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Session 114  Poster Abstracts
Pharmacology: Entry Inhibitors and P-Glycoprotein
Friday, 1:30 - 3:30 pm
Hall A
      663

A Novel Probe Drug Interaction Study to Investigate the Effect of Selected ARV Combinations on the Pharmacokinetics of a Single Oral Dose of UK-427,857 in HIV + ve Subjects
G Muirhead1, Anton Pozniak*2, B Gazzard2, M Nelson2, G Moyle2, C Ridgway1, R Taylor-Worth1, and D Russell1
1Pfizer Global Res and Devt, Sandwich, UK and 2Chelsea and Westminster Hosp, London, UK
      664

The Pharmacokinetic Interaction between the CCR5 Antagonist 873140 and Lopinavir/Ritonavir in Healthy Subjects
K Adkison, A Shachoy-Clark, L Fang, Y Lou, V Otto, M Berrey, and Stephen Piscitelli*
GlaxoSmithKline, Research Triangle Park, NC, USA
      665 Correlation between P-glycorotein and CXCR4 on PBMC and CD4+ Cells Isolated from HIV+ Individuals
Becky Chandler*, S Khoo, M Detsikas, T Walsh, J Williams, D Back, and A Owen
Univ of Liverpool, UK
      666

P-glycoprotein and MRP1 Interactions with Rifampicin
Ruben Hartkoorn*1, C Waitt2, M Chaponda2, G Davies1, B Chandler1, A Owen1, S Ward3, D Back1, and S Khoo1
1Univ of Liverpool, UK; 2Royal Liverpool Univ Hosp, UK; and 3Liverpool Sch of Tropical Med, UK
      667

Racial Differences in Naive CD4+ Lymphocyte P-glycoprotein Activity
Todd Hulgan*, J Donahue, R Kim, C Sutcliffe, B Lishawa, F Nicotera, R D'Aquila, S Raffanti, D Unutmaz, P Rebeiro, H Erdem, C Ingram, C Hawkins, and D Haas
Vanderbilt Univ, Nashville, TN, USA