Session 90 - 12th CROI

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Session 90 Poster Abstracts
HIV-1 Neutralizing Antibodies
Wednesday, 1:30 - 3:30 pm
Hall D

497a	Antigenic and Immunogenic Analysis of Hepatitis B Surface Antifgen Particles Containing HIV gp41-Membrane Proximal Region Sanjay Phogat*¹, A Spadaccini², I Berkower², and R Wyatt¹ ¹Vaccine Res Ctr, NIAID, NIH, DHHS, Bethesda, MD, USA and ²Center For Biologics, FDA, Bethesda, MD
497b	Use of Directed Molecular Evolution to Create Novel HIV-1 Envelope Variants Capable of Inducing Broadly Neutralizing Antibody Responses in Rabbits X Du¹, L Xu¹, W Zhang¹, S Tang¹, J Harms², R Robson², M Chambers², T Wrin³, C Petropoulos³, M Zwick⁴, D Burton⁴, and Robert Whalen*¹ ¹Maxygen Inc, Redwood City, CA, USA; ²Aldevron LLC, Fargo, ND, USA; ³ViroLogic, Inc, South San Francisco, CA, USA; and ⁴The Scripps Res Inst, La Jolla, CA, USA
498	Novel Broadly Cross-reactive Anti-gp41 HIV-1 Neutralizing Human Monoclonal Antibodies Selected from Phage Display Libraries by Competitive Antigen Panning Mei-Yun Zhang*¹, V Choudhry¹, I Sidorov¹, S Stefanov¹, V Tenev¹, C Broder², and D Dimitrov¹ ¹NCI-Frederick, NIH, DHHS, MD, USA and ²Uniformed Svcs Univ of the Hlth Sci, Bethesda, MD, USA
499	Antigenic and Immunogenic Properties of Disulfide-stabilized HIV-1 Envelope Trimers Norbert Schülke*¹, S Beddows², M Franti¹, T Zang¹, I Vishnefsky¹, T Ketas¹, K Barnes², E Michael², J Moore², P Maddon¹, and W Olson¹ ¹Progenics Pharma, Inc, Tarrytown, NY, USA and ²Weill Med Coll, Cornell Univ, New York, NY, USA
500	Neutralization and Infectivity Characteristics of Envelope Glycoproteins from Human Immunodeficiency Virus Type 1- infected Donors Whose Sera Exhibit Broadly Cross-reactive Neutralizing Activity Fatim Cham*¹, P Zhang¹, L Heyndrickx², P Bouma¹, M Zwick³, D Burton³, H Katinger⁴, J Robinson⁵, S Zolla-Pazner⁶, G van der Groen⁷, and G Quinnan⁸ ¹Uniformed Svcs Univ of the Hlth Sci, Bethesda, MD, USA; ²Inst of Tropical Med, Anwerp, Belgium; ³The Scripps Clin and Res Fndn, La Jolla, CA, USA; ⁴Inst of Applied Microbiology, Univ of Life Sci, Vienna, Ausria; ⁵Tulane Univ, New Orleans, LA, USA; ⁶New York Veterans Admin Med Ctr, NY, USA; ⁷Inst of Tropical Med, Anwerp, Belgium; and ⁸Uniformed Svcs Univ of the Hlth Sci, Bethesda, MD, USA