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Session 112  Poster Abstracts
Pharmacology of NNRTIs
Wednesday, 1:30 - 3:30 pm
Hall A
      650 Relevance of Drug Transporters and Drug Metabolism Enzymes to Nevirapine: Superimposition of Host Genotype
Andrew Owen*1, L Almond1, R Hartkoorn1, T Walsh1, M Youle2, A Bonington3, F Turner2, C Smith2, A M Garretti2, A Phillips2, O Janneh1, D Back1, and S Khoo1
1Liverpool Univ, UK; 2Royal Free Hosp, London, UK; and 3North Manchester Gen Hosp, UK
      651 Pharmacogenetics of Efavirenz and Selective Pressure for Drug Resistance after Treatment Discontinuation: NWCS214, an Analysis of ACTG Studies A5095/A5097S
David W Haas*1, H Ribaudo2, R Kim1, C Tierney2, G Wilkinson1, R Gulick3, D Clifford4, C Marzolini1, and E Acosta5
1Vanderbilt Univ, Nashville, TN, USA; 2Harvard Sch of Publ Hlth, Boston, MA, USA; 3Weill Med Coll, Cornell Univ, New York, NY, USA; 4Washington Univ Sch of Med, St Louis, MO, USA; and 5Univ of Alabama at Birmingham, USA
      652

G516T Polymorphism at the CYP2B6 Isoenzyme Significantly Influences Efavirenz Plasma Levels and the Risk of Neurological Symptoms
Sonia R-Novoa*, P Barreiro, A Rendon, J Gonzalez-Lahoz, and V Soriano
Hosp Carlos III, Madrid, Spain
      653

Efavirenz Decreases Buprenorphine Exposure, but Is Not Associated with Opiate Withdrawal in Opioid Dependent Individuals
EF McCance-Katz*1, P Pade1, G Friedland2, G Morse3, D Moody4, and P Rainey5
1Richmond, Virginia; 2New Haven, CT, USA; 3Buffalo, NY, USA; 4Salt Lake City, Utah; and 5Seattle, Washington