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Session 87
Poster Abstracts
New RTIs and Pis
Monday, 1 - 4 pm
Poster Hall |
487
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Antiviral Activity of Novel NRTI
Edward Karamov*1, M Kukhanova2, G Kornilaeva1, T Pavlova1, and M Jasko2
1Ivanovsky Inst of Virology, Moscow, Russia and 2Engelhardt Inst of Molecular Bio, Moscow, Russia |
| 488 |
Racivir Demonstrates Safety and Efficacy in Patients Harboring HIV with the M184V Mutation and <3 TAM
Pedro Cahn*1, N Sosa2, A Wiznia3, M Patel3, D Ward4, F Palella5, J Sierra-Madero6, D Wheeler7, E DeJesus8, M Otto9, and Racivir 201 Study Team
1Fndn Huesped, Buenos Aires, Argentina; 2Med Res Ctr, Panama City, Panama; 3Jacobi Med Ctr, Bronx, NY, US; 4Washington, DC, US; 5Northwestern University, Chicago, IL, USA; 6Inst Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico; 7CARE-ID, Annandale, MD, US; 8Orlando Immunology Ctr, FL, US; and 9Pharmasset, Inc, Princeton, NJ, US |
| 489 |
IDX12899 and IDX12989, Novel NNRTI with Potent Anti-HIV Activity, Enhanced Barrier to Resistance and Favorable Pharmacokinetic Profile
Douglas Richman*1, C Dousson2, R Storer3, A Moussa3, J Randall3, E Bridges3, M Liuzzi4, J Jakubik3, M Seifer3, and D Standring3
1Univ of California, San Diego, US; 2Idenix Pharma, Montpellier, France; 3Idenix Pharma, Cambridge, MA, US; and 4Idenix Pharma, Cagliari, Italy |
| 490 |
Mechanism of Synergy between Efavirenz and Zidovudine: Role of HIV-1 Reverse Transcriptase RNase H Activity
Jessica Radzio*1,2, Jessica Radzio*1,2, and N Sluis-Cremer2
1Univ of Pittsburgh Grad Sch of Publ Hlth, PA, US and 2Univ of Pittsburgh Sch of Med, PA, US |
| 491 |
Profile of GS-8374, a Novel Phosphonate-containing HIV PI: in vitro Antiretroviral Activity, Toxicity, and Resistance
Christian Callebaut*1, K Stray1, L Tsai1, L Xu1, G X He1, A Mulato1, T Priskich2, N Parkin2, W Lee1, and T Cihlar1
1Gilead Sci, Foster City, CA, US and 2Monogram Biosci, South San Francisco, CA, US |
492
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A Novel bis-Tetrahydrofranylurethane-containing Nonpeptidic PI GRL-98065 Potent against Multi-PI-Resistant HIV in vitro
Masayuki Amano*1, Y koh1, A Ghosh2, H Mitsuya1,3, and H Mitsuya1,3
1Kumamoto Univ Sch of Med, Japan; 2Purdue Univ, West Lafayette, IN, US; and 3NCI, NIH, Bethesda, MD, US |
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