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Session 59  Poster Abstracts
Virus-Cell Interactions: Co-Receptor Usage
Monday, 1 - 4 pm
Poster Hall
      250

Extension of gp120 Env Co-receptor Use to CXCR4 Is Associated with Disease Progression in LTNP Infected with nef-Defective HIV-1
A Crotti1, S Ghezzi1, E Santagostino2, and Elisa Vicenzi*1
1San Raffaele Sci Inst, Milan, Italy and 2A Bianchi Bonomi Hemophilia and Thrombosis Ctr, Milan, Italy
      251 Dual-tropic HIV Display a Range of Ability to Use the CXCR4 or CCR5 Co-receptors
Jonathan Toma*, J Whitcomb, S Fransen, N Parkin, C Petropoulos, and W Huang
Monogram Biosci, South San Francisco, CA, US
      252 Sequential Turnover of env Variants and Co-receptor Switching during HIV-1 Chronic Infection
Julie Nelson*1,2, Julie Nelson*1,2, T Riddle2, N Shire2, M Sherman2, K Franco2, and H Sheppard3
1Univ of North Carolina at Chapel Hill, US; 2Univ of Cincinnati, OH, US; and 3California Dept of Hlth Svcs, Richmond, US
      253

HIV Envelope Functional Evolution during Co-receptor Switching
Donald Mosier*1, R Nedellec1, A Ramos1, J Miamidian2, J Reeves3, and C Pastore1
1Scripps Res Inst, La Jolla, CA, US; 2Univ of Pennsylvania, Philadelphia, US; and 3Monogram Biosci, South San Francisco, CA, US
      254 Prevalence of X4 Viruses in Patients Infected with HIV-1 Non-B Subtypes
Carolina Garrido*1, N Chueca2, A Aguilera3, K Skrabal4, E Poveda1, S Carlos2, F García2, J L Faudon4, C de Mendoza1, and V Soriano1
1Hosp Carlos III, Madrid, Spain; 2Hosp Univ San Cecilio, Granada, Spain; 3Hosp Xeral Santiago de Compostela, Spain; and 4Eurofins, Paris, France
      255 HIV-1 Envelopes from the Early and Chronic Phases of Infection Have Different Host Receptor Interactions
A Fellows1, B Kwambana1, J Overbaugh2, and Manish Sagar*1
1Brigham and Women's Hosp, Harvard Med Sch, Boston, MA, US and 2Fred Hutchinson Cancer Res Ctr, Seattle, WA, US
      256 HCV Infection Is Associated with Decreased Co-receptor Switching and Increased Viral Diversity of HIV-1 in Co-infected Subjects
K Franco1, N Shire1, T Riddle1, H Sheppard2, J Goedert3, K Sherman1, Julie Nelson*1,4, and Julie Nelson*1,4
1Univ of Cincinnati, OH, US; 2California Dept of Hlth Svcs, Richmond, US; 3NCI, Rockville, MD, US; and 4Univ of North Carolina at Chapel Hill, US
      257 Evolution of HIV-1 X4 Phenotypein vivo in Tissues and Longitudinal PBMC Samples Is Driven by Episodic Positive Selection
Marco Salemi*1, B Burkhardt1, S Pomeroy1, A Lowe1, G Ghaffari1, J Sleasman2, and M Goodenow1
1Univ of Florida, Gainesville, US and 2Univ of Florida and All Children's Hosp, St Petersburg, US
      258 The CCR7 Ligands CCL19 and CCL21 Increase Permissiveness of Resting CD4+ T Cells to HIV Infection
Suha Saleh*1, A Solomon1, F Wightman1, M Xhilaga1, P Cameron1,2, P Cameron1,2, S Lewin1,2, and S Lewin1,2
1Monash Univ, Melbourne, Australia and 2Alfred Hosp, Melbourne, Australia
      259 HIV-1 Infection of Human Lymphoid Tissue and Rectal Mucosa ex vivo
J C Grivel1, J Elliott2, A Biancotto1, A Adler2, I McGowan2, Peter Anton*2, and L Margolis1
1Natl Inst of Child Hlth and Human Devt, NIH, Bethesda, MD, US and 2Univ of California, Los Angeles Ctr for HIV Prevention Res, US
      260

Distinct DC-SIGN and DC-SIGNR Genetic Polymorphism among Han Chinese
Hui Wang*1, Y Xu2, Y Hu3, C Wang2, F Liu4, L Li1, X Tong1, X Xiao3, B Zhou1, and T Zhu2
1Shenzhen Municipal Hosp of Infectious Diseases, PR China; 2Univ of Washington Sch of Med, Seattle, US; 3Jinan Univ, Guangzhou, PR China; and 4Dongguan Blood Ctr, Dongguan, PR China