Neuronal Degeneration Gareth Jones*¹, Y Zhu¹, S Tsutsui¹, J McArthur², C Pardo², O Keppler³, and C Power¹ ¹Univ of Calgary, Alberta, Canada; ²Johns Hopkins Univ, Baltimore, MD, USA; and ³Univ of Heidelberg, Germany
395	in vitro Models of HIV-associated Neuropathies Differ in Pathogenic Site of Action Giorgia Melli* and A Hoke Johns Hopkins Univ, Baltimore, MD, USA
396	Development of a Small Rodent Model of HIV-associated Sensory Neuropathies C Jack, C Zhou, G Melli, S Keswani, and Ahmet Hoke* Johns Hopkins Univ, Baltimore, MD, USA