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Session 160
Poster Abstracts
HCV Immune Responses
Wednesday, 1:30 - 3:30 pm
Hall B
913
Increased Hepatocyte Fas Expression and Apoptosis in HIV/HCV-co-infected Patients
Juan Macías*
1
, M Japón
2
, C Sáez
2
, R Palacios
1
, N Merchante
1
, J Mira
1
, J García-García
1
, S Vergara
1
, F Lozano
3
, J Gómez-Mateos
3
, and J Pineda
4
1
Hosp Univ de Valme, Seville, Spain;
2
Hosp Univ Virgen del Rocío, Seville, Spain;
3
Hosp Univ de Valme, Seville, Spain; and
4
Hosp Univ de Valme, Seville, Spain
914
The Tandem-Repeat Polymorphism of the DC-SIGNR Gene in HCV and HCV/HIV Infection
Jacob Nattermann*
1
, G Ahlenstiel
1
, H Nischalke
1
, G Feldmann
1
, T Berg
2
, T Sauerbruch
1
, J Rockstroh
1
, U Spengler
1
, and Kompetenznetz HIV/AIDS
1
Univ of Bonn, Germany and
2
Humboldt Univ, Berlin, Germany
915
Induction of Effector T-cell Responses following Acute Hepatitis C Virus Infection in HIV-1
+
Individuals
Arthur Kim*
1
, J Timm
1
, J Schulze zur Wiesch
1
, G Alter
1
, M Brockman
1
, J Duncan
1
, A Jones
1
, J Fangman
1
, A Wurcel
2
, B McGovern
2
, G Robbins
1
, M Addo
1
, G Lauer
1
, and B Walker
1
1
Partners AIDS Res Ctr, Massachusetts Gen Hosp, Boston, USA and
2
Lemuel Shattuck Hosp, Jamaica Plain, MA, USA
916
HIV Co-infection Impairs CD28 Mediated Co-stimulation of HCV-specific CD8 Cells
N Yonkers
1
, B Rodriguez
1,2
, A Post
2,4
, R Asaad
1,2
, L Jones
3
, M Lederman
1,2
, P Lehmann
1
, and Donald Anthony*
1,3
1
Case Western Reserve Univ, Ctr For AIDs Res, Cleveland, OH, USA;
2
University Hospitals;
3
VA Med Ctr, Cleveland, OH, USA; and
4
Case Western Reserve Univ, Cleveland, OH, USA
917
Sequence Convergence and Cellular Immune Escape during Acute Human Hepatitis C
Andrea Cox*, Q Mao, T Mosbruger, D Netski, X H Wang, D Pardoll, D Thomas, and S Ray
Johns Hopkins Univ, Baltimore, MD, USA
918
Neutralizing Antibodies in Acute and Early Hepatitis C Virus Infection
Dale Netski*
1
, J McKeating
2
, K Dowd
1
, D Thomas
1
, and S Ray
1
1
Johns Hopkins Univ Sch of Med, Baltimore, MD, USA and
2
Rockefeller Univ, New York, NY, USA
919
Role of MHC Class I-associated Selection Pressures in Influencing HCV Evolution
Joerg Timm*
1,5,6
, A Kim
1,5,6
, L Reyor
1,5,6
, G Lauer
1,5,6
, R Allgaier
1,5,6
, R Gandhi
5,6
, R Chung
3,6
, P Klenerman
4
, B Walker
1,5,6
, and T Allen
1,5,6
1
Howard Hughes Med Inst, Boston, MA, USA;
3
Massachusetts Gen Hosp, Boston, USA;
4
Univ of Oxford, UK;
5
Partners AIDS Res Ctr, Massachusetts Gen Hosp, Boston, USA; and
6
Harvard Med Sch, Boston, MA, USA
920
Differential Effects of Ethanol Consumption on Antigen-specific Cellular Immune Responses in HIV/HCV- vs HCV-infected Subjects
Camilla Graham*
1,2
, A Wells
1
, J Murray
3
, T Herren
3
, S Tumilty
4
, S Stuver
3
, D Craven
5
, D Nunes
4
, R Horsburgh
4,6
, and M Koziel
1,2
1
Beth Israel Deaconess Med Ctr, Boston, MA, USA;
2
Harvard Med Sch, Boston, MA, USA;
3
Boston Univ, MA, USA;
4
Boston Med Ctr, MA, USA;
5
Lahey Clin Med Ctr, Burlington, MA, USA; and
6
Boston Univ, MA, USA
921
Effect of Human Herpesvirus 8 and Hepatitis C Virus Co-infection on T-cell Activation among HIV-infected Patients
Peter Hunt*, S Deeks, A Graves-Jones, E Sinclair, B Bredt, and J Martin
Univ of California, San Francisco, USA