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Session 20  Oral Abstracts
Neuropathogenesis: Viral Dynamics and Host Responses
Tuesday, 10 am - 12:30 pm
Room: Ballroom 1-2

Moderators:

  Gabriele Arendt
  Univ Hosp of Duesseldorf, Germany

  Francisco González-Scarano
  Univ of Pennsylvania, Philadelphia, US
10:00 am         72 High Cerebrospinal Fluid Neurofilament Protein Levels in AIDS Dementia Complex
Magnus Gisslén*1, P Cinque2, L Hagberg1, R Price3, L Rosengren1, and B Brew4
1Sahlgrenska Akademy, Göteborg Univ, Sweden; 2Hosp San Raffaele, San Raffaele Sci Inst, Milan, Italy; 3Univ of California, San Francisco, US; and 4St Vincent's Hosp, Sydney, Australia
10:15 am         73 Leptin and Neuropsychological Performance: A New Biomarker for Cognitive Function?
Jeannie Huang*, S Letendre, J Beck, M Cherner, S Kolakowski, R Ellis, and HIV Neurobehavioral Res Group
Univ of California, San Diego, US
10:30 am         74 Better Antiretroviral Penetration into the Central Nervous System Is Associated with Lower CSF Viral Load
Scott Letendre*1, E Capparelli1, B Best1, D Clifford2, A Collier3, B Gelman4, J McArthur5, J McCutchan1, D Simpson6, R Ellis1, and the CHARTER Group
1Univ of California, San Diego, US; 2Washington Univ, St Louis, MO, US; 3Univ of Washington, Seattle, US; 4Univ of Texas Med Branch, Galveston, US; 5Johns Hopkins Univ, Baltimore, MD, US; and 6Mt Sinai Sch of Med, New York, NY, US
10:45 am         75 Discordance of Genotypic Resistance between CSF and Plasma Virus in a Multicenter Observational Cohort
Joseph Wong*1,2, S Pillai1,2, R Ellis3, D Clifford4, A Collier5, B Gelman6, J McArthur7, J McCutchan3, S Morgello8, I Grant3, and the CHARTER Group
1VAMC, San Francisco, CA, US; 2Univ of California, San Francisco, US; 3Univ of California, San Diego, US; 4Washington Univ, St Louis, MO, US; 5Univ of Washington, Seattle, US; 6Univ of Texas Med Branch, Galveston, US; 7Johns Hopkins Univ, Baltimore, MD, US; and 8Mt Sinai Sch of Med, New York, NY, US
11:00 am         76 The HIV Env N283 Genetic Variant Is Associated with Brain Infection and Dementia
Rebecca Dunfee*1,2, E Thomas1,2, P Gorry1,2, J Taylor3, K Kunstman3, J Bell4, S Wolinsky3, and D Gabuzda1,2
1Dana-Farber Cancer Inst, Boston, MA, US; 2Harvard Med Sch, Boston, MA, US; 3Northwestern Univ Med Sch, Chicago, IL, US; and 4Univ of Edinburgh, Scotland
11:15 am         77 Longitudinal Analysis of env Population Dynamics in Blood and Cerebrospinal Fluid of SIVsm-infected Macaques
Patrick Harrington*1, M Connell2, P Johnson2, R Meeker1, and R Swanstrom1
1Univ of North Carolina at Chapel Hill, US and 2Children's Hosp of Philadelphia, PA, US
11:30 am         78 Hemochromatosis Gene Polymorphisms and Peripheral Neuropathy during ART: Analysis NWCS 238 of ACTG Study 384
Asha R. Kallianpur*1, T Hulgan1, J Canter2, M Ritchie2, J Haines2, G Robbins3, R Shafer4, D Clifford5, D Haas1, and the AIDS Clin Trials Group
1Vanderbilt Univ Sch of Med, Nashville, TN, US; 2Ctr for Human Genetics Res, Vanderbilt Univ Sch of Med, Nashville, TN, US; 3Harvard Med Sch, Massachusetts Gen Hosp, Boston, US; 4Stanford Univ Sch of Med, Palo Alto, CA, US; and 5Washington Univ Sch of Med, St Louis, MO, US
11:45 am         79 Controlled Study of High-concentration Capsaicin Patch for Painful HIV-associated Distal Sensory Polyneuropathy
David Simpson*1, S Brown2, S Chang3, J Jermano3, and C107 Study Group
1Mt Sinai Sch of Med, New York, NY, US; 2AIDS Res Alliance, West Hollywood, CA, US; and 3NeurogesX, San Carlos, CA, US
12:00 pm         80 Update on Sensory Neuropathies
Justin McArthur
Johns Hopkins Univ Sch of Med, Baltimore, MD, US