Session 83 - CROI 2007

Session 83 Poster Abstracts
Special Issues in Immunopathogenesis
Wednesday, 1 - 4 pm
Poster Hall

438	Toll-like Receptor 2 May Be Involved in the Immunopathogenesis of Human T-cell Lymphotropic Virus-associated Myelopathy/Tropical Spastic Paraparesis Hugo Marcelo Barbosa*¹, K Carvalho¹, H Tomiyama¹, W Neto², I Nukui², E Sabino², M Chieia¹, and E Kallas¹ ¹Federal Univ of Sao Paulo, Brazil and ²Sao Paulo Blood Bank, Brazil
439	Gender-related Immune Dysfunction on HTLV-I-infected Asymptomatic Patients: Implication on Immunopathogenesis of Adult T-cell Leukemia and Tropical Spastic Paraparesis/HTLV-I-associated Myelopathy Fernanda Bruno*¹, H Barbosa¹, K Carvalho¹, H Tomiyama¹, W Neto², I Nukui², E Sabino², M Chieia², and E Kallas¹ ¹Federal Univ of Sao Paulo, Brazil and ²Blood Bank of Sao Paulo, Brazil
440	Functional Profile of HIV-specific T Cells in Rectal Mucosa J Critchfield¹, D Lemongello¹, D Young¹, M Morris¹, M Schreiber¹, B Autret¹, J Garcia¹, D Asmuth¹, R Pollard^1,1, R Pollard^1,1, Barbara Shacklett^1,1, and Barbara Shacklett^1,1 ¹Univ of California, Davis, US
441	Induction of Potent Local Cellular Immunity in X4 SHIV_SF33A Vaginally Exposed Seronegative Macaques Silvana Tasca*¹, L Tsai¹, N Trunova¹, A Gettie¹, M Saifuddin², R Bohm³, L Chakrabarti⁴, and C Cheng Mayer¹ ¹Aaron Diamond AIDS Res Ctr, The Rockefeller Univ, New York, NY, US; ²Conrad Eastern Virginia Med Sch, Arlington, US; ³Tulane Natl Primate Res Ctr, Covington, LA, US; and ⁴Pasteur Inst, Paris, France
442	Breast Milk CD4⁺ T Cells Express High Levels of CCR5 and CXCR4 and Are Preserved in HIV Infection Athena Kourtis*¹, C Ibegbu², R Theiler³, Y X Wu², D Jamieson¹, M Lindsay³, S Butera⁴, and A Duerr¹ ¹Natl Ctr for Chronic Disease Prevention and Hlth Promotion, CDC, Atlanta, GA, US; ²Emory Vaccine Ctr, Emory Univ, Atlanta, GA, US; ³Emory Univ Sch of Med, Atlanta, GA, US; and ⁴Natl Ctr for HIV, Viral Hepatitis, STD, and TB Prevention, CDC, Atlanta, GA, US
443	Variable Copy Numbers of Several Chemokine Genes in Adolescents with and without HIV-1 Infection W Shao, Jianming Tang*, W Song, C Wang, Y Li, C Wilson, and R Kaslow Univ of Alabama at Birmingham, US
444	Antibody Protein Arrays of CD4⁺ and CD8⁺ T Cells from HIV⁺ Individuals Show Novel Cluster of Differentiation Antigens Markers for HIV Disease Jingqin Wu*¹, B Wang¹, D Dwyer¹, K Evans², L Belov², J Crisp², and N Saksena¹ ¹Westmead Millennium Inst, Sydney, Australia and ²Medsaic Pty Ltd, Natl Innovation Ctr, Australian Technology Park, Sydney
445	A Novel Mechanism of Immunological Synapse Dysfunction Mediated by an Impairment of Adenosine Deaminase-induced Co-stimulation of T-cell Activation in HIV-1-infected Patients José M Martínez-Navío*¹, R Pacheco¹, N Climent², F García², M Nomdedeu², M Plana², J Gatell², T Gallart², C Lluis¹, and R Franco¹ ¹Univ of Barcelona, Spain and ²Hosp Clin-IDIBAPS, Univ of Barcelona, Spain
446	Genetics, Epigenetics, and Expression of CCL5 Gene that Encodes RANTES, a Chemokine with Potent Anti-HIV-1 Properties Wei Song*, L Zhou, C Wang, Y Li, C Wilson, R Kalsow, and J Tang Univ of Alabama at Birmingham, US
