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Session 76  Poster Abstracts
HIV-1 Specific Humoral Immune Responses
Monday, 1:30 - 3:30 pm
Poster Hall
      410 Patterns of Cross-clade Neutralizing Antibody Responses in HIV-1-infected Cameroonians
Y Blount1, P Foujungo1, M Kalou1, P Raghunathan1, G Alemnji1, D Montefiori2, M Callahan1, S Butera1, J Nkengasong1, and Chunfu Yang*1
1CDC, Atlanta, GA, US and 2Duke Univ Med Ctr, Durham, NC, US
      411 What Determines the Strain Specificity of the Neutralizing Antibody Response?
Melissa Laird*1, T Igarashi2, M Martin2, and R Desrosiers1
1New England Primate Res Ctr, Harvard Med Sch, Southborough, MA, US and 2NIAID, NIH, DHHS, Bethesda, MD, US
      412 Structural Features of the V3 Region of HIV-1 Env: 3 Classes of Anti-V3 Antibody
Milloni Patel*, N Hoffman, and R Swanstrom
Univ of North Carolina at Chapel Hill, US
      413 Novel HIV-1 Neutralizing Human Antibodies Recognizing Conserved Conformational Epitopes on gp41
Mei-Yun Zhang*1, V Choudhry1, I Sidorov1, B Vu1, H Lu2, D Montefiori3, G Quinnan4, S Jiang2, C Broder4, and D Dimitrov1
1NCI, Frederick, MD, US; 2Lindsley F Kimball Res Inst, New York Blood Ctr, NY, US; 3Duke Univ Med Ctr, Durham, NC, US; and 4Uniformed Svcs Univ of the Hlth Sci, Bethesda, MD, US
      414

V4 Mutations and Neutralization Escape in SIV
Casmiar Nwaigwe*, H Grieser, and K Cole
Univ of Pittsburgh, PA, US
      415 A Role of Mutations in Non-V3 Envelope Regions for Escape from a Broad Neutralizing Anti-V3 Monoclonal Antibody, KD-247, during in vitro Selection
Junji Shibata*1, K Yosihmura1, A Honda1, T Murakami2, A Koito1, and S Matsushita1
1Ctr for AIDS Res, Kumamoto Univ, Japan and 2Chemo-Sero-Therapeutic Res Inst, Kumamoto, Japan
      416

Detection of Antibodies to Major Neutralizing Epitopes of the HIV-1 Envelope in Sera from Long-term Non-progressors: Prevalence and Association with Broadly Neutralizing Activity of these Sera
M Braibant1, S Brunet1, D Costagliola2, C Rouzioux3, H Agut4, B Autran4, and Francis Barin*1
1Univ F Rabelais, Tours, France; 2INSERM U720, Hosp Pitie-Salpetriere, Paris, France; 3Hosp Necker, Paris, France; and 4Hosp Pitié-Salpétrière, Paris, France
      417

Monoclonal Antibodies Directed against the GB Virus C Major Envelope Glycoprotein Neutralize HIV Infectivity Differentially in PBMC than in TZB-bl Cells
Jinhua Xiang*1, J McLinden1, Q Chang1, D Klinzman1, T Kaufman1, D Montefiori2, A Engel3, G Hess4, D Zdunek3, and J Stapleton1
1VAMC and Univ of Iowa, Iowa City, US; 2Duke Univ Sch of Med, Durham, NC, US; 3Roche Diagnostics, Penzburg, Germany; and 4Roche Diagnostics, Mannheim, Germany