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Session 144
Poster Abstracts
Pharmacogenetics of NNRTI Hepatoxicity
Wednesday, 1:30 - 3:30 pm
Hall B
832
Genetic Variation in Drug Transporter and Metabolizing Enzyme Genes May Be Associated with Non-Nucleoside Reverse Transcriptase Inhibitor Hepatotoxicity
Marylyn Ritchie*
1
, D Haas
1
, A Motsinger
1
, J Donahue
1
, H Erdem
1
, S Raffanti
2
, A George
1
, R Kim
1
, J Haines
1
, and T Sterling
1
1
Vanderbilt Univ, Nashville, TN, USA and
2
Vanderbilt Univ, Nashville, TN, USA
833
Pharmacogenetics of Nevirapine and Hepatotoxicity: NWCS220, an ACTG Collaborative Study
David W Haas*
1
, J Bartlett
2
, J Andersen
3
, I Sanne
4
, G Wilkinson
1
, J Quinn
5
, F Rousseau
5
, C Ingram
1
, A Shaw
5
, M Lederman
6
, and R Kim
1
1
Vanderbilt Univ, Nashville, TN, USA;
2
Duke Univ Med Ctr, Durham, NC, USA;
3
Harvard Sch of Publ Hlth, Boston, MA, USA;
4
Univ of the Witwatersrand, Johannesburg, South Africa;
5
Gilead Sci, Foster City, CA, USA; and
6
Case Western Reserve Univ, Cleveland, OH, USA