447	Comparative Analysis of HIV-related and Post-Autologous Hematopoietic Stem Cell Transplantation T-cell Deficiency Alessandra Bandera*¹, M Schenal², L Gazzola³, D Trabattoni², F Franzetti⁴, M Clerici², and A Gori³ ¹Busto Arsizio Hosp, Italy; ²Univ of Milan, Italy; ³San Paolo Hosp, Univ of Milan, Italy; and ⁴Inst of Infectious Disease and Tropical Med, Univ of Milan, Italy
448	Profile of CD127 Expression in Different CD4 and CD8 T-cell Subsets in Patients with Chronic HIV Infection, and Changes during ART Jose Benito*, M Lopez, S Lozano, A Cascajero, J Gonzalez-Lahoz, and V Soriano Hosp Carlos III, Madrid, Spain
449	18F-FDG PET in HIV Infection: Correlation with Virological and Immunological Parameters in Different Clinical Stages of Disease miriam cesari*¹, K marzo², E orunesu³, M pacei⁴, G bechi⁴, F franzetti¹, G lucignani³, M clerici⁴, A gori⁵, and A chiti² ¹Luigi Sacco Hosp, Univ of Milan, Italy; ²Inst Clin Humanitas, IRCCS, Milan, Italy; ³Inst of Radiological Sci, Univ of Milan, Italy; ⁴LITA VIALBA, Univ of Milan, Italy; and ⁵San Paolo Hosp Univ Med Sch, Milan, Italy
450	Early Changes in Activation Predict Antiretroviral Success in Salvage Therapy of HIV Infection Brett Shepard*¹, M Loutfy², J Raboud², C Diong², F Mandy³, M Bergeron³, C Kovacs², and A Badley¹ ¹Mayo Clin Coll of Med, Rochester, MN, US; ²Univ of Toronto, Canada; and ³Natl HIV Immunology Lab, Ottawa, Canada
451	Percentage and Relative Levels of Expression of PD-1 and PD-L1 in Treated HIV-1⁺ Individuals as Markers of Disease Status and Therapy Efficacy Guglielmo Rosignoli*¹, A Cranage¹, C Burton¹, A Steel², B Gazzard², F Gotch¹, and N Imami¹ ¹Imperial Coll, London, UK and ²Chelsea and Westminster Hosp, London, UK
452	Influence of PD1 Genotype on Virological and Immunological Response in Patients Initiating ART Neill Liptrott*¹, T Mahungu², M Youle², M Johnson², C Smith², D Back¹, S Khoo¹, and A Owen¹ ¹Univ of Liverpool, UK and ²Royal Free Ctr for HIV Med, London, UK
453	Direct Relation between Monocyte Gene Expression, Circulating Count, and Apoptosis Resistance following Therapy Interruption: Increased Metallothionein Gene Expression Associated with Functional Resistance against Apoptotsis Induction Andrea Raymond*¹, M Giri¹, E Papasavvas¹, A Hancock¹, A Mackiewicz¹, B Thiel¹, K Mounzer², and L Montaner¹ ¹Wistar Inst, Philadelphia, PA, US and ²Philadelphia Field Initiating Group for HIV Trials, PA, US
454	Effects of HAART Interruption in Acquired Humoral and Cellular Responses to Recommended Vaccines Pedro Castro*, R González, A Lopez, M Plana, A Vilella, M Nomdedeu, T Pumarola, J Bayas, J Gatell, and F García Hosp Clin, Barcelona, Spain
455	HAART Therapy in HIV^{+^{Patients Increases IL-7 Responsiveness of Peripheral T Cells ex vivo}} Amanda Leone*¹, G Lehrman¹, M Jain¹, P Keiser¹, L Picker², F Villinger³, and D Sodora¹ ¹Univ of Texas Southwestern Med Ctr, Dallas, US; ²Oregon Natl Primate Ctr, Beaverton, US; and ³Emory Univ, Atlanta, GA, US
456	Effect of Drug Resistance on the Expression of Interleukin-7 Receptor and Activation Markers on CD4 and CD8 T-cell Subsets in HIV-1-infected Patients Jean-Pierre Routy*¹, F Mercier¹, V Calvez², T Klimkait³, F Hamy³, and M R Boulassel¹ ¹McGill Univ Hlth Ctr, Montreal, Canada; ²Pitie-Salpetriere Hosp, Paris, France; and ³InPheno AG, Basel, Switzerland