Session 64 - 12th CROI

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Session 64 Poster Abstracts
Virus-Host Interactions: Antiviral Responses and Mucosal Infection
Wednesday, 1:30 - 3:30 pm
Hall D

310	Negative HIV Antibody Test and Negative Viral RNA in a Patient with Documented HIV Infection Itzchak Levy*¹, G Rahav¹, M Bakhanashwili¹, E Nadir¹, and Z Grossman² ¹ Infectious disease unit, Sheba medical center, Tel Hashomer, Israel and ²Natl HIV Reference Ctr, Tel Hashomer, Israel
311	a--defensin-1 Has a Dual Role in Anti-HIV-1 Innate Immunity: Effects on the Virion and the Cell T Chang, J Vargas, Jr, A DelPortillo, and Mary Klotman* Mt Sinai Sch of Med, New York, NY, USA
312	GB Virus C Envelope Glycoprotein E2 Elicits Antibodies That Immunoprecipitate HIV Particles and Neutralize HIV Infectivity Jinhua Xiang*¹, J McLinden¹, Q Chang¹, D Klinzman¹, T Kaufman¹, A Engel², G Hess³, D Zdunek², and J Stapleton¹ ¹Iowa City VA Med Ctr and Univ of Iowa, USA; ²Roche Diagnostics, Penzburg, Germany; and ³Roche Diagnostics, Mannheim, Germany
313	Human a-Defensin-1 and Rhesus t-Defensin-1 Inhibit HIV-1 Replication by Different Mechanisms Aprille Matthews*, L White, P Tran, M Selsted, and D Camerini Univ of California, Irvine, USA
314	Mucosal CD4+ T-cell Restoration and Antigen-Specific T-cell Responses in HIV-1-infected Individuals Initiating Therapy during Primary vs Chronic Infection Moraima Guadalupe*¹, E Reay¹, S Sankaran¹, T Prindiville¹, J Flamm², B Shacklett¹, and S Dandekar¹ ¹Univ of California, Davis, USA and ²Permanente Med Group, Sacramento, CA, USA
315	CD4⁺CD25^+hiT Regulatory-Cell Dynamics during Acute and Chronic HIV Infection, and Response to Therapy Anita Shet*¹, S Mehandru¹, P Lopez¹, A Horowitz¹, A Hurley¹, D Unutmaz², D Boden¹, and M Markowitz¹ ¹Aaron Diamond AIDS Res Ctr, Rockefeller Univ, New York, NY, USA and ²Vanderbilt Univ, Nashville, TN, USA
316	Parallel HIV-1-Specific CD8+ T-Lymphocyte Responses in Blood and Mucosa during Chronic Infection F Javier Ibarrondo*¹, P Anton¹, M Fuerst¹, H Ng¹, J Wong², J Matud¹, J Elliott¹, R Shih¹, M Hausner¹, C Price¹, L Hultin¹, B Jamieson¹, and O Yang¹ ¹Geffen Sch of Med, Univ of California, Los Angeles, USA and ²Massachusetts Gen Hosp, Harvard Med Sch, Boston, USA
317	Cellular Resistance to HIV-1 Infection May Explain Continued Seronegativity in Select Highly Exposed Individuals Emily Speelmon*^1,2, D Livingston-Rosanoff², D Wick², J Lee², and M McElrath^1,2 ¹Univ of Washington, Seattle, USA and ²Fred Hutchinson Cancer Res Ctr, Seattle, WA, USA
318	Synthetic t-Defensins, which Inhibit HIV-1 Entry, Exhibit Different Activity against Primary HIV-2 and SIV Isolates Silvina Masciotra*¹, S Kennedy¹, D Rudolph¹, W Wang², A Cole³, A Waring², R Lal¹, R Lehrer², and M Owen¹ ¹Ctr for Dis Control and Prevention, Atlanta, GA, USA; ²Univ of California, Los Angeles, USA; and ³Univ of Central Florida, Orlando, USA
319	Early Antiretroviral Therapy in Simian Immunodeficiency Virus Infection Leads to Mucosal CD4⁺ T-cell Restoration and Enhanced Gene Expression Regulating Mucosal Repair and Regeneration Michael George*, E Reay, S Sankaran, and S Dandekar Univ of California, Davis, USA
320	CCR5 Expression in Blood and Cervical Tissue of Healthy Women Kavita Marfatia*¹, F Priddy², G Silvestri¹, and M Feinberg¹ ¹Emory Univ Vaccine Res Ctr, Atlanta, GA, USA and ²Emory Univ Hope Clin, Atlanta, GA, USA
321	Visualizing Individual, Fluorescently Tagged HIV-1 Penetration in a Cervical Explant Model Tracy Schmidt*, E Forde, and T Hope Univ of Illinois at Chicago, USA