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Session 88
Poster Abstracts
Targeting CCR5 and CXCR4
Monday, 1 - 4 pm
Poster Hall |
| 493 |
Structural/Molecular Analysis of HIV Inhibition by Small Molecule CCR5 Inhibitors
Kenji Maeda*1,2, Kenji Maeda*1,2, D Das1, K Tsuchiya1, P Yin1, H Ogata-Aoki2, H Nakata1,2, H Nakata1,2, R Norman1, Y Takaoka3, H Mitsuya1,2, and H Mitsuya1,2
1NCI, NIH, Bethesda, MD, US; 2Kumamoto Univ Grad Sch of Med and Pharma Sci, Japan; and 3Minase Res Inst, Ono Pharma Co Ltd, Osaka, Japan |
| 494 |
Study of Dynamics of Cellular CCR5 and Its Alterations by CCR5 Inhibitors Using YFP-tagged CCR5-expressing Cells
Hirotomo Nakata*1,2, Hirotomo Nakata*1,2, W Kamata1, H Ogata-Aoki1, K Maeda2, H Mitsuya1,2, and H Mitsuya1,2
1Kumamoto Univ Sch of Med, Japan and 2NCI, NIH, Bethesda, MD, US |
495
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Understanding the Interactions between CXCR4 and AMD11070, a First-in-class Small-molecule Antagonist of the HIV Coreceptor
Rebecca Wong*, V Bodart, M Metz, J Labrecque, G Bridger, and S Fricker
AnorMED Inc, Langley, Canada |
496
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An Improved Animal Model for X4 HIV-1 Infection: Human IL-4-Transgenic hu-PBL-SCID Mice
Kazu Okuma*1, R Tanaka1, M Ito2, S Kumakura3, M Yanaka3, W Sugiura4, M Nishizawa4, N Yamamoto4, and Y Tanaka1
1Univ of the Ryukyus, Okinawa, Japan; 2Central Inst for Experimental Animals, Kanagawa, Japan; 3Kureha Corp, Tokyo, Japan; and 4Natl Inst of Infectious Diseases, Tokyo, Japan |
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